| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2690 |
Name | GHR |
Synonymous | growth hormone receptor;GHR;growth hormone receptor |
Definition | GH receptor|growth hormone binding protein|serum binding protein|somatotropin receptor |
Position | 5p13-p12 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | GHR(h) + ATP --> GHR(h){pY} + ADP (phosphorylation) | Jak2(h){pY} + GHR(h) <==> Jak2(h){pY}:GHR(h) (binding) | STAT5(h) + GHR(h) <==> STAT5(h):GHR(h) (binding) | GHR(h) --> GHR(h) (expression). | GHR(h) --> GHR(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 46 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 115 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 156 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 161 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 200 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 332 | Phosphotyrosine (JAK2) | 9121492 | Phospho.ELM 6.0 | 487 | Phosphotyrosine (JAK2) | 9121492 | Phospho.ELM 6.0 | 534 | Phosphotyrosine (JAK2) | 9121492;8647880 | Phospho.ELM 6.0 | 566 | Phosphotyrosine (JAK2) | 9121492;8647880 | Phospho.ELM 6.0 | 627 | Phosphotyrosine (JAK2) | 9121492;8647880 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr5 |
Promoter: 42458283 - 42460283 | Agilent_014791 |
chr5 |
Promoter: 42458283 - 42460283 | GSE27584 |
chr5 |
Promoter: 42458283 - 42460283 | Agilent_014791_44K |