Entrez Gene

Basic Information
Gene ID	28964
Name	GIT1
Synonymous	G protein-coupled receptor kinase interacting ArfGAP 1;GIT1;G protein-coupled receptor kinase interacting ArfGAP 1
Definition	ARF GAP GIT1\|ARF GTPase-activating protein GIT1\|CAT-1\|CAT1\|G protein-coupled receptor kinase interactor 1\|G protein-coupled receptor kinase-interactor 1\|GRK-interacting protein 1\|cool-associated and tyrosine-phosphorylated protein 1
Position	17p11.2
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
BARD1(h) + Cat-1(h) <==> BARD1(h):Cat-1(h) (binding)
Mi2-alpha(h) + Cat-1(h) <==> Mi2-alpha(h):Cat-1(h) (binding)
huntingtin(h) + Cat-1(h) <==> huntingtin(h):Cat-1(h) (binding)
Cat-1(h) + ATP --p65PAK(h)--> Cat-1(h){pS} + ADP (phosphorylation)
PAK2(h) + Cat-1(h) <==> PAK2(h):Cat-1(h) (binding)
rgs2(h) + Cat-1(h) <==> rgs2(h):Cat-1(h) (binding)
heme oxygenase 2(h) + Cat-1(h) <==> heme oxygenase 2(h):Cat-1(h) (binding)
CAB(h) + Cat-1(h) <==> CAB(h):Cat-1(h) (binding)
PFDN1(h) + Cat-1(h) <==> PFDN1(h):Cat-1(h) (binding)
TRF1(h) + Cat-1(h) <==> TRF1(h):Cat-1(h) (binding)
hbxip(h) + Cat-1(h) <==> hbxip(h):Cat-1(h) (binding)
PMF1(h) + Cat-1(h) <==> PMF1(h):Cat-1(h) (binding)
ARS2(h) + Cat-1(h) <==> ARS2(h):Cat-1(h) (binding)
WDR33(h) + Cat-1(h) <==> WDR33(h):Cat-1(h) (binding)
DDX24(h) + Cat-1(h) <==> DDX24(h):Cat-1(h) (binding)
TRB3(h) + Cat-1(h) <==> TRB3(h):Cat-1(h) (binding)
GIT1(h) --> Cat-1(h) (expression).
Cat-1-isoform1(h) + BARD1(h) <==> Cat-1-isoform1(h):BARD1(h) (binding)
Cat-1-isoform1(h) + Mi2alpha-isoform1(h) <==> Cat-1-isoform1(h):Mi2alpha-isoform1(h) (binding)
GIT1(h) --> Cat-1-isoform1(h) (expression).
GIT1(h) --> Cat-1-isoform2(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
361	Phosphoserine (By similarity).		Swiss-Prot 53.0
362	Phosphoserine (By similarity).		Swiss-Prot 53.0
385	Phosphoserine.		Swiss-Prot 53.0
388	Phosphoserine.		Swiss-Prot 53.0
545	Phosphotyrosine.		Swiss-Prot 53.0
554	Phosphotyrosine.		Swiss-Prot 53.0
592	Phosphoserine.		Swiss-Prot 53.0
598	Phosphotyrosine.		Swiss-Prot 53.0
388	Phosphoserine	15302935	Phospho.ELM 6.0
545	Phosphotyrosine	15592455	Phospho.ELM 6.0
554	Phosphotyrosine	15592455	Phospho.ELM 6.0
508	Phosphoserine	16246726	Phospho.ELM 6.0

Transcription Factors [Top]