| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3838 |
Name | KPNA2 |
Synonymous | karyopherin alpha 2 (RAG cohort 1, importin alpha 1);KPNA2;karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
Definition | RAG cohort 1|RAG cohort protein 1|SRP1-alpha|importin alpha 1|importin alpha 2|importin subunit alpha-1|importin subunit alpha-2|importin-alpha-P1|karyopherin subunit alpha-2|pendulin |
Position | 17q24.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | p53(h) + SRP1alpha(h) <==> p53(h):SRP1alpha(h) (binding) | MAGEH1(h) + SRP1alpha(h) <==> MAGEH1(h):SRP1alpha(h) (binding) | KPNA2(h) --> SRP1alpha(h) (expression). | NF-kappaB1-p50(h) + SRP1alpha(h) <==> NF-kappaB1-p50(h):SRP1alpha(h) (binding) | SRP1alpha(h) + RelA-p65(h) <==> SRP1alpha(h):RelA-p65(h) (binding) | SRP1alpha(h) + (NF-kappaB1-p50(m.s.))2 <==> SRP1alpha(h):(NF-kappaB1-p50(m.s.))2 (binding) | RelA-p65(h) + NF-kappaB1-p50(h) + SRP1alpha(h) <==> RelA-p65(h):NF-kappaB1-p50(h):SRP1alpha(h) (binding) | SRP1alpha(h) + Pax-5(m) <==> SRP1alpha(h):Pax-5(m) (binding) | SRP1alpha(h) + p53-isoform1(h) <==> SRP1alpha(h):p53-isoform1(h) (binding) | SRP1alpha(h) --> CDKN1A(h) (transactivation) | nupl1-p58(r) + SRP1alpha(h) <==> nupl1-p58(r):SRP1alpha(h) (binding) | vcp(h) + SRP1alpha(h) <==> vcp(h):SRP1alpha(h) (binding) | KPNA2(h) --> SRP1alpha(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 24 | Phosphoserine. | Swiss-Prot 53.0 | 62 | Phosphoserine. | Swiss-Prot 53.0 | 490 | Phosphoserine. | Swiss-Prot 53.0 | 62 | Phosphoserine | 16565220;17081983 | Phospho.ELM 6.0 | 24 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for KPNA2 | ||