| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 219699 |
Name | UNC5B |
Synonymous | unc-5 homolog B (C. elegans);UNC5B;unc-5 homolog B (C. elegans) |
Definition | netrin receptor UNC5B|p53-regulated receptor for death and life protein 1|protein unc-5 homolog 2|protein unc-5 homolog B|transmembrane receptor Unc5H2|unc-5 homolog 2 |
Position | 10q22.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | PIKE(m.s.) + unc-5B-isoform1(h) <==> PIKE(m.s.):unc-5B-isoform1(h) (binding) | unc-5B-isoform1(h) + ATP --> unc-5B-isoform1(h){pY} + ADP (phosphorylation) | UNC5B(h) --> unc-5B-isoform1(h) (expression). | G-alpha-i2(m) + unc-5B(h) <==> G-alpha-i2(m):unc-5B(h) (binding) | unc-5B(h) + G-alpha-i2(m):GTP <==> unc-5B(h):G-alpha-i2(m):GTP (binding) | unc-5B(h) + PIKE(m.s.) <==> unc-5B(h):PIKE(m.s.) (binding) | UNC5B(h) --> unc-5B(h) (expression). | UNC5B(h) --> unc-5B-isoform2(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 222 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 347 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr10 |
Promoter: 72640855 - 72642855 | Agilent_014791 |
chr10 |
Promoter: 72640855 - 72642855 | GSE27584 |
chr10 |
Promoter: 72640855 - 72642855 | Agilent_014791_44K |