| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10006 |
Name | ABI1 |
Synonym | ABI-1|ABLBP4|E3B1|NAP1BP|SSH3BP|SSH3BP1;abl-interactor 1;ABI1;abl-interactor 1 |
Definition | Abelson interactor 1|Abl-interactor protein 1 long|abl interactor 1|abl-binding protein 4|eps8 SH3 domain-binding protein|interactor protein AblBP4|nap1 binding protein|spectrin SH3 domain-binding protein 1 |
Position | 10p11.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | E-cadherin signaling in the nascent adherens junction;PID Curated;200105 |
Pathway | Stabilization and expansion of the E-cadherin adherens junction;PID Curated;200155 |
Pathway | RAC1 signaling pathway;PID Curated;200190 |
Pathway | Regulation of RAC1 activity;PID Curated;200165 |
Pathway | ErbB1 downstream signaling;PID Curated;200113 |
Disease | Leukemia;FunDO |
Disease | Breast cancer;FunDO |
External Links | |
Links to Entrez Gene | 10006 |
Links to all GeneRIF Items | 10006 |
Links to iHOP | 10006 |
Sequence Information | |
Nucleotide Sequence | >10006 : length: 3725 GAGAAATAAACGCTCGCGAGAGAACGAGGTTCAGGCGGCTGCACGAAGGGGGTGGAGGGG GGCTGGAGAGAGTGAGGAGGAAGGGGAGGAGGTGCCGTCCCACAATACCAGGCGGGAGGG CGGGTAGGCGGTTTGTATCCGGGCTGTGAGGTGCTCGGAGCCTCGGCGGACCTTGCTGCC TCTGTCTCTTTAACGCGAGAGGAAGCGATGCAGAGGGGTGGAAAATGGCAGAGCTGCAGA TGTTACTAGAGGAGGAGATCCCGTCTGGCAAGAGGGCGCTGATCGAGAGTTACCAGAACC TGACTCGGGTGGCAGACTACTGTGAAAACAACTACATACAGGCTACAGACAAGAGAAAAG CTTTAGAGGAGACCAAAGCCTATACAACCCAATCTCTAGCTAGTGTTGCTTATCAAATAA ATGCATTGGCCAACAATGTACTCCAGTTGCTGGATATCCAAGCCTCTCAGCTTCGGAGAA TGGAGTCTTCCATCAATCATATCTCACAGACTGTGGATATTCATAAGGAGAAAGTGGCAC GAAGAGAGATTGGTATTTTGACAACAAATAAGAATACATCAAGAACTCACAAAATAATAG CACCTGCGAATATGGAGCGCCCTGTAAGGTATATTCGGAAACCTATCGATTACACAGTTC TGGATGATGTGGGCCATGGTGTCAAGTGGCTAAAAGCCAAGCATGGAAATAACCAGCCTG CAAGAACTGGCACACTGTCGAGAACAAATCCTCCTACTCAGAAACCGCCAAGTCCTCCCA TGTCAGGCCGGGGAACACTGGGACGGAATACTCCTTATAAAACCCTGGAACCTGTTAAAC CCCCAACAGTTCCTAATGACTATATGACCAGTCCTGCTAGGCTTGGAAGTCAGCATAGTC CAGGCAGGACAGCATCTTTAAATCAGAGACCAAGGACACACAGTGGAAGTAGTGGAGGAA GTGGAAGTCGAGAAAACAGTGGTAGCAGTAGTATTGGCATTCCCATTGCTGTGCCTACAC CTTCGCCACCCACTATTGGACCAGAAAACATTTCTGTCCCTCCTCCTTCTGGAGCTCCAC CAGCACCACCTCTGGCACCACTTCTCCCAGTGAGCACTGTGATAGCAGCCCCGGGCTCAG CTCCTGGTTCCCAGTATGGCACAATGACCAGGCAGATATCTCGACACAACTCTACTACTT CTTCGACATCTTCTGGTGGATACAGACGAACTCCCTCTGTGACTGCTCAATTTTCTGCTC AGCCTCATGTTAATGGAGGTCCACTTTATTCTCAAAATTCAATTTCTATTGCTCCACCCC CTCCCCCTATGCCTCAGTTGACTCCACAGATACCTCTCACAGGCTTCGTGGCCAGGGTGC AGGAAAACATTGCTGATAGTCCAACTCCACCGCCACCACCTCCACCAGATGACATTCCCA TGTTTGATGACTCTCCACCTCCCCCACCACCACCACCAGTGGATTATGAAGATGAGGAGG CTGCAGTAGTTCAGTATAATGATCCATATGCAGATGGGGATCCTGCTTGGGCCCCCAAGA ATTATATTGAGAAAGTTGTTGCAATATATGATTATACAAAAGACAAGGATGATGAGCTGT CATTTATGGAGGGTGCAATCATTTATGTTATAAAGAAGAATGATGATGGCTGGTATGAAG GAGTCTGCAATCGAGTGACTGGTCTGTTCCCTGGGAACTATGTTGAATCAATCATGCACT ATACTGATTAATTTTTTTTTTTCTTTTGAAGTAGATTCTTATTACTCAGTCATACTGTGG GACTATTATGGTTAACAGAACTGTCTTAATATGTTTTAAAATGTGCCCATATTTTCAGAA CATGCTGTTTTATTGGTAAATTGAATGTCTACCTGTAAGCATAAATCTTTGAGGCAGTTT ATGTATTGCTGAATAGCAATTTATACAAGAAGCTGTCCATAACTGATTATGCTTATGTAC TTACTTACACATTTTTAACTTTATGACCAGCCTAAATATTCTGGGGGAAGTGGGGTATAA TATTTAACGAATCATGATTCAGATTGTACCATTACATGTTTCAGTGCAGCATGGTTACTA ACGCTATGTCAGACTAATATTAAAATCAGAAAATTTAAATGCTGGTGCTGGTCAGACTTT TTTTGTTAGATTCTCTCATTTAAAAAAAATACTGTTTGTTTAAAGCATGCATAAAAATTT ATGTATTGAAATATACTTAAAAATTCAAGATGCTTCCCATTTGTGTAATATTTACCTGGA GGACTCGTACTTAGGTGTCTTAACGTGAATTGAGTCTCCAAGGTCTCCATGTGAAACAAG CAAAAAGAGAATTATCTGTAATGTTGTAATTTGTACCTAAGTTTTTTAATGAGTGAAATT TGCATTATAAACTTTTTCCATTCATAAATACATAAGTGAACCAAAGGTTTTTGTCCTTTC CTTCACTGATTTGCTTTAAAAAAAATAAAAGATAATGATTTATTGCAGAATTATGATTCT ATTTTCTCAATATGTTAACTTGGAAAAAAATTTTAGCCTTATCTTAATCTGTCCCAACAG CAATGTGACGGATTTTTGCAGATTCAAAATCTGCAATGGTTATTTACAAGTCAATCTACT GAATTCCTTTTTTAAATAATCTTTTGAAACTAAGAAAATGTGTCAAATTGTGTGCATTCA TTCTGTAGGTAAAATTCTTAAGGATTGCCATGTCAGTCCTTCAGTTGTACAGTGAACTGT TGTACACTGGTTCAATGAAAGGAAGTTAAAAGTACCTTTTACATATTGTAAAAGTGGATA CAGTTGATTTGTGAGTAGGCACTCTTTAATCCATTACCTGGCACTAGCAACATTAGAATT TTAAAATAAAATAATTGGGAAAGAAGGTGGGTCATGTATTAATCAGTGAACAGAGATTTA CCTAACCAACAGACTTGGATTGTCTTTTGACATAATCAAAATGCAACACATGCACTTTGT GTGTCTCCTCTTAATTGAAGGGAGGGCTGAGGGATGTTTTCTCTTCTTGTCTTGTGTATA ATTCTCTATTGCTTAGGATATTAAAGTAGAGCACTCAAGTGTGGGTTTCTGTGTTATTGA GGATTTGTTTGGAATTCAAATTACAGTTATGTACTGGATGCTACAGACTTATAACAGCAT AGTGAATGGTAAGACTAGTGCAAAACAGTTATTTCTGAAAATTAAAGACCATTATTGCTA CCAAATCAATGTGACTATTTCATATGCATTTTGCCTTTGTTAATTTTAAACAAACAAAGT ATCATTAGTGATCAGCTAGCTACCTTCTACTTTCCATTTTTCAAGTGGATTGTTCTCTTA ATTTGTATATAACCTGTTGTCTAAATTTTATGTACAGTCTTTTATAATAAACCATTCTCC TATATGAAATTTTGGATACTGTTAAAATATAACTCATGTGGACTTCAATGCAGACTTCAC ATTTTTCTGACCTTTACTCCTACGGTAAATCAAGACAAACCATTTGAATTTTAACATTGG TTATTTATTTGTGTAATGGCCTTACATGTGGATATTAACAGTGTAAACAATACCACATAT AACCATCAAGATACCTTGATTATAATTTATAGGACTAGAATGACAGATTCAGGTGGTTTA TTAATTACATTTAAAAAGTTTTCTGAAAAAACTTTTGCAATAAAAAAAAATAAATTGCCC ATCAA |
Protein Sequence | >10006 : length: 508 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVI AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI SIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVD YEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKND DGWYEGVCNRVTGLFPGNYVESIMHYTD |