| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5742 |
Name | PTGS1 |
Synonymous | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase);PTGS1;prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
Definition | PGH synthase 1|cyclooxygenase-1|prostaglandin G/H synthase 1|prostaglandin H2 synthase 1 |
Position | 9q32-q33.3 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.529G>A; p.A177T; 9:122381403-122381403 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.639C>A; p.G213G; 9:122381513-122381513 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.610T>A; p.F204I; 9:122381484-122381484 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.232C>T; p.R78W; 9:122378453-122378453 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.1610C>T; p.P537L; 9:122392354-122392354 |
skin; neck | malignant_melanoma | Substitution - Missense |
c.343G>T; p.V115L; 9:122378564-122378564 |
upper_aerodigestive_tract; larynx | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.158G>A; p.R53H; 9:122377962-122377962 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.1723C>T; p.P575S; 9:122392467-122392467 |
skin; ear | carcinoma; squamous_cell_carcinoma | Substitution - Missense |