Entrez Gene

Basic Information
Gene ID	3566
Name	IL4R
Synonymous	interleukin 4 receptor;IL4R;interleukin 4 receptor
Definition	IL-4 receptor subunit alpha\|IL4R nirs variant 1\|interleukin-4 receptor alpha chain\|interleukin-4 receptor subunit alpha
Position	16p12.1-p11.2
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
IL-4(h) + IL-4Ralpha(h) <==> IL-4(h):IL-4Ralpha(h) (binding)
IL-4Ralpha(h) + Jak1(h) <==> IL-4Ralpha(h):Jak1(h) (binding)
IL-4Ralpha(h) + Jak1(m) <==> IL-4Ralpha(h):Jak1(m) (binding)
IL-4Ralpha(h) + Jak2(h) <==> IL-4Ralpha(h):Jak2(h) (binding)
IL-4Ralpha(h) + ATP --JakA(v.s.)--> IL-4Ralpha(h){pY} + ADP (phosphorylation)
IL-13(h) + IL-13Ralpha1(h) + IL-4Ralpha(h) <==> IL-4Ralpha(h):IL-13Ralpha1(h):IL-13(h) (binding)
IL-4Ralpha(h) + gamma-c(h) <==> IL-4Ralpha(h):gamma-c(h) (binding)
IL-4(h) + IL-4Ralpha(h) + IL-13Ralpha1(h) <==> IL-4(h):IL-4Ralpha(h):IL-13Ralpha1(h) (binding)
IL-4Ralpha(h) + SHP-1(h) <==> IL-4Ralpha(h):SHP-1(h) (binding)
IL-4Ralpha(h) + ATP --> IL-4Ralpha(h){pY} + ADP (phosphorylation)
IL4R(h) --> IL-4Ralpha(h) (expression).
IL4R(h) --> IL-4Ralpha(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
53	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
98	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
128	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
134	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
176	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
209	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
497	Phosphotyrosine.		Swiss-Prot 53.0
575	Phosphotyrosine (Probable).		Swiss-Prot 53.0
603	Phosphotyrosine (Probable).		Swiss-Prot 53.0
631	Phosphotyrosine (Probable).		Swiss-Prot 53.0
713	Phosphotyrosine	9670964	Phospho.ELM 6.0
497	Phosphotyrosine	9545332;9697832	Phospho.ELM 6.0
575	Phosphotyrosine	10358772	Phospho.ELM 6.0
631	Phosphotyrosine	10358772	Phospho.ELM 6.0
603	Phosphotyrosine	10358772;9712048	Phospho.ELM 6.0

Transcription Factors [Top]