Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

1793

Name

DOCK1

Synonymous

dedicator of cytokinesis 1;DOCK1;dedicator of cytokinesis 1

Definition

180 kDa protein downstream of CRK|DOwnstream of CrK|dedicator of cytokinesis protein 1

Position

10q26.13-q26.3

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

DOCK180(h) + ELMO2(h) <==> DOCK180(h):ELMO2(h) (binding)
DOCK180(h) + ELMO3(h) <==> DOCK180(h):ELMO3(h) (binding)
DOCK180(h) --> ELMO2(h) (binding)
DOCK1(h) --> DOCK180(h) (expression).
DOCK180(h) + Rac1(mo) <==> DOCK180(h):Rac1(mo) (binding)
DOCK1(h) --> DOCK180(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

1858Phosphoserine.Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr10

Promoter: 128582513 - 128584513Agilent_014791

chr10

Promoter: 128582513 - 128584513GSE27584

chr10

Promoter: 128582513 - 128584513Agilent_014791_44K