| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10006 |
Name | ABI1 |
Synonymous | abl-interactor 1;ABI1;abl-interactor 1 |
Definition | Abelson interactor 1|Abl-interactor protein 1 long|abl interactor 1|abl-binding protein 4|eps8 SH3 domain-binding protein|interactor protein AblBP4|nap1 binding protein|spectrin SH3 domain-binding protein 1 |
Position | 10p11.2 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.958C>T; p.R320*; 10:26759182-26759182 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.547A>G; p.S183G; 10:26770276-26770276 |
skin | malignant_melanoma | Substitution - Missense |
c.1235C>T; p.P412L; 10:26751714-26751714 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.315A>G; p.A105A; 10:26777212-26777212 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.1096C>T; p.P366S; 10:26755724-26755724 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.33G>A; p.E11E; 10:26860831-26860831 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.1461C>T; p.V487V; 10:26748636-26748636 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.1480C>A; p.L494M; 10:26748617-26748617 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.477+1G>T; p.?; 10:26771074-26771074 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Unknown |
c.1297G>A; p.D433N; 10:26751652-26751652 |
upper_aerodigestive_tract; mouth | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.1059A>T; p.P353P; 10:26759081-26759081 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.909G>A; p.P303P; 10:26759231-26759231 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.909G>A; p.P303P; 10:26759231-26759231 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.830C>T; p.S277F; 10:26763951-26763951 |
skin | malignant_melanoma | Substitution - Missense |
c.209A>G; p.N70S; 10:26823214-26823214 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.530C>T; p.P177L; 10:26770293-26770293 |
skin | malignant_melanoma | Substitution - Missense |
c.719+1G>A; p.?; 10:26768851-26768851 |
skin; extremity | malignant_melanoma | Unknown |
c.1265A>C; p.E422A; 10:26751684-26751684 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.121A>G; p.T41A; 10:26823302-26823302 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.392A>G; p.E131G; 10:26777135-26777135 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.847G>A; p.G283R; 10:26763934-26763934 |
skin | malignant_melanoma | Substitution - Missense |
c.412C>T; p.R138W; 10:26777115-26777115 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.254G>A; p.R85K; 10:26823169-26823169 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.720-9delT; p.?; 10:26765327-26765327 |
stomach | carcinoma; diffuse_adenocarcinoma | Unknown |
c.390G>C; p.M130I; 10:26777137-26777137 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.371T>C; p.I124T; 10:26777156-26777156 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.1118C>T; p.T373I; 10:26755702-26755702 |
oesophagus | carcinoma; adenocarcinoma | Substitution - Missense |
c.419C>T; p.P140L; 10:26777108-26777108 |
skin | malignant_melanoma | Substitution - Missense |
c.457G>T; p.V153F; 10:26777070-26777070 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.1240C>T; p.P414S; 10:26751709-26751709 |
breast | carcinoma | Substitution - Missense |
c.95A>G; p.Y32C; 10:26860769-26860769 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.1163delA; p.N388fs*41; 10:26755657-26755657 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.1490G>T; p.G497V; 10:26748607-26748607 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.165C>A; p.T55T; 10:26823258-26823258 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.1252_1254delCCA; p.P418delP; 10:26751695-26751697 |
skin | malignant_melanoma | Deletion - In frame |
c.980C>T; p.S327L; 10:26759160-26759160 |
breast | carcinoma | Substitution - Missense |
c.478C>T; p.H160Y; 10:26770345-26770345 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.516G>A; p.S172S; 10:26770307-26770307 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.1335G>T; p.K445N; 10:26751614-26751614 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.1335G>T; p.K445N; 10:26751614-26751614 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.1335G>T; p.K445N; 10:26751614-26751614 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.1335G>T; p.K445N; 10:26751614-26751614 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.1335G>T; p.K445N; 10:26751614-26751614 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.74A>G; p.N25S; 10:26860790-26860790 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.1187C>T; p.P396L; 10:26751762-26751762 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.93C>T; p.D31D; 10:26860771-26860771 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.478-1G>T; p.?; 10:26770346-26770346 |
lung | carcinoma; squamous_cell_carcinoma | Unknown |
c.316C>T; p.R106*; 10:26777211-26777211 |
stomach | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.919C>A; p.P307T; 10:26759221-26759221 |
stomach | carcinoma; intestinal_adenocarcinoma | Substitution - Missense |
c.1374A>G; p.T458T; 10:26748723-26748723 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.118-1G>A; p.?; 10:26823306-26823306 |
lung | carcinoma; adenocarcinoma | Unknown |
c.802C>A; p.P268T; 10:26765236-26765236 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.845C>A; p.S282Y; 10:26763936-26763936 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.720-9delT; p.?; 10:26765327-26765327 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Unknown |
c.914C>T; p.S305L; 10:26759226-26759226 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.317G>A; p.R106Q; 10:26777210-26777210 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.619C>T; p.P207S; 10:26768952-26768952 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.109T>C; p.Y37H; 10:26860755-26860755 |
skin | malignant_melanoma | Substitution - Missense |
c.330T>C; p.G110G; 10:26777197-26777197 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.38C>A; p.P13Q; 10:26860826-26860826 |
thyroid | other; neoplasm | Substitution - Missense |
c.1194A>G; p.P398P; 10:26751755-26751755 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.621A>G; p.P207P; 10:26768950-26768950 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.395G>A; p.R132H; 10:26777132-26777132 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.1357G>A; p.A453T; 10:26748740-26748740 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.1252C>T; p.P418S; 10:26751697-26751697 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.895G>T; p.V299L; 10:26763886-26763886 |
breast | carcinoma | Substitution - Missense |