| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 28964 |
Name | GIT1 |
Synonym | G protein-coupled receptor kinase interacting ArfGAP 1;GIT1;G protein-coupled receptor kinase interacting ArfGAP 1 |
Definition | ARF GAP GIT1|ARF GTPase-activating protein GIT1|CAT-1|CAT1|G protein-coupled receptor kinase interactor 1|G protein-coupled receptor kinase-interactor 1|GRK-interacting protein 1|cool-associated and tyrosine-phosphorylated protein 1 |
Position | 17p11.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Arf6 signaling events;PID Curated;200060 |
Pathway | Regulation of CDC42 activity;PID Curated;200059 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | Epithelial cell signaling in Helicobacter pylori infection;KEGG PATHWAY;hsa05120 |
Pathway | Aurora A signaling;PID Curated;200166 |
Pathway | Paxillin-dependent events mediated by a4b1;PID Curated;200117 |
Pathway | Stabilization and expansion of the E-cadherin adherens junction;PID Curated;200155 |
Pathway | Paxillin-independent events mediated by a4b1 and a4b7;PID Curated;200178 |
Disease | Huntington disease;FunDO |
External Links | |
Links to Entrez Gene | 28964 |
Links to all GeneRIF Items | 28964 |
Links to iHOP | 28964 |
Sequence Information | |
Nucleotide Sequence | >28964 : length: 3778 GCGGCGCGGGGCGGAGGGCGCCCGAGGGCGAGCGGGCAGGCGGGCACGGCGGGTTCCGGG CCAGCCCCGGGGCGGACGGTTGGCCGGGCGCGCGGAGCCTCGCCGGGGCCTCGCCGGAGC CGGGCCGGGCAGCAGGGGCCGCCGCCGCCGCCCGGGCCCGCCGCCCGCGCCCCCCACGCT GGCCCAGAGGGCTGCGGCCGCGTCGCCGCTGAGGATGTCCCGAAAGGGGCCGCGAGCGGA GGTGTGTGCGGACTGCAGCGCCCCGGACCCTGGCTGGGCATCCATCAGCAGGGGTGTGCT GGTGTGTGACGAGTGCTGCAGCGTGCACCGGAGCCTGGGACGCCACATCTCCATTGTCAA GCACCTTCGCCACAGCGCCTGGCCTCCCACGCTGCTGCAGATGGTGCACACGCTTGCCAG CAACGGGGCCAACTCCATCTGGGAGCACTCCCTGCTGGACCCCGCACAAGTGCAGAGCGG CCGGCGTAAAGCCAACCCCCAAGACAAAGTCCACCCCATCAAGTCAGAGTTCATCAGGGC CAAGTACCAGATGCTGGCATTTGTGCACAAGCTTCCCTGCCGGGACGATGATGGAGTCAC CGCCAAAGACCTCAGCAAGCAACTACACTCGAGCGTGCGGACAGGCAACCTGGAGACATG TCTGCGCCTGCTCTCCCTGGGTGCCCAGGCCAACTTCTTCCACCCAGAGAAGGGCACCAC ACCTCTGCACGTGGCTGCCAAGGCAGGACAGACACTGCAGGCCGAGCTGCTTGTAGTGTA TGGGGCTGACCCTGGCTCCCCTGATGTTAATGGCCGCACACCCATTGACTATGCCAGGCA GGCGGGGCACCATGAGCTGGCGGAAAGGCTGGTTGAGTGCCAATATGAGCTCACTGACCG GCTGGCCTTCTACCTCTGTGGACGCAAGCCGGATCACAAGAATGGGCATTACATCATCCC ACAGATGGCTGACAGATCTCGGCAAAAGTGCATGTCTCAGAGCCTTGACTTATCCGAATT GGCCAAAGCTGCTAAGAAGAAGCTGCAGGCGCTCAGCAACCGGCTTTTTGAGGAACTCGC CATGGACGTGTATGACGAGGTGGATCGAAGAGAAAATGATGCAGTGTGGCTGGCTACCCA AAACCACAGCACTCTGGTGACAGAGCGCAGTGCCGTGCCCTTCCTGCCTGTTAACCCGGA ATACTCAGCCACGCGGAATCAGGGGCGACAAAAGCTGGCCCGCTTTAATGCCCGAGAGTT TGCCACCTTGATCATCGACATTCTCAGTGAGGCCAAGCGGAGACAGCAGGGCAAGAGCCT GAGCAGCCCCACAGACAACCTCGAGCTGTCTCTGCGGAGCCAGAGTGACCTCGACGACCA ACACGACTACGACAGCGTGGCCTCTGACGAGGACACAGACCAGGAGCCCCTGCGCAGCAC CGGCGCCACTCGGAGCAACCGGGCCCGGAGCATGGACTCCTCGGACTTGTCTGACGGGGC TGTGACGCTGCAGGAGTACCTGGAGCTGAAGAAGGCCCTGGCTACATCGGAGGCAAAGGT GCAGCAGCTCATGAAGGTCAACAGTAGCCTGAGCGACGAGCTCCGGAGGCTGCAGCGAGA GATCCACAAGCTGCAGGCGGAGAACCTGCAGCTCCGGCAGCCTCCAGGGCCGGTGCCCAC ACCTCCACTCCCCAGTGAACGGGCGGAACACACACCCATGGCGCCAGGCGGGAGCACACA CCGCAGGGATCGCCAGGCCTTTTCCATGTATGAACCTGGCTCTGCCCTGAAGCCCTTTGG GGGCCCCCCTGGGGACGAGCTCACTACGCGGCTGCAGCCTTTCCACAGCACTGAGCTAGA GGACGACGCCATCTATTCAGTGCACGTCCCTGCTGGCCTTTACCGGATCCGGAAAGGGGT GTCTGCCTCAGCTGTGCCCTTCACTCCCTCCTCCCCGCTGCTGTCCTGCTCCCAGGAGGG AAGCCGCCACACGAGCAAGCTTTCCCGCCACGGCAGTGGAGCCGACAGTGACTATGAGAA CACGCAAAGTGGGGACCCACTGCTGGGGCTGGAAGGGAAGAGGTTTCTAGAGCTGGGCAA AGAGGAAGACTTCCACCCAGAGCTGGAAAGCCTGGATGGAGACCTAGATCCTGGGCTTCC CAGCACAGAGGATGTCATCTTGAAGACAGAGCAGGTCACCAAGAACATTCAGGAACTGTT GCGGGCAGCCCAGGAGTTCAAGCATGACAGCTTCGTGCCCTGCTCAGAGAAGATCCATTT GGCTGTGACCGAGATGGCCTCCCTCTTCCCAAAGAGGCCAGCCCTGGAGCCAGTGCGGAG CTCACTGCGGCTGCTCAACGCCAGCGCCTACCGGCTGCAGAGTGAGTGCCGGAAGACAGT GCCCCCAGAGCCCGGCGCCCCAGTGGACTTCCAGCTGCTGACTCAGCAGGTGATCCAGTG CGCCTATGACATCGCCAAGGCTGCCAAGCAGCTGGTCACCATCACCACCCGAGAGAAGAA GCAGTGACCTCTCTCCCCACACCCTCACCTGCACCCTAGGACCTCACTGGCCATAGGAGC TGGGCCACTCCAGACATTAATCCCCACCCCAACAGAGCCACTGGCACAAGTGCCCTTAGT GCTGCCACACTCCCTGGCAGCCAGGTGCCCTGGTGCCCACCCCTGTCGAGCCCCTAAGGA TGGGGAGGTGGGGGGGCAGGAGCTTCTGTCCCCCACATTCCATGCACCTCCCCTCTGTAT ATAGCATCTCCCCCCTCCTAGTGAGCAGGGGCCTGCAAGGCATCACTCCCAGCCCCTCGC CTTCTAGGGCACCCTCAGCAAAGGGGCAGGTGGGGACACTCCAAGTGGGGCAGCTCTCCG TACATGCGCCCCACCCCCATGAGCCAGTTCAGCCCTACTGGGGGCTGAGCGGGGGCATCC CCTCCTTTGTACATAGTCTCCATGGATGTCCCTGCCCTGTAGCCACCAGCCCCTTGCTGC TCTCCCTTTAATGCCATATGGCCCCTGCCTAGGGCACAGGCCCCAACCTGTGTGCTGGGG TCCCCAGCAGCAAACACTGGAAAGTCTGTTTTTTTTTTTTCTTTCTTCTTCCCCACCCCT TAATTTTAACTTTGTGGTAACTGAGTGCCCCCGCGTGCCTGCGTGTTGAGTGTGTGGGCG GCAGTGCCGTTCCGGAGGCCTGGTCCATCTGGAGTTTTGAGGGGTGAGGGGACCAGAGCA GTGGGACCAGCATGGGGATCAGCTTCCCTTCCCCACCTGGAGCCAGGGACTGTCCGGGTA GCCAGTTTTGGTCCTGCCAGCTGCCTCCCTGATCCCTCCCCACTCTCGCCCCTTCTCTAT GAACTTAAATCAAAAACCACTTCCCTCCATCTCCTCCTGCTCCTGCGTGGAGGGGGAATG TGTGCTGGCTAGGGTGGAGGACTGAGCACCTGAGCCTGGGGCTGGCTCCCCGGGGTCCCC GACTCAGCTGGTGGCTGTGGAGCTGAGTCCCCTCCCCGTAACCTCTGCAAGGCCAGCACC CACCATCACTACCTGCACCTGCTGTGGTCCCACCCTCTGGAGGCCTGGGAACCTGGCTGC AGCCTGGGAAGGCTGGAGAGGCAGACGGTGGGACCCACCAGCTCTCTCCCCATCCCGCTT CTTCCCTGGGGGCCAGGCCCTACCTGTGTGGTGGTGGGTGGGCTGTCAAGACGTGTCATG TACATTTGTATCAAAAATAAAGAAGTGACCATGAGCTGTTAAAAAAAAAAAAAAAAAA |
Protein Sequence | >28964 : length: 777 MSRKGPRAEVCADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTL LQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKL PCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQT LQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPD HKNGHYIIPQMADRSRQKCMSQSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRE NDAVWLATQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSEA KRRQQGKSLSSPTDNLELSLRSQSDLDDQHDYDSVASDEDTDQEPLRSTGATRSNRARSM DSSDLSDGAVTLQEYLELKKALATSEAKVQQLMKVNSSLSDELRRLQREIHKLQAENLQL RQPPGPVPTPPLPSERAEHTPMAPGGSTHRRDRQAFSMYEPGSALKPFGGPPGDELTTRL QPFHSTELEDDAIYSVHVPAGLYRIRKGVSASAVPFTPSSPLLSCSQEGSRHTSKLSRHG SGADSDYENTQSGDPLLGLEGKRFLELGKEEDFHPELESLDGDLDPGLPSTEDVILKTEQ VTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKPHSCPLQRPALEPVRSSLRL LNASAYRLQSECRKTVPPEPGAPVDFQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ |