Entrez Gene

Basic Information
Gene ID	219699
Name	UNC5B
Synonymous	unc-5 homolog B (C. elegans);UNC5B;unc-5 homolog B (C. elegans)
Definition	netrin receptor UNC5B\|p53-regulated receptor for death and life protein 1\|protein unc-5 homolog 2\|protein unc-5 homolog B\|transmembrane receptor Unc5H2\|unc-5 homolog 2
Position	10q22.1
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1735G>A; p.E579K; 10:71292517-71292517	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.684G>C; p.K228N; 10:71286820-71286820	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.844G>A; p.G282R; 10:71287708-71287708	lung; left_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1029C>T; p.L343L; 10:71288695-71288695	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.2088G>T; p.Q696H; 10:71293846-71293846	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1265A>C; p.H422P; 10:71291080-71291080	breast	carcinoma	Substitution - Missense
c.1291C>T; p.P431S; 10:71291106-71291106	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2433C>T; p.C811C; 10:71296685-71296685	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.817T>G; p.C273G; 10:71287681-71287681	central_nervous_system; brain	glioma	Substitution - Missense
c.1121C>T; p.A374V; 10:71290936-71290936	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1621C>A; p.P541T; 10:71291758-71291758	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1621C>A; p.P541T; 10:71291758-71291758	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2415delG; p.E805fs*66; 10:71296667-71296667	skin; neck	malignant_melanoma	Deletion - Frameshift
c.1621C>A; p.P541T; 10:71291758-71291758	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.749_750CC>TT; p.S250F; 10:71287613-71287614	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2101G>A; p.A701T; 10:71293859-71293859	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.428G>A; p.R143Q; 10:71284843-71284843	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2274C>T; p.L758L; 10:71295909-71295909	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.173A>G; p.Y58C; 10:71279914-71279914	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.776C>A; p.S259Y; 10:71287640-71287640	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1290G>A; p.R430R; 10:71291105-71291105	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2176-4A>G; p.?; 10:71295807-71295807	liver	carcinoma	Unknown
c.684G>A; p.K228K; 10:71286820-71286820	thyroid	carcinoma; anaplastic_carcinoma	Substitution - coding silent
c.2176-4A>G; p.?; 10:71295807-71295807	liver	carcinoma	Unknown
c.684G>A; p.K228K; 10:71286820-71286820	thyroid	carcinoma; anaplastic_carcinoma	Substitution - coding silent
c.2094C>G; p.A698A; 10:71293852-71293852	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1284G>C; p.T428T; 10:71291099-71291099	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.351G>A; p.V117V; 10:71284766-71284766	skin	malignant_melanoma	Substitution - coding silent
c.678G>A; p.V226V; 10:71286814-71286814	skin	malignant_melanoma	Substitution - coding silent
c.1847G>A; p.R616H; 10:71293479-71293479	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1811C>T; p.S604L; 10:71293443-71293443	skin	malignant_melanoma	Substitution - Missense
c.262C>T; p.Q88*; 10:71280003-71280003	liver	carcinoma	Substitution - Nonsense
c.829G>A; p.A277T; 10:71287693-71287693	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.829G>A; p.A277T; 10:71287693-71287693	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.758C>T; p.A253V; 10:71287622-71287622	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1545C>T; p.F515F; 10:71291682-71291682	skin	malignant_melanoma	Substitution - coding silent
c.2823C>T; p.T941T; 10:71299262-71299262	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1479G>C; p.G493G; 10:71291616-71291616	breast	carcinoma	Substitution - coding silent
c.2823C>T; p.T941T; 10:71299262-71299262	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1134G>T; p.A378A; 10:71290949-71290949	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2475T>C; p.H825H; 10:71296727-71296727	thyroid	other; neoplasm	Substitution - coding silent
c.1345G>A; p.A449T; 10:71291482-71291482	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.876G>T; p.K292N; 10:71287740-71287740	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2375G>C; p.C792S; 10:71296627-71296627	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.170C>T; p.A57V; 10:71279911-71279911	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2718C>T; p.I906I; 10:71299157-71299157	skin	malignant_melanoma	Substitution - coding silent
c.339G>A; p.S113S; 10:71284754-71284754	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2305A>G; p.K769E; 10:71295940-71295940	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.339G>A; p.S113S; 10:71284754-71284754	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2232G>T; p.P744P; 10:71295867-71295867	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.741C>T; p.G247G; 10:71287605-71287605	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1114G>T; p.G372W; 10:71290929-71290929	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.878C>T; p.T293I; 10:71287742-71287742	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2582C>T; p.S861F; 10:71298000-71298000	skin	malignant_melanoma	Substitution - Missense
c.2100C>T; p.F700F; 10:71293858-71293858	skin	malignant_melanoma	Substitution - coding silent
c.171C>A; p.A57A; 10:71279912-71279912	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2100C>T; p.F700F; 10:71293858-71293858	skin	malignant_melanoma	Substitution - coding silent
c.1905T>A; p.F635L; 10:71293537-71293537	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1787G>A; p.G596E; 10:71293419-71293419	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.612C>T; p.L204L; 10:71286748-71286748	breast	carcinoma	Substitution - coding silent
c.1879G>A; p.E627K; 10:71293511-71293511	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1594C>T; p.Q532*; 10:71291731-71291731	skin	malignant_melanoma	Substitution - Nonsense
c.2184G>A; p.L728L; 10:71295819-71295819	skin	malignant_melanoma	Substitution - coding silent
c.1122G>A; p.A374A; 10:71290937-71290937	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1731C>A; p.F577L; 10:71292513-71292513	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2449delG; p.E818fs*53; 10:71296701-71296701	skin	malignant_melanoma	Deletion - Frameshift
c.2731G>A; p.E911K; 10:71299170-71299170	skin; neck	malignant_melanoma	Substitution - Missense
c.871C>T; p.Q291*; 10:71287735-71287735	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1505T>A; p.L502Q; 10:71291642-71291642	liver	carcinoma	Substitution - Missense
c.2785G>A; p.E929K; 10:71299224-71299224	skin	malignant_melanoma	Substitution - Missense
c.1505T>A; p.L502Q; 10:71291642-71291642	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.372G>A; p.E124E; 10:71284787-71284787	skin	malignant_melanoma	Substitution - coding silent
c.2065C>A; p.R689S; 10:71293823-71293823	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.965G>T; p.R322L; 10:71288631-71288631	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2336T>G; p.F779C; 10:71296588-71296588	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.465C>T; p.F155F; 10:71285342-71285342	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.360C>A; p.L120L; 10:71284775-71284775	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1739T>A; p.M580K; 10:71292521-71292521	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2160G>A; p.T720T; 10:71293918-71293918	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1914G>C; p.K638N; 10:71293546-71293546	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2160G>A; p.T720T; 10:71293918-71293918	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related	Substitution - coding silent
c.166G>A; p.D56N; 10:71279907-71279907	skin	malignant_melanoma	Substitution - Missense
c.1210C>G; p.R404G; 10:71291025-71291025	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.812G>A; p.R271Q; 10:71287676-71287676	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.237C>A; p.F79L; 10:71279978-71279978	skin	malignant_melanoma	Substitution - Missense
c.1633G>A; p.V545I; 10:71291770-71291770	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2739G>A; p.L913L; 10:71299178-71299178	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1210C>G; p.R404G; 10:71291025-71291025	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1633G>A; p.V545I; 10:71291770-71291770	stomach	adenocarcinoma	Substitution - Missense
c.782G>T; p.R261L; 10:71287646-71287646	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1563C>T; p.F521F; 10:71291700-71291700	skin	malignant_melanoma	Substitution - coding silent
c.1563C>T; p.F521F; 10:71291700-71291700	skin	malignant_melanoma	Substitution - coding silent
c.1563C>T; p.F521F; 10:71291700-71291700	skin	malignant_melanoma	Substitution - coding silent
c.1638C>T; p.S546S; 10:71291775-71291775	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2429T>A; p.I810N; 10:71296681-71296681	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1267C>T; p.P423S; 10:71291082-71291082	skin	malignant_melanoma	Substitution - Missense
c.424C>T; p.R142C; 10:71284839-71284839	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1137G>A; p.G379G; 10:71290952-71290952	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.531G>A; p.P177P; 10:71285408-71285408	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1892G>A; p.R631H; 10:71293524-71293524	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1324C>T; p.P442S; 10:71291461-71291461	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2628G>A; p.R876R; 10:71298046-71298046	skin	malignant_melanoma	Substitution - coding silent
c.2212T>G; p.L738V; 10:71295847-71295847	skin	malignant_melanoma	Substitution - Missense
c.288C>T; p.G96G; 10:71280029-71280029	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.288C>T; p.G96G; 10:71280029-71280029	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.2626C>T; p.R876W; 10:71298044-71298044	large_intestine; rectum	NS	Substitution - Missense
c.2790G>A; p.M930I; 10:71299229-71299229	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.238A>G; p.K80E; 10:71279979-71279979	skin	malignant_melanoma	Substitution - Missense
c.2790G>A; p.M930I; 10:71299229-71299229	skin	malignant_melanoma	Substitution - Missense
c.917C>T; p.T306M; 10:71288583-71288583	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1827C>G; p.P609P; 10:71293459-71293459	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1827C>G; p.P609P; 10:71293459-71293459	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.2772G>A; p.A924A; 10:71299211-71299211	liver	carcinoma	Substitution - coding silent
c.1733A>G; p.Y578C; 10:71292515-71292515	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2460G>C; p.Q820H; 10:71296712-71296712	thyroid	other; neoplasm	Substitution - Missense
c.1572G>A; p.L524L; 10:71291709-71291709	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2586C>T; p.I862I; 10:71298004-71298004	skin	malignant_melanoma	Substitution - coding silent
c.2020C>T; p.L674L; 10:71293778-71293778	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2263C>T; p.R755C; 10:71295898-71295898	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related	Substitution - Missense
c.1051G>T; p.G351W; 10:71288717-71288717	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2263C>T; p.R755C; 10:71295898-71295898	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1653C>T; p.C551C; 10:71291790-71291790	skin	malignant_melanoma	Substitution - coding silent
c.776C>T; p.S259F; 10:71287640-71287640	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.873G>A; p.Q291Q; 10:71287737-71287737	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.965G>A; p.R322H; 10:71288631-71288631	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2646G>A; p.M882I; 10:71298064-71298064	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.619G>A; p.D207N; 10:71286755-71286755	skin	malignant_melanoma	Substitution - Missense
c.721G>A; p.V241I; 10:71286857-71286857	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1001G>A; p.G334E; 10:71288667-71288667	skin	malignant_melanoma	Substitution - Missense
c.526C>T; p.P176S; 10:71285403-71285403	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1124C>T; p.A375V; 10:71290939-71290939	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2221G>T; p.E741*; 10:71295856-71295856	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1047A>C; p.T349T; 10:71288713-71288713	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1828A>T; p.T610S; 10:71293460-71293460	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.301A>T; p.T101S; 10:71280042-71280042	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1741T>C; p.Y581H; 10:71292523-71292523	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1804A>G; p.S602G; 10:71293436-71293436	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.764G>A; p.W255*; 10:71287628-71287628	skin; trunk	malignant_melanoma	Substitution - Nonsense
c.2399G>T; p.S800I; 10:71296651-71296651	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.365G>T; p.G122V; 10:71284780-71284780	prostate	carcinoma	Substitution - Missense
c.2404G>A; p.A802T; 10:71296656-71296656	skin; acral	malignant_melanoma	Substitution - Missense
c.1574G>A; p.R525H; 10:71291711-71291711	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1259G>A; p.G420D; 10:71291074-71291074	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1774C>T; p.P592S; 10:71293406-71293406	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1258G>C; p.G420R; 10:71291073-71291073	breast	carcinoma	Substitution - Missense
c.2474A>T; p.H825L; 10:71296726-71296726	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.860G>A; p.G287D; 10:71287724-71287724	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1540G>A; p.D514N; 10:71291677-71291677	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.358C>A; p.L120I; 10:71284773-71284773	breast	carcinoma	Substitution - Missense
c.1436G>A; p.S479N; 10:71291573-71291573	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2553G>T; p.L851L; 10:71297971-71297971	skin	malignant_melanoma	Substitution - coding silent
c.811C>T; p.R271W; 10:71287675-71287675	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.879C>T; p.T293T; 10:71287743-71287743	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.337T>A; p.S113T; 10:71284752-71284752	parathyroid	adenoma	Substitution - Missense
c.414C>T; p.T138T; 10:71284829-71284829	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.169G>A; p.A57T; 10:71279910-71279910	breast	carcinoma	Substitution - Missense
c.414C>T; p.T138T; 10:71284829-71284829	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.169G>A; p.A57T; 10:71279910-71279910	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.860G>T; p.G287V; 10:71287724-71287724	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1510G>T; p.G504W; 10:71291647-71291647	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1156G>A; p.V386M; 10:71290971-71290971	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2300G>A; p.R767K; 10:71295935-71295935	thyroid	carcinoma	Substitution - Missense
c.1199G>A; p.R400H; 10:71291014-71291014	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.1573C>T; p.R525C; 10:71291710-71291710	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.733+1G>T; p.?; 10:71286870-71286870	breast	carcinoma	Unknown
c.428G>T; p.R143L; 10:71284843-71284843	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.647G>A; p.R216H; 10:71286783-71286783	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.86A>C; p.D29A; 10:71279827-71279827	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1270G>A; p.V424I; 10:71291085-71291085	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.647G>A; p.R216H; 10:71286783-71286783	pancreas	carcinoma	Substitution - Missense
c.408G>A; p.A136A; 10:71284823-71284823	thyroid	other; neoplasm	Substitution - coding silent
c.1676C>A; p.P559H; 10:71291813-71291813	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.408G>A; p.A136A; 10:71284823-71284823	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2176G>A; p.E726K; 10:71295811-71295811	skin	malignant_melanoma	Substitution - Missense
c.92G>A; p.G31D; 10:71279833-71279833	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2064C>T; p.S688S; 10:71293822-71293822	skin; trunk	malignant_melanoma; nodular	Substitution - coding silent
c.1258G>A; p.G420S; 10:71291073-71291073	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.2487A>G; p.A829A; 10:71296739-71296739	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2217G>T; p.V739V; 10:71295852-71295852	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.862C>T; p.Q288*; 10:71287726-71287726	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.637C>T; p.R213C; 10:71286773-71286773	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1340C>A; p.A447D; 10:71291477-71291477	pancreas	carcinoma	Substitution - Missense
c.1340C>A; p.A447D; 10:71291477-71291477	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.247G>T; p.G83C; 10:71279988-71279988	prostate	adenoma	Substitution - Missense
c.319G>T; p.E107*; 10:71284734-71284734	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2271C>T; p.S757S; 10:71295906-71295906	skin	malignant_melanoma	Substitution - coding silent
c.319G>T; p.E107*; 10:71284734-71284734	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Nonsense
c.506A>T; p.E169V; 10:71285383-71285383	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1612C>T; p.P538S; 10:71291749-71291749	stomach	adenocarcinoma	Substitution - Missense
c.1256G>C; p.G419A; 10:71291071-71291071	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.924G>A; p.W308*; 10:71288590-71288590	skin	malignant_melanoma	Substitution - Nonsense
c.2587C>T; p.R863C; 10:71298005-71298005	skin	malignant_melanoma	Substitution - Missense
c.1674C>G; p.I558M; 10:71291811-71291811	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2414A>G; p.E805G; 10:71296666-71296666	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1632C>A; p.S544R; 10:71291769-71291769	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2331C>T; p.I777I; 10:71296583-71296583	skin	malignant_melanoma	Substitution - coding silent
c.1347C>T; p.A449A; 10:71291484-71291484	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.856G>A; p.E286K; 10:71287720-71287720	prostate	carcinoma	Substitution - Missense
c.700C>T; p.R234C; 10:71286836-71286836	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2451G>C; p.G817G; 10:71296703-71296703	skin	malignant_melanoma	Substitution - coding silent
c.1269C>A; p.P423P; 10:71291084-71291084	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1022C>T; p.T341M; 10:71288688-71288688	pancreas	carcinoma	Substitution - Missense
c.2405C>G; p.A802G; 10:71296657-71296657	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2102C>T; p.A701V; 10:71293860-71293860	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1412C>T; p.S471F; 10:71291549-71291549	skin; hand	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1469C>T; p.T490M; 10:71291606-71291606	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.316C>T; p.R106C; 10:71284731-71284731	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.1181T>G; p.V394G; 10:71290996-71290996	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1469C>T; p.T490M; 10:71291606-71291606	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.671C>T; p.T224I; 10:71286807-71286807	skin	malignant_melanoma	Substitution - Missense
c.402C>T; p.S134S; 10:71284817-71284817	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.402C>T; p.S134S; 10:71284817-71284817	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1507C>T; p.L503L; 10:71291644-71291644	breast	carcinoma	Substitution - coding silent
c.1113A>G; p.S371S; 10:71290928-71290928	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1302G>A; p.P434P; 10:71291439-71291439	endometrium	carcinoma; serous_carcinoma	Substitution - coding silent
c.567G>T; p.K189N; 10:71286703-71286703	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.413C>T; p.T138I; 10:71284828-71284828	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.404C>T; p.S135F; 10:71284819-71284819	skin	malignant_melanoma	Substitution - Missense
c.2580G>C; p.L860L; 10:71297998-71297998	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2792G>A; p.G931D; 10:71299231-71299231	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1130A>G; p.Y377C; 10:71290945-71290945	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2365G>A; p.A789T; 10:71296617-71296617	skin; hand	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1189G>T; p.V397L; 10:71291004-71291004	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1549C>T; p.R517W; 10:71291686-71291686	central_nervous_system; brain	glioma; oligodendroglioma_Grade_III	Substitution - Missense
c.2671C>T; p.R891W; 10:71298089-71298089	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2671C>T; p.R891W; 10:71298089-71298089	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.861C>T; p.G287G; 10:71287725-71287725	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1432C>T; p.P478S; 10:71291569-71291569	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2808G>T; p.L936L; 10:71299247-71299247	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2063C>G; p.S688C; 10:71293821-71293821	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1526G>T; p.G509V; 10:71291663-71291663	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2659C>T; p.L887F; 10:71298077-71298077	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.2361G>A; p.Q787Q; 10:71296613-71296613	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.690C>T; p.I230I; 10:71286826-71286826	skin	malignant_melanoma	Substitution - coding silent
c.2479A>G; p.T827A; 10:71296731-71296731	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2708C>T; p.T903M; 10:71299147-71299147	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2708C>T; p.T903M; 10:71299147-71299147	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.642G>T; p.Q214H; 10:71286778-71286778	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.912G>A; p.A304A; 10:71288578-71288578	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.530C>T; p.P177L; 10:71285407-71285407	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.912G>A; p.A304A; 10:71288578-71288578	breast	carcinoma	Substitution - coding silent
c.1361G>A; p.G454E; 10:71291498-71291498	skin	malignant_melanoma	Substitution - Missense
c.1496G>A; p.G499E; 10:71291633-71291633	skin	malignant_melanoma	Substitution - Missense
c.1285G>A; p.A429T; 10:71291100-71291100	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1494T>C; p.D498D; 10:71291631-71291631	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1361G>A; p.G454E; 10:71291498-71291498	skin	malignant_melanoma	Substitution - Missense
c.715G>A; p.A239T; 10:71286851-71286851	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.1285G>A; p.A429T; 10:71291100-71291100	prostate	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]