Entrez Gene

Basic Information
Gene ID	1793
Name	DOCK1
Synonymous	dedicator of cytokinesis 1;DOCK1;dedicator of cytokinesis 1
Definition	180 kDa protein downstream of CRK\|DOwnstream of CrK\|dedicator of cytokinesis protein 1
Position	10q26.13-q26.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.2525T>C; p.I842T; 10:127110319-127110319	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.844T>C; p.F282L; 10:126999430-126999430	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2408C>T; p.T803M; 10:127106256-127106256	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3427G>C; p.E1143Q; 10:127373838-127373838	prostate	carcinoma	Substitution - Missense
c.2987T>C; p.F996S; 10:127339011-127339011	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4683C>T; p.I1561I; 10:127419719-127419719	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2683G>C; p.D895H; 10:127125596-127125596	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.4118G>A; p.R1373Q; 10:127409095-127409095	liver	carcinoma	Substitution - Missense
c.642A>G; p.Q214Q; 10:126998124-126998124	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.3162-2A>G; p.?; 10:127354667-127354667	lung	carcinoma; adenocarcinoma	Unknown
c.1604A>T; p.K535M; 10:127031692-127031692	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.4705G>T; p.A1569S; 10:127419741-127419741	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3123G>A; p.E1041E; 10:127343708-127343708	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.5279C>T; p.S1760L; 10:127444208-127444208	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1618delG; p.D540fs*29; 10:127031706-127031706	autonomic_ganglia	neuroblastoma	Deletion - Frameshift
c.5393T>A; p.V1798D; 10:127447436-127447436	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1772G>A; p.S591N; 10:127032243-127032243	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.4930C>T; p.P1644S; 10:127433361-127433361	skin	malignant_melanoma	Substitution - Missense
c.4816G>A; p.E1606K; 10:127425976-127425976	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3351G>A; p.S1117S; 10:127362194-127362194	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.3351G>A; p.S1117S; 10:127362194-127362194	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4928G>A; p.R1643H; 10:127433359-127433359	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3284C>T; p.P1095L; 10:127362127-127362127	skin	malignant_melanoma	Substitution - Missense
c.3284C>T; p.P1095L; 10:127362127-127362127	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4993G>T; p.D1665Y; 10:127433424-127433424	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1232G>A; p.R411Q; 10:127018803-127018803	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.710G>T; p.G237V; 10:126998192-126998192	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3220+3G>A; p.?; 10:127354730-127354730	liver	carcinoma	Unknown
c.4840G>A; p.V1614I; 10:127426000-127426000	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3220+3G>A; p.?; 10:127354730-127354730	liver	carcinoma	Unknown
c.2919G>A; p.K973K; 10:127257367-127257367	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.672C>T; p.A224A; 10:126998154-126998154	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2223G>T; p.A741A; 10:127052765-127052765	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1845G>T; p.Q615H; 10:127032316-127032316	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5348C>T; p.S1783L; 10:127444277-127444277	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3114G>T; p.L1038L; 10:127343699-127343699	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2695A>T; p.T899S; 10:127127675-127127675	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1799A>G; p.D600G; 10:127032270-127032270	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.910G>A; p.V304M; 10:127000232-127000232	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4357G>C; p.E1453Q; 10:127410916-127410916	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4901G>A; p.R1634Q; 10:127433332-127433332	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.5593C>T; p.Q1865*; 10:127451422-127451422	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2223G>A; p.A741A; 10:127052765-127052765	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.248C>T; p.P83L; 10:126987541-126987541	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.210G>A; p.A70A; 10:126981956-126981956	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2210A>C; p.K737T; 10:127052752-127052752	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.362T>C; p.M121T; 10:126990492-126990492	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4697A>G; p.D1566G; 10:127419733-127419733	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.4883G>A; p.R1628H; 10:127433314-127433314	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2163C>A; p.N721K; 10:127052705-127052705	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4883G>T; p.R1628L; 10:127433314-127433314	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1648G>A; p.D550N; 10:127031736-127031736	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4762G>A; p.E1588K; 10:127425922-127425922	skin	malignant_melanoma	Substitution - Missense
c.3849C>A; p.Y1283*; 10:127384894-127384894	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2532C>T; p.I844I; 10:127110326-127110326	breast	carcinoma	Substitution - coding silent
c.1302A>T; p.Q434H; 10:127023237-127023237	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3262A>T; p.I1088L; 10:127362105-127362105	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3463G>A; p.E1155K; 10:127374065-127374065	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5322G>A; p.R1774R; 10:127444251-127444251	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5160C>T; p.S1720S; 10:127439189-127439189	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.181C>T; p.P61S; 10:126981927-126981927	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.935A>G; p.N312S; 10:127000257-127000257	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3996C>T; p.I1332I; 10:127404366-127404366	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.4979C>T; p.S1660F; 10:127433410-127433410	skin	malignant_melanoma	Substitution - Missense
c.2892C>T; p.F964F; 10:127257340-127257340	skin	malignant_melanoma	Substitution - coding silent
c.373C>T; p.L125F; 10:126990503-126990503	skin	malignant_melanoma	Substitution - Missense
c.4143C>T; p.A1381A; 10:127409120-127409120	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.493G>T; p.V165L; 10:126996767-126996767	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5292C>T; p.S1764S; 10:127444221-127444221	skin	malignant_melanoma	Substitution - coding silent
c.1362G>T; p.V454V; 10:127023297-127023297	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3293A>G; p.E1098G; 10:127362136-127362136	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3293A>G; p.E1098G; 10:127362136-127362136	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4851+8_4851+9insGTA; p.?; 10:127426019-127426020	oesophagus; lower_third	carcinoma; adenocarcinoma	Unknown
c.5316A>G; p.T1772T; 10:127444245-127444245	breast	carcinoma	Substitution - coding silent
c.4262T>G; p.V1421G; 10:127409373-127409373	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.856G>A; p.G286R; 10:127000178-127000178	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1061T>G; p.V354G; 10:127012297-127012297	breast	carcinoma	Substitution - Missense
c.2812A>G; p.I938V; 10:127248035-127248035	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3723T>G; p.L1241L; 10:127381347-127381347	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4233C>T; p.L1411L; 10:127409344-127409344	prostate	carcinoma	Substitution - coding silent
c.4989C>A; p.G1663G; 10:127433420-127433420	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2689-1G>T; p.?; 10:127127668-127127668	lung; right_lower_lobe	carcinoma; adenocarcinoma	Unknown
c.1666-1G>A; p.?; 10:127032136-127032136	central_nervous_system; brain	glioma; oligodendroglioma_Grade_III	Unknown
c.3298C>T; p.R1100C; 10:127362141-127362141	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1668C>T; p.A556A; 10:127032139-127032139	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.5377G>A; p.A1793T; 10:127447420-127447420	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5377G>A; p.A1793T; 10:127447420-127447420	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2689-30_2694del36; p.?; 10:127127639-127127674	ovary	carcinoma; serous_carcinoma	Unknown
c.5377G>A; p.A1793T; 10:127447420-127447420	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.5377G>A; p.A1793T; 10:127447420-127447420	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.5334C>T; p.S1778S; 10:127444263-127444263	ovary	other; neoplasm	Substitution - coding silent
c.2252G>A; p.R751H; 10:127052794-127052794	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.193A>G; p.I65V; 10:126981939-126981939	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.562C>T; p.H188Y; 10:126996836-126996836	pancreas	carcinoma	Substitution - Missense
c.386G>A; p.R129Q; 10:126990516-126990516	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1353G>A; p.T451T; 10:127023288-127023288	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3766G>A; p.A1256T; 10:127384811-127384811	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4006C>G; p.P1336A; 10:127404376-127404376	breast	carcinoma	Substitution - Missense
c.5209C>T; p.R1737W; 10:127444138-127444138	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.917G>A; p.R306H; 10:127000239-127000239	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5209C>T; p.R1737W; 10:127444138-127444138	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.470A>T; p.N157I; 10:126990600-126990600	prostate	carcinoma	Substitution - Missense
c.57C>T; p.N19N; 10:126970712-126970712	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.917G>A; p.R306H; 10:127000239-127000239	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3848A>T; p.Y1283F; 10:127384893-127384893	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5428G>T; p.D1810Y; 10:127447471-127447471	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.2747G>A; p.R916Q; 10:127127727-127127727	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1927G>A; p.D643N; 10:127037796-127037796	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4943C>T; p.A1648V; 10:127433374-127433374	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4140C>T; p.N1380N; 10:127409117-127409117	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1403C>T; p.P468L; 10:127024698-127024698	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1446T>G; p.I482M; 10:127024741-127024741	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4325C>T; p.P1442L; 10:127410884-127410884	skin	malignant_melanoma	Substitution - Missense
c.959G>T; p.G320V; 10:127000281-127000281	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4629+4C>T; p.?; 10:127418545-127418545	pancreas	carcinoma	Unknown
c.1603A>G; p.K535E; 10:127031691-127031691	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4884delC; p.R1630fs*98; 10:127433315-127433315	thyroid	carcinoma; anaplastic_carcinoma	Deletion - Frameshift
c.1603A>G; p.K535E; 10:127031691-127031691	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4928G>T; p.R1643L; 10:127433359-127433359	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2087C>T; p.P696L; 10:127043113-127043113	skin	malignant_melanoma	Substitution - Missense
c.1503C>T; p.I501I; 10:127026366-127026366	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3616T>A; p.F1206I; 10:127380085-127380085	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3240C>T; p.F1080F; 10:127362083-127362083	skin	malignant_melanoma	Substitution - coding silent
c.2304C>T; p.F768F; 10:127061698-127061698	breast	carcinoma	Substitution - coding silent
c.5509C>A; p.P1837T; 10:127451338-127451338	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3532A>T; p.M1178L; 10:127374134-127374134	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1515C>T; p.N505N; 10:127026378-127026378	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.5042C>T; p.S1681F; 10:127439071-127439071	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2252G>T; p.R751L; 10:127052794-127052794	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3525G>A; p.V1175V; 10:127374127-127374127	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2739C>T; p.T913T; 10:127127719-127127719	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.79G>A; p.E27K; 10:126970734-126970734	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2173G>A; p.G725S; 10:127052715-127052715	central_nervous_system; brain	glioma	Substitution - Missense
c.3601G>A; p.V1201I; 10:127374203-127374203	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1748C>T; p.S583L; 10:127032219-127032219	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.3601G>A; p.V1201I; 10:127374203-127374203	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.5425G>A; p.A1809T; 10:127447468-127447468	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2337C>T; p.I779I; 10:127061731-127061731	skin	malignant_melanoma	Substitution - coding silent
c.1306G>T; p.D436Y; 10:127023241-127023241	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.514A>T; p.N172Y; 10:126996788-126996788	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1948T>A; p.F650I; 10:127042625-127042625	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.3209G>T; p.W1070L; 10:127354716-127354716	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2785-10T>C; p.?; 10:127247998-127247998	liver	carcinoma	Unknown
c.5043C>T; p.S1681S; 10:127439072-127439072	skin	malignant_melanoma	Substitution - coding silent
c.3781C>T; p.R1261W; 10:127384826-127384826	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.790T>C; p.S264P; 10:126999376-126999376	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3602T>C; p.V1201A; 10:127374204-127374204	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3584A>C; p.N1195T; 10:127374186-127374186	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3602T>C; p.V1201A; 10:127374204-127374204	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.629A>G; p.D210G; 10:126998111-126998111	skin	malignant_melanoma	Substitution - Missense
c.4795G>A; p.A1599T; 10:127425955-127425955	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4900C>T; p.R1634W; 10:127433331-127433331	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4900C>T; p.R1634W; 10:127433331-127433331	pancreas	carcinoma	Substitution - Missense
c.1273C>T; p.R425*; 10:127023208-127023208	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2652C>T; p.L884L; 10:127125565-127125565	oesophagus	carcinoma	Substitution - coding silent
c.3749C>T; p.S1250L; 10:127384794-127384794	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.228G>T; p.G76G; 10:126987521-126987521	liver	carcinoma	Substitution - coding silent
c.3749C>T; p.S1250L; 10:127384794-127384794	prostate	carcinoma	Substitution - Missense
c.3749C>T; p.S1250L; 10:127384794-127384794	skin	malignant_melanoma	Substitution - Missense
c.2454C>A; p.S818R; 10:127110248-127110248	thyroid	other; neoplasm	Substitution - Missense
c.2490G>T; p.M830I; 10:127110284-127110284	liver	carcinoma	Substitution - Missense
c.2490G>T; p.M830I; 10:127110284-127110284	liver	carcinoma	Substitution - Missense
c.1390C>T; p.H464Y; 10:127024685-127024685	liver	carcinoma	Substitution - Missense
c.1390C>T; p.H464Y; 10:127024685-127024685	liver	carcinoma	Substitution - Missense
c.5067C>T; p.D1689D; 10:127439096-127439096	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1274G>T; p.R425L; 10:127023209-127023209	liver	carcinoma	Substitution - Missense
c.4364C>T; p.A1455V; 10:127410923-127410923	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.4927C>T; p.R1643C; 10:127433358-127433358	breast	carcinoma	Substitution - Missense
c.4100G>A; p.R1367Q; 10:127409077-127409077	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1333G>C; p.A445P; 10:127023268-127023268	oesophagus	carcinoma	Substitution - Missense
c.2807C>T; p.T936I; 10:127248030-127248030	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5433C>T; p.Y1811Y; 10:127447476-127447476	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.837A>G; p.R279R; 10:126999423-126999423	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2419G>A; p.D807N; 10:127106267-127106267	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2419G>A; p.D807N; 10:127106267-127106267	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4775C>T; p.P1592L; 10:127425935-127425935	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.898C>G; p.Q300E; 10:127000220-127000220	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2949C>T; p.F983F; 10:127257397-127257397	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2967C>T; p.N989N; 10:127257415-127257415	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3852C>T; p.F1284F; 10:127384897-127384897	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2873G>C; p.R958T; 10:127248096-127248096	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1404G>A; p.P468P; 10:127024699-127024699	ovary	other; neoplasm	Substitution - coding silent
c.3060G>A; p.Q1020Q; 10:127339084-127339084	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - coding silent
c.2740G>T; p.V914L; 10:127127720-127127720	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4684G>C; p.E1562Q; 10:127419720-127419720	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.1222G>A; p.A408T; 10:127018793-127018793	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5184C>T; p.I1728I; 10:127439213-127439213	skin	malignant_melanoma	Substitution - coding silent
c.4076A>G; p.Y1359C; 10:127409053-127409053	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2456A>C; p.K819T; 10:127110250-127110250	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.2118T>C; p.F706F; 10:127043144-127043144	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4581C>T; p.N1527N; 10:127418493-127418493	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5412C>G; p.L1804L; 10:127447455-127447455	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4141G>A; p.A1381T; 10:127409118-127409118	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4141G>A; p.A1381T; 10:127409118-127409118	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1501A>T; p.I501F; 10:127026364-127026364	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2905T>C; p.F969L; 10:127257353-127257353	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2566A>T; p.R856*; 10:127125479-127125479	kidney	other; neoplasm	Substitution - Nonsense
c.420T>G; p.D140E; 10:126990550-126990550	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2566A>T; p.R856*; 10:127125479-127125479	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.4217C>T; p.T1406I; 10:127409328-127409328	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1308T>C; p.D436D; 10:127023243-127023243	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.500G>T; p.R167I; 10:126996774-126996774	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1740G>C; p.K580N; 10:127032211-127032211	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.850-10A>G; p.?; 10:127000162-127000162	liver	carcinoma	Unknown
c.850-10A>G; p.?; 10:127000162-127000162	liver	carcinoma	Unknown
c.1606C>T; p.L536L; 10:127031694-127031694	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4057C>T; p.R1353W; 10:127404427-127404427	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1870A>G; p.K624E; 10:127037739-127037739	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2491_2492GG>TA; p.G831>?; 10:127110285-127110286	lung	carcinoma; adenocarcinoma	Complex
c.1863G>A; p.G621G; 10:127037732-127037732	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3240C>A; p.F1080L; 10:127362083-127362083	breast	carcinoma	Substitution - Missense
c.4442C>A; p.S1481Y; 10:127415228-127415228	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2028T>C; p.F676F; 10:127042705-127042705	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3664A>G; p.K1222E; 10:127381288-127381288	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1058+1G>C; p.?; 10:127008805-127008805	NS	NS	Unknown
c.900G>T; p.Q300H; 10:127000222-127000222	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4888C>G; p.R1630G; 10:127433319-127433319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3401A>T; p.H1134L; 10:127373812-127373812	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.149C>A; p.T50K; 10:126977966-126977966	pancreas	carcinoma	Substitution - Missense
c.1914G>A; p.Q638Q; 10:127037783-127037783	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.527C>A; p.P176Q; 10:126996801-126996801	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1427C>T; p.S476L; 10:127024722-127024722	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1842T>A; p.T614T; 10:127032313-127032313	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.2760C>A; p.S920S; 10:127127740-127127740	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1366_1368delGAT; p.D456delD; 10:127023301-127023303	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.4234G>A; p.D1412N; 10:127409345-127409345	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5422G>A; p.V1808M; 10:127447465-127447465	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5422G>A; p.V1808M; 10:127447465-127447465	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3189C>T; p.G1063G; 10:127354696-127354696	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4482T>C; p.I1494I; 10:127418394-127418394	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2481T>C; p.N827N; 10:127110275-127110275	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - coding silent
c.3293A>T; p.E1098V; 10:127362136-127362136	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4630-3C>T; p.?; 10:127419663-127419663	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.3293A>T; p.E1098V; 10:127362136-127362136	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.4065A>G; p.K1355K; 10:127409042-127409042	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - coding silent
c.804A>T; p.L268F; 10:126999390-126999390	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3702C>T; p.T1234T; 10:127381326-127381326	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.4933C>T; p.L1645L; 10:127433364-127433364	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3625G>C; p.E1209Q; 10:127380094-127380094	breast	carcinoma	Substitution - Missense
c.4059+1G>A; p.?; 10:127404430-127404430	skin	malignant_melanoma	Unknown
c.835C>T; p.R279*; 10:126999421-126999421	ovary	carcinoma; serous_carcinoma	Substitution - Nonsense
c.836G>T; p.R279L; 10:126999422-126999422	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4127_4128CT>AG; p.T1376K; 10:127409104-127409105	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3187G>T; p.G1063C; 10:127354694-127354694	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1075G>T; p.D359Y; 10:127012311-127012311	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3187G>T; p.G1063C; 10:127354694-127354694	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.550C>T; p.L184F; 10:126996824-126996824	breast	carcinoma	Substitution - Missense
c.3845A>G; p.H1282R; 10:127384890-127384890	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3984C>T; p.I1328I; 10:127404354-127404354	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3984C>T; p.I1328I; 10:127404354-127404354	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4908C>T; p.F1636F; 10:127433339-127433339	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4559A>G; p.N1520S; 10:127418471-127418471	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2793C>T; p.F931F; 10:127248016-127248016	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2793C>T; p.F931F; 10:127248016-127248016	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3409G>C; p.E1137Q; 10:127373820-127373820	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.3408C>T; p.V1136V; 10:127373819-127373819	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4950C>T; p.V1650V; 10:127433381-127433381	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4346A>C; p.N1449T; 10:127410905-127410905	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.79G>T; p.E27*; 10:126970734-126970734	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.3670T>C; p.C1224R; 10:127381294-127381294	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5560C>T; p.R1854C; 10:127451389-127451389	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5560C>T; p.R1854C; 10:127451389-127451389	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5560C>T; p.R1854C; 10:127451389-127451389	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5548C>T; p.P1850S; 10:127451377-127451377	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.5548C>T; p.P1850S; 10:127451377-127451377	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4646G>A; p.R1549Q; 10:127419682-127419682	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1499C>T; p.P500L; 10:127026362-127026362	skin	malignant_melanoma	Substitution - Missense
c.3574A>G; p.N1192D; 10:127374176-127374176	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5113A>C; p.K1705Q; 10:127439142-127439142	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3586C>T; p.R1196C; 10:127374188-127374188	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4880G>A; p.S1627N; 10:127433311-127433311	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1574C>T; p.S525F; 10:127031662-127031662	skin	malignant_melanoma	Substitution - Missense
c.1698G>A; p.T566T; 10:127032169-127032169	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3131C>T; p.S1044L; 10:127343716-127343716	skin	malignant_melanoma	Substitution - Missense
c.3154C>T; p.L1052F; 10:127343739-127343739	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4646G>T; p.R1549L; 10:127419682-127419682	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3154C>T; p.L1052F; 10:127343739-127343739	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4113G>T; p.E1371D; 10:127409090-127409090	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3094T>G; p.F1032V; 10:127343679-127343679	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2127G>A; p.T709T; 10:127043153-127043153	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3165C>T; p.Y1055Y; 10:127354672-127354672	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.907C>T; p.R303C; 10:127000229-127000229	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.125A>G; p.Y42C; 10:126970780-126970780	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2527G>A; p.E843K; 10:127110321-127110321	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2527G>A; p.E843K; 10:127110321-127110321	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2527G>A; p.E843K; 10:127110321-127110321	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2527G>A; p.E843K; 10:127110321-127110321	liver	carcinoma	Substitution - Missense
c.2527G>A; p.E843K; 10:127110321-127110321	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2527G>A; p.E843K; 10:127110321-127110321	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2527G>A; p.E843K; 10:127110321-127110321	breast	carcinoma	Substitution - Missense
c.2527G>A; p.E843K; 10:127110321-127110321	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1492G>A; p.A498T; 10:127026355-127026355	breast	carcinoma	Substitution - Missense
c.2527G>A; p.E843K; 10:127110321-127110321	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1199C>T; p.P400L; 10:127018770-127018770	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1271T>C; p.V424A; 10:127023206-127023206	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2193A>T; p.V731V; 10:127052735-127052735	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.4044C>T; p.F1348F; 10:127404414-127404414	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.922G>A; p.E308K; 10:127000244-127000244	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1911G>A; p.R637R; 10:127037780-127037780	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.4739G>A; p.R1580K; 10:127425899-127425899	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1787C>T; p.T596I; 10:127032258-127032258	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3356G>A; p.R1119Q; 10:127362199-127362199	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.5374G>A; p.G1792R; 10:127447417-127447417	skin	malignant_melanoma	Substitution - Missense
c.1390-1G>A; p.?; 10:127024684-127024684	liver	carcinoma	Unknown
c.5374G>A; p.G1792R; 10:127447417-127447417	skin	malignant_melanoma	Substitution - Missense
c.1390-1G>A; p.?; 10:127024684-127024684	liver	carcinoma	Unknown
c.4964C>T; p.S1655L; 10:127433395-127433395	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1049C>T; p.P350L; 10:127008795-127008795	skin	malignant_melanoma	Substitution - Missense
c.4995C>T; p.D1665D; 10:127433426-127433426	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - coding silent
c.2472C>T; p.F824F; 10:127110266-127110266	skin	malignant_melanoma	Substitution - coding silent
c.5253C>T; p.S1751S; 10:127444182-127444182	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2595T>C; p.D865D; 10:127125508-127125508	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.717T>A; p.D239E; 10:126998199-126998199	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3188G>T; p.G1063V; 10:127354695-127354695	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4717C>T; p.P1573S; 10:127425877-127425877	NS	malignant_melanoma	Substitution - Missense
c.4717C>T; p.P1573S; 10:127425877-127425877	NS	malignant_melanoma	Substitution - Missense
c.5421C>T; p.S1807S; 10:127447464-127447464	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.5421C>T; p.S1807S; 10:127447464-127447464	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5349G>A; p.S1783S; 10:127444278-127444278	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1656C>T; p.I552I; 10:127031744-127031744	skin	malignant_melanoma	Substitution - coding silent
c.2862T>C; p.F954F; 10:127248085-127248085	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4797C>T; p.A1599A; 10:127425957-127425957	skin	malignant_melanoma	Substitution - coding silent
c.99A>T; p.G33G; 10:126970754-126970754	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.4457A>C; p.E1486A; 10:127418369-127418369	skin	malignant_melanoma	Substitution - Missense
c.3904G>A; p.E1302K; 10:127403094-127403094	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4307G>T; p.R1436L; 10:127410866-127410866	skin	malignant_melanoma	Substitution - Missense
c.397C>G; p.L133V; 10:126990527-126990527	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.4624G>A; p.E1542K; 10:127418536-127418536	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.4624G>A; p.E1542K; 10:127418536-127418536	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.4624G>A; p.E1542K; 10:127418536-127418536	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4624G>A; p.E1542K; 10:127418536-127418536	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.985+6C>G; p.?; 10:127000313-127000313	urinary_tract; bladder	carcinoma	Unknown

COSMIC somatic mutation [Top]