| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 219699 |
Name | UNC5B |
Synonym | UNC5H2|p53RDL1;unc-5 homolog B (C. elegans);UNC5B;unc-5 homolog B (C. elegans) |
Definition | netrin receptor UNC5B|p53-regulated receptor for death and life protein 1|protein unc-5 homolog 2|protein unc-5 homolog B|transmembrane receptor Unc5H2|unc-5 homolog 2 |
Position | 10q22.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Apoptosis;Reactome;REACT:578 |
Pathway | Axon guidance mediated by netrin;PANTHER;P00009 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Netrin-1 signaling;PID Reactome;500088 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Role of DCC in regulating apoptosis;PID Reactome;500280 |
Pathway | Netrin-mediated signaling;PID Curated;200074 |
Disease | PSYCH;GAD |
Disease | attention-deficit hyperactivity disorder;GAD |
Disease | Cancer;FunDO |
Disease | ADHD;GAD |
Disease | Attention deficit hyperactivity disorder;NHGRI |
External Links | |
Links to Entrez Gene | 219699 |
Links to all GeneRIF Items | 219699 |
Links to iHOP | 219699 |
Sequence Information | |
Nucleotide Sequence | >219699 : length: 6941 GAACTCACTCCGGCGAGCGAGCGGCGGCGCTCGGCATTGTGGCAGGCGGCTGGGGCCGGC TAGGGCGCCGGAGCCGCACGCAGCCGCGGGGCTCCGAGAGGCGCGCACTGGGGCTGGGAC TGCGCGGCGCCGCCGCTGCGAGCGCCACTGAGCGGTCGCGCAACTTCGGAGGCACAGCGC CGGAGCCAGGCGAGCGCTCAGAGACCCGGAGCCAGAGGGGCGCGCCGGAGCCTCGTTCGA GAGCCGGCGCCAGGCACCCACCGCGCTCCGAGTGCCAGGCGGCCCTCCGCGCAGCGTGGC TTCCGCTGCCCCCACGGAAGGCACGGGCTGGCGCTGCCGGGCGCCGGGGAGGACGGCGAG GAGGAGGCGGCGGCGGCGGAGACGGCGGCGGCGAGACTGGGGCCAGGGAGACAGCCCTGG GGGAGAGGCGCCCGAACCAGGCCGCGGGAGCATGGGGGCCCGGAGCGGAGCTCGGGGCGC GCTGCTGCTGGCACTGCTGCTCTGCTGGGACCCGAGGCTGAGCCAAGCAGGCACTGATTC TGGCAGCGAGGTGCTCCCTGACTCCTTCCCGTCAGCGCCAGCAGAGCCGCTGCCCTACTT CCTGCAGGAGCCACAGGACGCCTACATTGTGAAGAACAAGCCTGTGGAGCTCCGCTGCCG CGCCTTCCCCGCCACACAGATCTACTTCAAGTGCAACGGCGAGTGGGTCAGCCAGAACGA CCACGTCACACAGGAAGGCCTGGATGAGGCCACCGGCCTGCGGGTGCGCGAGGTGCAGAT CGAGGTGTCGCGGCAGCAGGTGGAGGAGCTCTTTGGGCTGGAGGATTACTGGTGCCAGTG CGTGGCCTGGAGCTCCGCGGGCACCACCAAGAGTCGCCGAGCCTACGTCCGCATCGCCTA CCTGCGCAAGAACTTCGATCAGGAGCCTCTGGGCAAGGAGGTGCCCCTGGACCATGAGGT TCTCCTGCAGTGCCGCCCGCCGGAGGGGGTGCCTGTGGCCGAGGTGGAATGGCTCAAGAA TGAGGATGTCATCGACCCCACCCAGGACACCAACTTCCTGCTCACCATCGACCACAACCT CATCATCCGCCAGGCCCGCCTGTCGGACACTGCCAACTATACCTGCGTGGCCAAGAACAT CGTGGCCAAACGCCGGAGCACCACTGCCACCGTCATCGTCTACGTGAATGGCGGCTGGTC CAGCTGGGCAGAGTGGTCACCCTGCTCCAACCGCTGTGGCCGAGGCTGGCAGAAGCGCAC CCGGACCTGCACCAACCCCGCTCCACTCAACGGAGGGGCCTTCTGCGAGGGCCAGGCATT CCAGAAGACCGCCTGCACCACCATCTGCCCAGTCGATGGGGCGTGGACGGAGTGGAGCAA GTGGTCAGCCTGCAGCACTGAGTGTGCCCACTGGCGTAGCCGCGAGTGCATGGCGCCCCC ACCCCAGAACGGAGGCCGTGACTGCAGCGGGACGCTGCTCGACTCTAAGAACTGCACAGA TGGGCTGTGCATGCAAAATAAGAAAACTCTAAGCGACCCCAACAGCCACCTGCTGGAGGC CTCAGGGGATGCGGCGCTGTATGCGGGGCTCGTGGTGGCCATCTTCGTGGTCGTGGCAAT CCTCATGGCGGTGGGGGTGGTGGTGTACCGCCGCAACTGCCGTGACTTCGACACAGACAT CACTGACTCATCTGCTGCCCTGACTGGTGGTTTCCACCCCGTCAACTTTAAGACGGCAAG GCCCAGCAACCCGCAGCTCCTACACCCCTCTGTGCCTCCTGACCTGACAGCCAGCGCCGG CATCTACCGCGGACCCGTGTATGCCCTGCAGGACTCCACCGACAAAATCCCCATGACCAA CTCTCCTCTGCTGGACCCCTTACCCAGCCTTAAGGTCAAGGTCTACAGCTCCAGCACCAC GGGCTCTGGGCCAGGCCTGGCAGATGGGGCTGACCTGCTGGGGGTCTTGCCGCCTGGCAC ATACCCTAGCGATTTCGCCCGGGACACCCACTTCCTGCACCTGCGCAGCGCCAGCCTCGG TTCCCAGCAGCTCTTGGGCCTGCCCCGAGACCCAGGGAGCAGCGTCAGCGGCACCTTTGG CTGCCTGGGTGGGAGGCTCAGCATCCCCGGCACAGGGGTCAGCTTGCTGGTGCCCAATGG AGCCATTCCCCAGGGCAAGTTCTACGAGATGTATCTACTCATCAACAAGGCAGAAAGTAC CCTCCCGCTTTCAGAAGGGACCCAGACAGTATTGAGCCCCTCGGTGACCTGTGGACCCAC AGGCCTCCTGCTGTGCCGCCCCGTCATCCTCACCATGCCCCACTGTGCCGAAGTCAGTGC CCGTGACTGGATCTTTCAGCTCAAGACCCAGGCCCACCAGGGCCACTGGGAGGAGGTGGT GACCCTGGATGAGGAGACCCTGAACACACCCTGCTACTGCCAGCTGGAGCCCAGGGCCTG TCACATCCTGCTGGACCAGCTGGGCACCTACGTGTTCACGGGCGAGTCCTATTCCCGCTC AGCAGTCAAGCGGCTCCAGCTGGCCGTCTTCGCCCCCGCCCTCTGCACCTCCCTGGAGTA CAGCCTCCGGGTCTACTGCCTGGAGGACACGCCTGTAGCACTGAAGGAGGTGCTGGAGCT GGAGCGGACTCTGGGCGGATACTTGGTGGAGGAGCCGAAACCGCTAATGTTCAAGGACAG TTACCACAACCTGCGCCTCTCCCTCCATGACCTCCCCCATGCCCATTGGAGGAGCAAGCT GCTGGCCAAATACCAGGAGATCCCCTTCTATCACATTTGGAGTGGCAGCCAGAAGGCCCT CCACTGCACTTTCACCCTGGAGAGGCACAGCTTGGCCTCCACAGAGCTCACCTGCAAGAT CTGCGTGCGGCAAGTGGAAGGGGAGGGCCAGATATTCCAGCTGCATACCACTCTGGCAGA GGTGAGGGAAGTCGGGGCCACATATTCCAGCTGCACACCACACTGGCGGAGACACCTGCT GGCTCCCTGGACACTCTCTGCTCTGCCCCTGGCAGCACTGTCACCACCCAGCTGGGACCT TATGCCTTCAAGATCCCACTGTCCATCCGCCAGAAGATATGCAACAGCCTAGATGCCCCC AACTCACGGGGCAATGACTGGCGGATGTTAGCACAGAAGCTCTCTATGGACCGGTACCTG AATTACTTTGCCACCAAAGCGAGCCCCACGGGTGTGATCCTGGACCTCTGGGAAGCTCTG CAGCAGGACGATGGGGACCTCAACAGCCTGGCGAGTGCCTTGGAGGAGATGGGCAAGAGT GAGATGCTGGTGGCTGTGGCCACCGACGGGGACTGCTGAGCCTCCTGGGACAGCGGGCTG GCAGGGACTGGCAGGAGGCAGGTGCAGGGAGGCCTGGGGCAGCCTCCTGATGGGGATGTT TGGCCTCTGCTTCCTCCCAGTTCACAGCCAGAGTTGCCTCTCCTCCTCCTCTTCCCCAAC CCCCAGACCATGACCAGCCTTAGAAAATCCATGTACTCTGTTGTTAGAGGGCCCAGAGTT CCTTCTCCACCCCCGCTCTCTCTCTCTTGGCCTGAGATCTCTGTGCAGGAACCAAGATGG GGCTGAAGCCTCTGGAGGCAGTTGGTTGGGGGCGGGCAGGCAGGAGGCCCTCCCTCCACC CCCCCACCCTCAGCCCGGCAACTTCTGGGTTCCATGGGTTTTAGTTCCGTTCTCGTTTTC TTCCTCCGTTATTGATTTCTCCTTTCTCCCTAAGCCCCCTTCTGCTTCCACGCCCTTTTC CTCTTTGAAGAGTCAAGTACAATTCAGACAAACTGCTTTCTCCTGTCCAAAAGCAAAAAG GCAAAGGAAAGAAAGAAAGCTTCAGACCGCTAGTAAGGCTCAAAGAAGAAGAAAAACACC AAAACCACAAGGGAAAAGAAAAACCCAGTTTCTTAGGAAACGCAAACGATTTATTATCCA GATTATTTGGATAAGTCCTTTTTAAGAAAAAAAAAGAAAATGAAAAACAACACAAAAAAA ATAGAAAACTCTTTTCTTGAGTGTGGATGAGAATGGGCACGCTCACACTTCTGGCCAGGA GTGAATGTGCCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTACATGTACGCGTGTGC ATTGAGGAGAGAGAGACTGAACAGAGAGTACTTTGCTGCTAACGAATCCATCTTGGACTA AATTCTGACAAGGCCTCAGTTTCCCCAGTTGTGCAGGGAGTAGGTCAGACAGGGTTTTCA CTGTCTAGATTTAGCTGGTTAGATTTTCCTCTAAAATCTTAAGCAGATGCTGAATCCATA AAGCCAAGGAGTGCTGAGGGCTGGAGTGGGTGGGCCCTCCCTCCCACAGCCCCAGGGAGA TACATCTGGACTCCTGGGAATCTGGATTAAGAAAGTTGGGATGAAAGAGGAGGACTGCTC AGGCCAGTTGTGAGCCAGGGAGAATGTTCCAGTCTGGTTTTGGTCTGGTGGCTCCTAGAA AGGGATGTGGCCCAGAAGTGGGACTCAAACAGAGAGATGAAGTAGGGGAGGGGAGTCCTC CACGGGCATCTCTCTCCTGGCGGCTGGATAGCTTTACCCTAGGGTGGGGCCAGCCCTGAC ACCCTCATCCCCTCCTCAGCCCAGCAGCCTCTAGAGCAGCGTGGTGCTCTCTTGATGGCC AGGAATCCAGAATCTGCCCTTCCCCAACCTTGGTTTCTCCTTCTGTAAAGCAGAGTGATG GCTGAGAAGTCCTCTCTAGCTGCAGAAGCCTGAGCTTCCCGGTGTCAGTCAGCTCTGCAA CGTGGGAGCCTTGGAGGCGGGTGGCCTGGCTGTGCTTCATATGCCCAGGAGTGGAGAAGG AGGCTGAGAAGCTGGTTTCCCAGCTCTGATCTCCACAGGCACCTCCTATAACCCTCCTCT CACCCACCCCGCTACGGTCTGAGAGATCTGAAATAACCTTTCCCAGTGGGCAGGGTTGCC AGGGTTGAGGGGACAGCACATACCACCCCCACCCAACCTGTTCGAGGGGCCCTGCATGGC ACGGGATGAGTCCCTGCCCTGTGCAGCTGCCTGGCAGTGGCTGGGACAAGGATCTTGCAG CCAGCACAGAGGCCTCTTCAAAGGCCTCTCCCTCTTGGCACTCCAGGCAAGGCAGGTGCC CGCTTCCCCAACACCTCCAGGCAGTGACCCTAGGGCATGCCCCAGCAGGTCTCCGAGCAG CCACTGGGACCCGTCTCAGCACATCCTGGCCTTTGAAAGTCTGATATCCTGAGAGGAGGG CAGGTTTTAGGGCCGCAGTTCCAGCCAGCGTCCCCAGCCTGGCTTCCCTGCCATGGACTC AGTAGCTCGTGGGGCTTCTTACCACCCACCAGCCCCGCTGGGGTGCGGCCTGGCTGTGGG CAAAGGAGGACTTGCCTGGAGATTTGAGAGAAGATTCCTTCTACCAGGGCTGCTGAGGGG CCAGGCCTGCATCAGGGGCTAGGCTCTGGCTGGGCCCGGAGGCTGAGACTAAGGCTTTCG ACCCTGGTGCCTCCATGTGGATGCTGCCTCAGACAAAGGCAGTGAGCCTTCCCTGCCAAA GTGCCCATCCCATGGGCTCGGCCTCACTGGTCACTGTTAGCCCATGAACACGTGTGGGCC TCGGTCACGTGGCTTTGAGGGCAGTCTGACCAGGCTAGACCACACGTGCCGTGACAGGGG GTGCCATTCCCCTCGCAGGCTCTAATGTGCCCACATGTAGCCTGGCAGTCCAAAGACCAA GAATCAACTTGCAAATCTGCCATTAAACTGCTGTGCGACTTCAGGCATATCACTGCCTTC TCTGGGCTTCAGTGTCCTTTTCATACCTAGAAGTCTGCGGTCTGAGGCTCTTTGGGTTCA GACACACTGTTCTAGGCTTCTGTAGGGGACCTTGTGATCTGCCGTGCCCCTCCTCCCTGT TCTTTTCTGTCCTCCCCACCCCACCCTCAGAAGCTGCTTGCTCTGCCCCCAGGACAGGAG CTTGACGGATGAAGTGCAGCCAGCCACCCAGGTGCCATTTCCAGTCTGACTTCCAGAAAT GTGCACCATGTCCTAGAGCACAGACCCATTGGCTGGAGCCTCCTGGGAGGGTTCAAACCA TCAGCTCTATGAGAAATGCCCAGAAAGGCTTTGCCGACTCCATCCGTCTGTGGAGGCTGC CTGCCTCCGGGGTGGGATGGGTGGTTTCTCCTCCAATTCAGACCCAAGAGGTAGCCCCCG AGGGCATGTACCTGGTGGGAAGCAGCTCAGGTACCCTTGGGGGTTGCAGGGCCCTTACGC AGGTATTTCTCTCTCTCTCCTCTCTGGGGTGCGTGTGTGCGTGCGCGTGTGCGTGCCTAT GCTTTTCTCTGTGGGCACATCAGGATGCCCCTCGGAGAGCATGTGCACGTGTCCCCACCT GAGCGAGCGTGTGTGTGTGCTCCTCTGCGTCCCAGGTTTGGACGTCTAGGGTTTGGTGTG CCTGTCTTCTGCCCTCCCTGAGCCCACAGGGTCAGTCAATGTATCTTCTACGTGCCTCTC CCTCTGCCTTCTCTCACAGTGCCCCCGGCTCCAGAGCTCAGGGGTAGGGGTTCTCCTGAG GGTGCAGGGGATCCTTCTCATCTCCTGGACCCTCCAGGGCACTCTGGTCCCTATTCCCCA GCTCCTAGGCAGCTGAGCCGGGTCCCTTAGGGGAGGTGACCAGGAGCTTTGGTGCAGGGA GCTCTTGGTGGGGCAAAGGGCTGGACCCCTGCCAGGTCTGTGGACATGGTTATATGCCCG GGAGAGGGGGGTGCAGGGCCCCAGGGATGGCCCCCAATCCCACCTCTGTTTATTCTGTAA ACTGCAACCTATAAATAACCTTTAGCATTCCTATTGTAACAAAATTAATTTTTATGAAAT AAATTATATTTCCTAGTCTAATAAAATCCGGGTTGCATTTG |
Protein Sequence | >219699 : length: 945 MGARSGARGALLLALLLCWDPRLSQAGTDSGSEVLPDSFPSAPAEPLPYFLQEPQDAYIV KNKPVELRCRAFPATQIYFKCNGEWVSQNDHVTQEGLDEATGLRVREVQIEVSRQQVEEL FGLEDYWCQCVAWSSAGTTKSRRAYVRIAYLRKNFDQEPLGKEVPLDHEVLLQCRPPEGV PVAEVEWLKNEDVIDPTQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTAT VIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTICP VDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQNKKTL SDPNSHLLEASGDAALYAGLVVAIFVVVAILMAVGVVVYRRNCRDFDTDITDSSAALTGG FHPVNFKTARPSNPQLLHPSVPPDLTASAGIYRGPVYALQDSTDKIPMTNSPLLDPLPSL KVKVYSSSTTGSGPGLADGADLLGVLPPGTYPSDFARDTHFLHLRSASLGSQQLLGLPRD PGSSVSGTFGCLGGRLSIPGTGVSLLVPNGAIPQGKFYEMYLLINKAESTLPLSEGTQTV LSPSVTCGPTGLLLCRPVILTMPHCAEVSARDWIFQLKTQAHQGHWEEVVTLDEETLNTP CYCQLEPRACHILLDQLGTYVFTGESYSRSAVKRLQLAVFAPALCTSLEYSLRVYCLEDT PVALKEVLELERTLGGYLVEEPKPLMFKDSYHNLRLSLHDLPHAHWRSKLLAKYQEIPFY HIWSGSQKALHCTFTLERHSLASTELTCKICVRQVEGEGQIFQLHTTLAETPAGSLDTLC SAPGSTVTTQLGPYAFKIPLSIRQKICNSLDAPNSRGNDWRMLAQKLSMDRYLNYFATKA SPTGVILDLWEALQQDDGDLNSLASALEEMGKSEMLVAVATDGDC |