| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1793 |
Name | DOCK1 |
Synonym | DOCK180|ced5;dedicator of cytokinesis 1;DOCK1;dedicator of cytokinesis 1 |
Definition | 180 kDa protein downstream of CRK|DOwnstream of CrK|dedicator of cytokinesis protein 1 |
Position | 10q26.13-q26.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Bacterial invasion of epithelial cells;KEGG PATHWAY;hsa05100 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | Neurotrophic factor-mediated Trk receptor signaling;PID Curated;200128 |
Pathway | Shigellosis;KEGG PATHWAY;hsa05131 |
Pathway | Regulation of RAC1 activity;PID Curated;200165 |
Pathway | Paxillin-independent events mediated by a4b1 and a4b7;PID Curated;200178 |
Pathway | Signaling events mediated by focal adhesion kinase;PID Curated;200192 |
Pathway | Netrin-mediated signaling;PID Curated;200074 |
External Links | |
Links to Entrez Gene | 1793 |
Links to all GeneRIF Items | 1793 |
Links to iHOP | 1793 |
Sequence Information | |
Nucleotide Sequence | >1793 : length: 7315 TCCTGAGGTTGGGGATATGTGTGCTGGGCCTGGCCCAGGGTAGTACTGGGGTTGCGTGAG AAGGCAGGTCTGGAGCTGGTTGTATGCCTGGGCCCCGCAAGCTGGGCTTTCAGAATCCCT TTCAGTGGCCCGGGCCCACCCCCTGGACCCTGTTCCCTTTGTAACTGAGCTTTCGTCTTT GCTTTGGTTCCCTGGCCACCCTTCGGGATCCTGGCCTCCCCTTTCTGGGAGTGGTGCACG TTCTGCTGGGGGGAGGTGCATCCTGCCCTTGCTGCCTGCCTGGCACTCTGGGTTCCCCTC TGCACTTGTTTGCTGATCCATCTCCATTGATTCCCGAAGGTGTTTATTGAAGGTGACCTG GGTTGGGGGACATGGGGTTAACACACCCAGCTCCTGCTCTCCTGCAGCCCTCTCCCTGTG GGGAATGGGGAGCCGCAGGACAGCCCCTAAGCTGTCTAGTGCCTCTGGGGATTCCAGGAA GGCACTTCTTGGTTGGACATGTTGCTTGACAAGTGCAACCCAGGCAGGATTTCGGCTCCC ACGTGTCCCTTCAGCCCTGAGCCTTTGGCAGTGAACACACCTACCAACTATACATGGCAG TCCAAAGTGGCTTTTTATAACTATGATGCCAGAGGAGCGGATGAACTTTCTTTACAGATC GGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGA AAAAAGTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTT GAAGGAAAAGGGCAACATGAAACAGTCATCCCGGGTGACCTCCCCCTCATCCAGGAAGTC ACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGG GAGATGTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATT CTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGAACTGAAGAAGAAGGTCACAGCCAAA ATTGATTATGGAAACAGAATTCTAGATTTGGACCTGGTGGTTAGAGATGAAGATGGGAAT ATTTTGGATCCAGAATTAACTAGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCT AAACAAGTGGAGGAAAGGTTACAAGAGGAAAAATCTCAAAAGCAGAACATAGATATTAAC AGACAAGCCAAGTTTGCTGCAACCCCTTCTCTGGCCTTGTTTGTGAACCTCAAAAATGTG GTTTGTAAAATAGGAGAAGATGCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCC AAATTCATCAGTGAGAACTACCTGGTTCGCTGGTCCAGTTCAGGATTACCTAAAGACATA GACAGATTACATAATTTGCGAGCCGTGTTTACTGACCTCGGAAGCAAAGACCTGAAAAGG GAGAAAATCAGTTTTGTCTGTCAGATTGTTCGCGTGGGTCGCATGGAGCTGAGGGACAAC AACACCAGGAAACTGACCTCGGGGTTGCGGCGACCTTTTGGAGTGGCTGTGATGGATGTA ACAGATATAATAAATGGAAAAGTAGATGATGAAGATAAGCAGCATTTCATTCCCTTTCAG CCGCTCGCGTTGGACGACGCCATTCGACACAAGCCGCTGAACATGTCATCCCGTTTTTCA CCCAGGGTGGCAGGGGAGAATGACTTCCTTCAGACTGTTATAAACAAAGTCATCGCTGCC AAAGAAGTCAACCACAAGGGGCAGGGTTTGTGGGTAACATTGAAATTACTTCCTGGAGAT ATCCATCAGATCCGAAAAGAGTTTCCGCATTTAGTGGACAGGACCACAGCTGTGGCTCGA AAAACAGGGTTTCCGGAGATAATCATGCCTGGTGATGTTCGAAATGATATCTATGTAACA TTAGTTCAAGGAGATTTTGATAAAGGAAGCAAAACAACAGCGAAGAACGTGGAGGTCACG GTGTCTGTGTACGATGAGGATGGGAAACGATTAGAGCATGTGATTTTCCCGGGTGCTGGT GATGAAGCGATTTCAGAGTACAAATCTGTGATTTACTACCAAGTAAAGCAGCCACGCTGG TTTGAGACTGTTAAGGTGGCCATTCCCATCGAGGACGTTAACCGCAGTCACCTTCGGTTT ACCTTCCGCCACAGGTCATCACAGGACTCTAAGGATAAATCTGAGAAAATATTTGCACTA GCATTTGTCAAGCTGATGAGATACGATGGTACCACCCTGCGAGACGGAGAGCACGATCTT ATCGTCTATAAGGCCGAAGCAAAGAAGCTGGAAGATGCTGCCACGTACTTGAGTCTGCCC TCCACGAAGGCAGAGTTGGAAGAAAAGGGCCACTCGGCCACCGGCAAGAGCATGCAGAGC CTTGGGAGCTGCACCATTAGCAAGGACTCCTTCCAGATCTCCACGCTCGTGTGCTCCACC AAACTGACTCAGAACGTGGACCTTCTGGGGCTCTTGAAATGGCGCTCCAACACCAGCCTG CTGCAGCAGAACTTGAGGCAGCTGATGAAAGTCGATGGTGGTGAAGTAGTGAAGTTTCTT CAGGACACGTTGGATGCCCTCTTCAACATCATGATGGAGAACTCAGAGAGTGAGACTTTT GACACGTTAGTCTTTGATGCTCTGGTATTTATCATTGGACTGATTGCTGATAGAAAATTT CAGCATTTTAATCCTGTTTTGGAAACTTACATTAAGAAACACTTTAGTGCAACGTTAGCC TACACGAAGTTGACAAAAGTGTTGAAGAACTACGTGGACGGTGCTGAGAAGCCGGGAGTA AATGAGCAGCTGTACAAAGCCATGAAAGCGCTAGAATCCATCTTCAAGTTCATCGTGCGC TCCAGGATCCTGTTCAATCAACTGTATGAAAACAAGGGAGAGGCTGACTTCGTGGAATCT TTGCTGCAGCTCTTCAGGTCCATCAATGACATGATGAGCAGCATGTCAGACCAGACCGTC CGGGTGAAGGGGGCAGCACTGAAATACTTACCAACGATCGTCAACGATGTGAAATTGGTG TTTGATCCCAAAGAGCTCAGCAAAATGTTTACTGAATTCATCCTCAATGTTCCCATGGGC TTGCTGACCATCCAGAAACTCTACTGCTTGATCGAAATCGTCCACAGTGACCTCTTCACA CAGCATGACTGCAGAGAGATCCTGCTTCCCATGATGACCGATCAGCTCAAGTACCATCTG GAGAGACAGGAGGACCTGGAGGCCTGCTGTCAGCTGCTCAGCCACATCCTGGAGGTGCTG TACAGGAAGGACGTGGGGCCAACCCAGAGGCACGTCCAGATTATCATGGAGAAACTTCTC CGGACCGTGAACCGAACCGTCATTTCCATGGGACGAGATTCTGAACTCATTGGAAACTTC GTGGCTTGCATGACAGCTATTTTACGACAAATGGAAGATTACCATTATGCCCACTTGATC AAGACTTTTGGGAAAATGAGGACTGATGTGGTAGATTTCCTAATGGAAACATTCATCATG TTTAAGAACCTCATTGGAAAGAACGTTTACCCCTTCGACTGGGTGATCATGAACATGGTG CAAAATAAAGTCTTCCTGCGAGCAATTAATCAGTATGCAGATATGCTGAACAAAAAATTT CTGGATCAAGCCAACTTTGAGCTACAGCTGTGGAACAACTACTTTCACCTGGCTGTTGCT TTCCTTACTCAAGAGTCCCTGCAACTGGAGAATTTTTCAAGTGCCAAGAGAGCCAAAATC CTTAACAAGTACGGAGATATGAGGAGACAGATTGGCTTTGAAATCAGAGACATGTGGTAC AACCTTGGTCAACACAAGATAAAGTTCATTCCAGAAATGGTGGGCCCAATATTAGAAATG ACATTAATTCCCGAGACGGAGCTGCGCAAAGCCACCATCCCCATCTTCTTTGATATGATG CAGTGTGAATTCCATTCGACCCGAAGCTTCCAAATGTTTGAAAATGAGATCATCACCAAG CTGGATCATGAAGTCGAAGGAGGCAGAGGAGACGAACAGTACAAAGTGTTATTTGATAAA ATCCTTCTGGAACACTGCAGGAAGCACAAATACCTCGCCAAAACAGGAGAAACTTTTGTA AAACTCGTTGTGCGCTTAATGGAAAGGCTTTTGGATTATAGAACCATCATGCACGACGAG AACAAAGAAAACCGCATGAGCTGCACCGTCAATGTGCTGAATTTCTACAAAGAAATTGAA AGAGAAGAAATGTATATAAGGTATTTGTACAAGCTCTGTGACCTGCACAAGGAGTGTGAT AACTACACCGAAGCGGCTTACACCTTGCTTCTCCATGCAAAGCTTCTTAAGTGGTCGGAG GATGTGTGTGTGGCCCACCTCACCCAGCGGGACGGGTACCAGGCCACCACGCAGGGACAG CTGAAGGAGCAGCTCTACCAGGAAATCATCCACTACTTCGACAAAGGCAAGATGTGGGAG GAGGCCATTGCCTTGGGCAAGGAGCTAGCCGAGCAGTATGAGAACGAAATGTTTGATTAT GAGCAACTCAGCGAATTGCTGAAAAAACAGGCTCAGTTTTATGAAAACATCGTCAAAGTG ATCAGGCCCAAGCCTGACTATTTTGCTGTTGGCTACTACGGACAAGGGTTCCCCACATTC CTGCGGGGAAAAGTTTTCATTTACCGAGGGAAAGAGTATGAGCGCCGGGAAGATTTTGAG GCTCGGCTCTTAACTCAGTTTCCAAACGCCGAGAAAATGAAGACAACATCTCCACCAGGC GACGATATTAAAAACTCTCCTGGCCAGTATATTCAGTGCTTCACAGTGAAGCCCAAACTC GATCTGCCTCCTAAGTTTCACAGGCCAGTGTCAGAGCAGATTGTAAGTTTTTACAGGGTG AACGAGGTCCAGCGATTTGAATATTCTCGGCCAATCCGGAAGGGAGAGAAAAACCCAGAC AATGAATTTGCGAATATGTGGATCGAGAGAACCATATATACAACTGCATATAAATTACCT GGAATTTTAAGGTGGTTTGAGGTCAAGTCTGTTTTCATGGTGGAAATCAGCCCCCTGGAG AATGCCATTGAGACCATGCAGCTGACGAACGACAAGATCAACAGCATGGTGCAGCAGCAC CTGGATGACCCCAGCCTGCCCATCAACCCGCTCTCCATGCTCCTGAACGGCATCGTGGAC CCAGCTGTCATGGGGGGCTTCGCAAACTACGAAAAGGCCTTCTTTACAGACCGGTACCTG CAGGAGCACCCTGAGGCCCATGAAAAGATCGAGAAGCTCAAGGACCTGATTGCTTGGCAG ATTCCTTTTCTGGCCGAAGGGATCAGAATCCATGGAGACAAAGTCACGGAGGCACTGAGG CCGTTCCACGAGAGGATGGAGGCCTGTTTCAAACAGCTGAAGGAAAAGGTGGAGAAAGAG TACGGCGTCCGAATCATGCCCTCAAGTCTGGATGATAGAAGAGGCAGCCGCCCCCGGTCC ATGGTGCGGTCCTTCACGATGCCTTCCTCATCCCGCCCTCTGTCTGTGGCCTCTGTCTCT TCCCTCTCATCGGACAGCACCCCTTCCAGACCAGGCTCCGACGGGTTTGCCCTGGAGCCT CTCCTGCCAAAGAAAATGCACTCCAGGTCCCAGGACAAGCTGGACAAGGATGACCTGGAG AAGGAGAAGAAGGACAAGAAGAAGGAAAAAAGGAACAGCAAACATCAAGAGATATTTGAG AAAGAATTTAAACCCACCGACATTTCCCTGCAGCAGTCTGAGGCTGTGATCCTTTCGGAA ACGATAAGTCCCCTGCGGCCCCAGAGACCGAAGAGCCAGGTGATGAACGTCATTGGAAGC GAAAGGCGCTTCTCGGTGTCCCCCTCGTCACCGTCCTCCCAGCAAACACCCCCTCCAGTT ACACCAAGGGCCAAGCTCAGCTTCAGCATGCAGTCGAGCTTGGAGCTGAACGGCATGACG GGGGCGGACGTGGCCGATGTCCCACCCCCTCTGCCTCTCAAAGGCAGCGTGGCAGATTAC GGGAATTTGATGGAAAACCAGGACTTGCTGGGCTCGCCAACACCTCCACCTCCCCCTCCA CACCAGAGGCATCTGCCACCTCCACTGCCCAGCAAAACTCCGCCTCCTCCCCCTCCAAAG ACAACTCGCAAGCAGGCATCGGTGGACTCCGGGATCGTGCAGTGACGTCGCAAGCCTCTC TGGAAAGAGTGTGCTGCCCCTCCCCATCTCCATGCCCTCTCCTTCTGTGTCCCCTGAGTC TGCTGTTTACCTCATTGGGCCTGTGATGTTAACATTTCGTGCGACTGCTTTTTCTTCAAA GGAGTTCAGTTCTCACCATGGAGTGAGTGGCCTTTAGCGTCATGGAGCAAGGTGGGTCTG GGAGGTAGATATGGGTCCGGGATGTGCTATCGTAGTTATCAGAGTTGGGGGCCTCTGAGT GTGTCTGGCTCTGAGAGAGTCTGAGTCTTGCCCAAACATTCTTTCTTTTTGTGCCAAATG ACTTGCATTTGCAAAGAGCTCAATTGCTCTGAGCTCAGCCAAGTAGGAGAGGCTAGGCCA TCACTCTTAGGAAGCTGTGTAGTGATGATGTATAAGAATCCTCCTCACTGTCATGGGATG TTGTATCCAGCCCCTCCTTGTTCCAGCCGGTGGTGTGACTTCGTTGGTTGAGGTGTGTCT CCAACCTACATCAGACCATGAAGTTCAACCCCTCCAGGGAAGCTCCTGATTTCCCCTGCA TAATTGAAAATAGGATATTTCTCAGCTATTGAACAGTTACTAATTTATGGGGTGGAAACA GCATTAAGAATACTGAATCAAATGGAAAAACAAATGAATACAGGAAGATAAGTGTTCGTT CTTTTCTGAAAAAGAGTATGTGTACCACAAGAGCTGGTTTTAATTGGGTGAATTGTTTTT GTCCTCATTCTGTACAGAAATTTGTATATATGATGGTTCTTAGAACTTGTTTTAATTTTT GTGGTCCTTCCGTTTATTATAATAGGCGTCCACCAATGATTATCCATATGTGTTCTTAAT TTTTAACTGCTGGAAGTGTTAAAACACACACACACACACACACACATTTTTTTTTTGAGA ACTCCAAAGTCCTGAAAATTTTGGTGGACAATGATTTTTAAAAAACTAACTTTGTATAAC CTAATATTTGTATTCTCTCATCTATATTTTTTTATTCACTATAATCATGATACTCTTCTA ATAGACTTAAAAGTTAATCATTGACAACGAAAAATAAAATGTTATTTTAAAAGAC |
Protein Sequence | >1793 : length: 1925 MEKESFPMWGCRVRYAEPEALLPRNPHLSEPVMRAPSCAAAIQPGSQASPPWNHSFYNYD ARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPASYIHLKEAIVEGKGQHETV IPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDE LKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQE EKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLV RWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLTSGL RRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPLALDDAIRHKPLNMSSRFSPRVAGENDF LQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIM PGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKS VIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYD GTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKD SFQISTLVCSTKLTQNVDLLGLLKWRSNTSLLQQNLRQLMKVDGGEVVKFLQDTLDALFN IMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLK NYVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSIN DMMSSMSDQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYC LIEIVHSDLFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRKDVGPTQ RHVQIIMEKLLRTVNRTVISMGRDSELIGNFVACMTAILRQMEDYHYAHLIKTFGKMRTD VVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFLDQANFELQ LWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKF IPEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTRSFQMFENEIITKLDHEVEGGR GDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKENRMSCT VNVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCVAHLTQ RDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYENEMFDYEQLSELLKK QAQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQFPN AEKMKTTSPPGDDIKNSPGQYIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYS RPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLT NDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEK IEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGVRIMPSS LDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTPSRPGSDGFALEPLLPKKMHSR SQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQR PKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPP PLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPPKTTRKQASVD SGIVQ |