| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3630 |
Name | INS |
Synonymous | insulin;INS;insulin |
Definition | preproinsulin|proinsulin |
Position | 11p15.5 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.280C>A; p.Q94K; 11:2159905-2159905 |
kidney | carcinoma; papillary_renal_cell_carcinoma | Substitution - Missense |
c.86A>C; p.H29P; 11:2160886-2160886 |
breast | carcinoma | Substitution - Missense |
c.16C>T; p.R6C; 11:2160956-2160956 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.133G>A; p.E45K; 11:2160839-2160839 |
skin | malignant_melanoma | Substitution - Missense |
c.333G>A; p.*111*; 11:2159852-2159852 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - coding silent |
c.129C>T; p.C43C; 11:2160843-2160843 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - coding silent |
c.129C>T; p.C43C; 11:2160843-2160843 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia | Substitution - coding silent |
c.129C>T; p.C43C; 11:2160843-2160843 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related | Substitution - coding silent |
c.159G>A; p.K53K; 11:2160813-2160813 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.94G>C; p.G32R; 11:2160878-2160878 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.175G>A; p.E59K; 11:2160797-2160797 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.318G>T; p.E106D; 11:2159867-2159867 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.228C>G; p.S76R; 11:2159957-2159957 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.246G>T; p.L82L; 11:2159939-2159939 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - coding silent |
c.34G>T; p.A12S; 11:2160938-2160938 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.105G>A; p.L35L; 11:2160867-2160867 |
skin | malignant_melanoma | Substitution - coding silent |
c.276G>A; p.V92V; 11:2159909-2159909 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.277G>A; p.E93K; 11:2159908-2159908 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.121C>T; p.L41L; 11:2160851-2160851 |
prostate | carcinoma; adenocarcinoma | Substitution - coding silent |
c.255C>T; p.S85S; 11:2159930-2159930 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.217G>T; p.G73C; 11:2159968-2159968 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |