| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10006 |
Name | ABI1 |
Synonymous | abl-interactor 1;ABI1;abl-interactor 1 |
Definition | Abelson interactor 1|Abl-interactor protein 1 long|abl interactor 1|abl-binding protein 4|eps8 SH3 domain-binding protein|interactor protein AblBP4|nap1 binding protein|spectrin SH3 domain-binding protein 1 |
Position | 10p11.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | ABI1(h) --> abi1-isoform6(h) (expression). | BCAP(h) + abi1(h) <==> BCAP(h):abi1(h) (binding) | abi1(h) --> BCAP(h){pY513}{pY553}{pY570}{pY594}{pY694} (increase of phosphorylation) | abi1(h) + syntaxin1A(m.s.) <==> abi1(h):syntaxin1A(m.s.) (binding) | SNAP-25(m.s.) + abi1(h) <==> SNAP-25(m.s.):abi1(h) (binding) | abi1(h) + VAMP-2(m.s.) <==> abi1(h):VAMP-2(m.s.) (binding) | abi1(h) + WAVE-1(m.s.) <==> abi1(h):WAVE-1(m.s.) (binding) | NAP1(h) + PIR121(h) + WAVE2(h) + abi1(h) <==> NAP1(h):PIR121(h):WAVE2(h):abi1(h) (binding) | ABI1(h) --> abi1(h) (expression). | ABI1(h) --> abi1-isoform3(h) (expression). | ABI1(h) --> abi1-isoform4(h) (expression). | ABI1(h) --> abi1-isoform2(h) (expression). | ABI1(h) --> abi1-isoform5(h) (expression). | ABI1(h) --> abi1-isoform1(h) (expression). | ABI1(h) --> abi1-isoform7(h) (expression). | ABI1(h) --> abi1-isoform8(h) (expression). | ABI1(h) --> abi1-isoform9(h) (expression). | ABI1(h) --> abi1-isoform10(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 183 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 225 | Phosphoserine. | Swiss-Prot 53.0 | 333 | Phosphotyrosine. | Swiss-Prot 53.0 | 332 | Phosphotyrosine | 12522270 | Phospho.ELM 6.0 | 212 | Phosphotyrosine | 16497976 | Phospho.ELM 6.0 | 197 | Phosphotyrosine | 16497976 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr10 |
Promoter: 27189465 - 27191465 | Agilent_014791 |
chr10 |
Promoter: 27189465 - 27191465 | GSE27584 |
chr10 |
Promoter: 27189465 - 27191465 | GSE27584 |
chr10 |
Promoter: 27189465 - 27191465 | GSE27584 |
chr10 |
Promoter: 27189465 - 27191465 | GSE27584 |
chr10 |
Promoter: 27189465 - 27191465 | Agilent_014791_44K |