| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2690 |
Name | GHR |
Synonymous | growth hormone receptor;GHR;growth hormone receptor |
Definition | GH receptor|growth hormone binding protein|serum binding protein|somatotropin receptor |
Position | 5p13-p12 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
JAK2 | REACTOME; |
in same component |
LYN | REACTOME; |
in same component |
PTPN1 | REACTOME; |
in same component |
PTPN6 | REACTOME; |
interacts with |
AP2A1 | HPRD; |
interacts with |
BTRC | BIOGRID; |
interacts with |
CISH | BIOGRID; |
interacts with |
CISH | HPRD; |
interacts with |
CRK | MINT; |
interacts with |
DUSP7 | BIOGRID; |
interacts with |
DUSP7 | MINT; |
interacts with |
GH1 | BIOGRID; |
interacts with |
GRB10 | BIOGRID; |
interacts with |
GRB10 | HPRD; |
interacts with |
IRS1 | HPRD; |
interacts with |
JAK1 | BIOGRID; |
interacts with |
JAK1 | HPRD; |
interacts with |
JAK2 | BIOGRID; |
interacts with |
JAK2 | HPRD; |
interacts with |
NCK1 | MINT; |
interacts with |
NCOA6 | HPRD; |
interacts with |
PIK3R1 | BIOGRID; |
interacts with |
PIK3R1 | HPRD; |
interacts with |
PIK3R1 | MINT; |
interacts with |
PLCG1 | BIOGRID; |
interacts with |
PLCG1 | MINT; |
interacts with |
PRLR | HPRD; |
interacts with |
PSAP | MINT; |
interacts with |
PTPN11 | BIOGRID; |
interacts with |
PTPN11 | HPRD; |
interacts with |
PTPN13 | BIOGRID; |
interacts with |
PTPN1 | BIOGRID; |
interacts with |
PTPN1 | MINT; |
interacts with |
PTPN2 | BIOGRID; |
interacts with |
PTPN2 | MINT; |
interacts with |
PTPN3 | BIOGRID; |
interacts with |
PTPN3 | MINT; |
interacts with |
PTPN6 | HPRD; |
interacts with |
PTPN9 | BIOGRID; |
interacts with |
PTPN9 | MINT; |
interacts with |
PTPRB | BIOGRID; |
interacts with |
PTPRB | MINT; |
interacts with |
PTPRH | BIOGRID; |
interacts with |
SGTA | BIOGRID; |
interacts with |
SGTA | HPRD; |
interacts with |
SHC1 | BIOGRID; |
interacts with |
SHC1 | HPRD; |
interacts with |
SOCS1 | BIOGRID; |
interacts with |
SOCS1 | HPRD; |
interacts with |
SOCS2 | BIOGRID; |
interacts with |
SOCS2 | HPRD; |
interacts with |
SOCS2 | MINT; |
interacts with |
SOCS3 | BIOGRID; |
interacts with |
SOCS3 | HPRD; |
interacts with |
STAT3 | BIOGRID; |
interacts with |
STAT3 | HPRD; |
interacts with |
STAT5A | HPRD; |
interacts with |
STAT5B | BIOGRID; |
interacts with |
STAT5B | HPRD; |
interacts with |
TYK2 | BIOGRID; |
interacts with |
TYK2 | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
HES1 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
GHR | REACTOME; |
reacts with |
JAK2 | REACTOME; |
reacts with |
LYN | REACTOME; |
reacts with |
PTPN1 | REACTOME; |
reacts with |
PTPN6 | REACTOME; |
state change |
ADAM17 | REACTOME; |
state change |
GHR | REACTOME; |
state change |
JAK2 | REACTOME; |
state change |
PTPN1 | REACTOME; |
state change |
PTPN6 | REACTOME; |