Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

2690

Name

GHR

Synonymous

growth hormone receptor;GHR;growth hormone receptor

Definition

GH receptor|growth hormone binding protein|serum binding protein|somatotropin receptor

Position

5p13-p12

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

GHR(h) + ATP --> GHR(h){pY} + ADP (phosphorylation)
Jak2(h){pY} + GHR(h) <==> Jak2(h){pY}:GHR(h) (binding)
STAT5(h) + GHR(h) <==> STAT5(h):GHR(h) (binding)
GHR(h) --> GHR(h) (expression).
GHR(h) --> GHR(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

46N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
115N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
156N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
161N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
200N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
332Phosphotyrosine (JAK2)9121492Phospho.ELM 6.0
487Phosphotyrosine (JAK2)9121492Phospho.ELM 6.0
534Phosphotyrosine (JAK2)9121492;8647880Phospho.ELM 6.0
566Phosphotyrosine (JAK2)9121492;8647880Phospho.ELM 6.0
627Phosphotyrosine (JAK2)9121492;8647880Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr5

Promoter: 42458283 - 42460283Agilent_014791

chr5

Promoter: 42458283 - 42460283GSE27584

chr5

Promoter: 42458283 - 42460283Agilent_014791_44K