| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2690 |
Name | GHR |
Synonym | GHBP|GHIP;growth hormone receptor;GHR;growth hormone receptor |
Definition | GH receptor|growth hormone binding protein|serum binding protein|somatotropin receptor |
Position | 5p13-p12 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | Neuroactive ligand-receptor interaction;KEGG PATHWAY;hsa04080 |
Pathway | growth hormone signaling pathway;PID BioCarta;100155 |
Pathway | Notch-mediated HES/HEY network;PID Curated;200196 |
Pathway | mtor signaling pathway;PID BioCarta;100101 |
Pathway | akt signaling pathway;PID BioCarta;100245 |
Pathway | trefoil factors initiate mucosal healing;PID BioCarta;100018 |
Pathway | regulation of eif-4e and p70s6 kinase;PID BioCarta;100178 |
Disease | HEMATOLOGICAL;GAD |
Disease | Lung cancer;FunDO |
Disease | grow intrauterine growth;GAD |
Disease | Increased responsiveness to growth hormone;OMIM |
Disease | Breast cancer;FunDO |
Disease | DEVELOPMENTAL;GAD |
Disease | growth hormone concentrations insulin-like growth factor;GAD |
Disease | Embryoma;FunDO |
Disease | Prostate cancer;FunDO |
Disease | IMMUNE;GAD |
Disease | small-for-gestational-age;GAD |
Disease | mandibular height;GAD |
Disease | PHARMACOGENOMIC;GAD |
Disease | cholesterol height;GAD |
Disease | Stroke;FunDO |
Disease | systemic lupus erythematosus;GAD |
Disease | serum markers of iron status;GAD |
Disease | METABOLIC;GAD |
Disease | Hypercholesterolemia, familial, modification of;OMIM |
Disease | Diabetes mellitus;FunDO |
Disease | Adenoma;FunDO |
Disease | REPRODUCTION;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | diabetes, type 2 metabolism syndrome;GAD |
Disease | Serum markers of iron status;NHGRI |
Disease | Hypertension;FunDO |
Disease | growth hormone responsiveness;GAD |
Disease | Acromegaly;GAD |
Disease | growth response to growth hormone therapy;GAD |
Disease | Laron dwarfism;OMIM |
Disease | Short stature, idiopathic;OMIM |
Disease | Pituitary tumor;FunDO |
Disease | Congenital abnormality;FunDO |
Disease | Acromegaly;FunDO |
Disease | Systemic lupus erythematosus;NHGRI |
Disease | blood pressure, arterial hypertension;GAD |
External Links | |
Links to Entrez Gene | 2690 |
Links to all GeneRIF Items | 2690 |
Links to iHOP | 2690 |
Sequence Information | |
Nucleotide Sequence | >2690 : length: 4814 GGAGAGACTGGGGAGGTCGAGCTGTGCGCGTGGACACAGCGCGCAGAGCGCGCGGTCTTT TGCGCGTTTGTGCGGGCCGCAGCCGCACGTTGGCACCGATGGAACTGGGGTCAGTAGAGT GACAGCCACCAGTCCGCATGAACTGGGTTAAAATGAGCAACTTCTTTAACCAGAACTGAC CTTGAAGACAAATGGCTAAAATAAAACATTTGCTGAATTCACTGGGCGCATCTTACAAGT AATTTTTGGATTCTGCATTGACTACCTACAAGTGCCTTCTGGGTGCAAGTCCACAGGCAA GATTTGTTCTGCAAATCTTCCATGACCAAGGTCACCTCTTTGGATTGGCAGACCCAGGGA GTCCATATTGGGAAGATAAATTCACACTTCACCCCTTGTTGAGATCTCCAGCCTTGCTCC TCTGATAACCAGGTCCTACAGGTATGGATCTCTGGCAGCTGCTGTTGACCTTGGCACTGG CAGGATCAAGTGATGCTTTTTCTGGAAGTGAGGCCACAGCAGCTATCCTTAGCAGAGCAC CCTGGAGTCTGCAAAGTGTTAATCCAGGCCTAAAGACAAATTCTTCTAAGGAGCCTAAAT TCACCAAGTGCCGTTCACCTGAGCGAGAGACTTTTTCATGCCACTGGACAGATGAGGTTC ATCATGGTACAAAGAACCTAGGACCCATACAGCTGTTCTATACCAGAAGGAACACTCAAG AATGGACTCAAGAATGGAAAGAATGCCCTGATTATGTTTCTGCTGGGGAAAACAGCTGTT ACTTTAATTCATCGTTTACCTCCATCTGGATACCTTATTGTATCAAGCTAACTAGCAATG GTGGTACAGTGGATGAAAAGTGTTTCTCTGTTGATGAAATAGTGCAACCAGATCCACCCA TTGCCCTCAACTGGACTTTACTGAACGTCAGTTTAACTGGGATTCATGCAGATATCCAAG TGAGATGGGAAGCACCACGCAATGCAGATATTCAGAAAGGATGGATGGTTCTGGAGTATG AACTTCAATACAAAGAAGTAAATGAAACTAAATGGAAAATGATGGACCCTATATTGACAA CATCAGTTCCAGTGTACTCATTGAAAGTGGATAAGGAATATGAAGTGCGTGTGAGATCCA AACAACGAAACTCTGGAAATTATGGCGAGTTCAGTGAGGTGCTCTATGTAACACTTCCTC AGATGAGCCAATTTACATGTGAAGAAGATTTCTACTTTCCATGGCTCTTAATTATTATCT TTGGAATATTTGGGCTAACAGTGATGCTATTTGTATTCTTATTTTCTAAACAGCAAAGGA TTAAAATGCTGATTCTGCCCCCAGTTCCAGTTCCAAAGATTAAAGGAATCGATCCAGATC TCCTCAAGGAAGGAAAATTAGAGGAGGTGAACACAATCTTAGCCATTCATGATAGCTATA AACCCGAATTCCACAGTGATGACTCTTGGGTTGAATTTATTGAGCTAGATATTGATGAGC CAGATGAAAAGACTGAGGAATCAGACACAGACAGACTTCTAAGCAGTGACCATGAGAAAT CACATAGTAACCTAGGGGTGAAGGATGGCGACTCTGGACGTACCAGCTGTTGTGAACCTG ACATTCTGGAGACTGATTTCAATGCCAATGACATACATGAGGGTACCTCAGAGGTTGCTC AGCCACAGAGGTTAAAAGGGGAAGCAGATCTCTTATGCCTTGACCAGAAGAATCAAAATA ACTCACCTTATCATGATGCTTGCCCTGCTACTCAGCAGCCCAGTGTTATCCAAGCAGAGA AAAACAAACCACAACCACTTCCTACTGAAGGAGCTGAGTCAACTCACCAAGCTGCCCATA TTCAGCTAAGCAATCCAAGTTCACTGTCAAACATCGACTTTTATGCCCAGGTGAGCGACA TTACACCAGCAGGTAGTGTGGTCCTTTCCCCGGGCCAAAAGAATAAGGCAGGGATGTCCC AATGTGACATGCACCCGGAAATGGTCTCACTCTGCCAAGAAAACTTCCTTATGGACAATG CCTACTTCTGTGAGGCAGATGCCAAAAAGTGCATCCCTGTGGCTCCTCACATCAAGGTTG AATCACACATACAGCCAAGCTTAAACCAAGAGGACATTTACATCACCACAGAAAGCCTTA CCACTGCTGCTGGGAGGCCTGGGACAGGAGAACATGTTCCAGGTTCTGAGATGCCTGTCC CAGACTATACCTCCATTCATATAGTACAGTCCCCACAGGGCCTCATACTCAATGCGACTG CCTTGCCCTTGCCTGACAAAGAGTTTCTCTCATCATGTGGCTATGTGAGCACAGACCAAC TGAACAAAATCATGCCTTAGCCTTTCTTTGGTTTCCCAAGAGCTACGTATTTAATAGCAA AGAATTGACTGGGGCAATAACGTTTAAGCCAAAACAATGTTTAAACCTTTTTTGGGGGAG TGACAGGATGGGGTATGGATTCTAAAATGCCTTTTCCCAAAATGTTGAAATATGATGTTA AAAAAATAAGAAGAATGCTTAATCAGATAGATATTCCTATTGTGCAATGTAAATATTTTA AAGAATTGTGTCAGACTGTTTAGTAGCAGTGATTGTCTTAATATTGTGGGTGTTAATTTT TGATACTAAGCATTGAATGGCTATGTTTTTAATGTATAGTAAATCACGCTTTTTGAAAAA GCGAAAAAATCAGGTGGCTTTTGCGGTTCAGGAAAATTGAATGCAAACCATAGCACAGGC TAATTTTTTGTTGTTTCTTAAATAAGAAACTTTTTTATTTAAAAAACTAAAAACTAGAGG TGAGAAATTTAAACTATAAGCAAGAAGGCAAAAATAGTTTGGATATGTAAAACATTTATT TTGACATAAAGTTGATAAAGATTTTTTAATAATTTAGACTTCAAGCATGGCTATTTTATA TTACACTACACACTGTGTACTGCAGTTGGTATGACCCCTCTAAGGAGTGTAGCAACTACA GTCTAAAGCTGGTTTAATGTTTTGGCCAATGCACCTAAAGAAAAACAAACTCGTTTTTTA CAAAGCCCTTTTATACCTCCCCAGACTCCTTCAACAATTCTAAAATGATTGTAGTAATCT GCATTATTGGAATATAATTGTTTTATCTGAATTTTTAAACAAGTATTTGTTAATTTAGAA AACTTTAAAGCGTTTGCACAGATCAACTTACCAGGCACCAAAAGAAGTAAAAGCAAAAAA GAAAACCTTTCTTCACCAAATCTTGGTTGATGCCAAAAAAAAATACATGCTAAGAGAAGT AGAAATCATAGCTGGTTCACACTGACCAAGATACTTAAGTGCTGCAATTGCACGCGGAGT GAGTTTTTTAGTGCGTGCAGATGGTGAGAGATAAGATCTATAGCCTCTGCAGCGGAATCT GTTCACACCCAACTTGGTTTTGCTACATAATTATCCAGGAAGGGAATAAGGTACAAGAAG CATTTTGTAAGTTGAAGCAAATCGAATGAAATTAACTGGGTAATGAAACAAAGAGTTCAA GAAATAAGTTTTTGTTTCACAGCCTATAACCAGACACATACTCATTTTTCATGATAATGA ACAGAACATAGACAGAAGAAACAAGGTTTTCAGTCCCCACAGATAACTGAAAATTATTTA AACCGCTAAAAGAAACTTTCTTTCTCACTAAATCTTTTATAGGATTTATTTAAAATAGCA AAAGAAGAAGTTTCATCATTTTTTACTTCCTCTCTGAGTGGACTGGCCTCAAAGCAAGCA TTCAGAAGAAAAAGAAGCAACCTCAGTAATTTAGAAATCATTTTGCAATCCCTTAATATC CTAAACATCATTCATTTTTGTTGTTGTTGTTGTTGTTGAGACAGAGTCTCGCTCTGTCGC CAGGCTAGAGTGCGGTGGCGCGATCTTGACTCACTGCAATCTCCACCTCCCACAGGTTCA GGCGATTCCCGTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCACGCACCACCATGCC AGGCTAATTTTTTTGTATTTTAGCAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCT CGATCTCCTGACCTCGTGATCCACCCGACTCGGCCTCCCAAAGTGCTGGGATTACAGGTG TAAGCCACCGTGCCCAGCCCTAAACATCATTCTTGAGAGCATTGGGATATCTCCTGAAAA GGTTTATGAAAAAGAAGAATCTCATCTCAGTGAAGAATACTTCTCATTTTTTAAAAAAGC TTAAAACTTTGAAGTTAGCTTTAACTTAAATAGTATTTCCCATTTATCGCAGACCTTTTT TAGGAAGCAAGCTTAATGGCTGATAATTTTAAATTCTCTCTCTTGCAGGAAGGACTATGA AAAGCTAGAATTGAGTGTTTAAAGTTCAACATGTTATTTGTAATAGATGTTTGATAGATT TTCTGCTACTTTGCTGCTATGGTTTTCTCCAAGAGCTACATAATTTAGTTTCATATAAAG TATCATCAGTGTAGAACCTAATTCAATTCAAAGCTGTGTGTTTGGAAGACTATCTTACTA TTTCACAACAGCCTGACAACATTTCTATAGCCAAAAATAGCTAAATACCTCAATCAGTCT CAGAATGTCATTTTGGTACTTTGGTGGCCACATAAGCCATTATTCACTAGTATGACTAGT TGTGTCTGGCAGTTTATATTTAACTCTCTTTATGTCTGTGGATTTTTTCCTTCAAAGTTT AATAAATTTATTTTCTTGGATTCCTGATAGTGTGCTTCTGTTATCAAACACCAACATAAA AATGATCTAAACCA |
Protein Sequence | >2690 : length: 645 MNWGPTGMDLWQLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKF TKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCY FNSSFTSIWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQV RWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSK QRNSGNYGEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRI KMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEP DEKTEESDTDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQ PQRLKGEADLLCLDQKNQNNSPYHDACPATQQPSVIQAEKNKPQPLPTEGAESTHQAAHI QLSNPSSLSNIDFYAQVSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVSLCQENFLMDNA YFCEADAKKCIPVAPHIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVP DYTSIHIVQSPQGLILNATALPLPDKEFLSSCGYVSTDQLNKIMP |