| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3630 |
Name | INS |
Synonymous | insulin;INS;insulin |
Definition | preproinsulin|proinsulin |
Position | 11p15.5 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
DDOST | REACTOME; |
in same component |
GRB10 | NCI_NATURE; |
in same component |
GRB10 | REACTOME; |
in same component |
GRB14 | NCI_NATURE; |
in same component |
INSR | NCI_NATURE; |
in same component |
INSR | REACTOME; |
in same component |
IRS1 | NCI_NATURE; |
in same component |
NCK2 | NCI_NATURE; |
in same component |
PDPK1 | NCI_NATURE; |
in same component |
PTPN11 | NCI_NATURE; |
in same component |
PTPN1 | NCI_NATURE; |
in same component |
RPL10 | REACTOME; |
in same component |
RPL12 | REACTOME; |
in same component |
RPL13A | REACTOME; |
in same component |
RPL13 | REACTOME; |
in same component |
RPL14 | REACTOME; |
in same component |
RPL17 | REACTOME; |
in same component |
RPL18A | REACTOME; |
in same component |
RPL18 | REACTOME; |
in same component |
RPL21 | REACTOME; |
in same component |
RPL22 | REACTOME; |
in same component |
RPL26L1 | REACTOME; |
in same component |
RPL27A | REACTOME; |
in same component |
RPL28 | REACTOME; |
in same component |
RPL29 | REACTOME; |
in same component |
RPL34 | REACTOME; |
in same component |
RPL35A | REACTOME; |
in same component |
RPL35 | REACTOME; |
in same component |
RPL36 | REACTOME; |
in same component |
RPL3 | REACTOME; |
in same component |
RPL3L | REACTOME; |
in same component |
RPL4 | REACTOME; |
in same component |
RPL5 | REACTOME; |
in same component |
RPL6 | REACTOME; |
in same component |
RPL7 | REACTOME; |
in same component |
RPL9 | REACTOME; |
in same component |
RPLP0 | REACTOME; |
in same component |
RPLP1 | REACTOME; |
in same component |
RPLP2 | REACTOME; |
in same component |
RPN1 | REACTOME; |
in same component |
RPN2 | REACTOME; |
in same component |
RPS10 | REACTOME; |
in same component |
RPS12 | REACTOME; |
in same component |
RPS17 | REACTOME; |
in same component |
RPS19 | REACTOME; |
in same component |
RPS21 | REACTOME; |
in same component |
RPS27 | REACTOME; |
in same component |
RPS2 | REACTOME; |
in same component |
RPS3 | REACTOME; |
in same component |
RPS4Y1 | REACTOME; |
in same component |
RPS5 | REACTOME; |
in same component |
RPS9 | REACTOME; |
in same component |
RPSA | REACTOME; |
in same component |
SEC61B | REACTOME; |
in same component |
SEC61G | REACTOME; |
in same component |
SHC1 | NCI_NATURE; |
in same component |
SHC1 | REACTOME; |
in same component |
SOS1 | NCI_NATURE; |
in same component |
SRP14 | REACTOME; |
in same component |
SRP19 | REACTOME; |
in same component |
SRP54 | REACTOME; |
in same component |
SRP68 | REACTOME; |
in same component |
SRP72 | REACTOME; |
in same component |
SRP9 | REACTOME; |
in same component |
SRPRB | REACTOME; |
in same component |
SRPR | REACTOME; |
in same component |
SSR1 | REACTOME; |
in same component |
SSR2 | REACTOME; |
in same component |
SSR3 | REACTOME; |
in same component |
SSR4 | REACTOME; |
in same component |
TRAM1 | REACTOME; |
interacts with |
CPE | HPRD; |
interacts with |
CTSB | HPRD; |
interacts with |
CTSD | HPRD; |
interacts with |
CTSE | HPRD; |
interacts with |
GCK | HPRD; |
interacts with |
HLA-DQA2 | HPRD; |
interacts with |
HLA-DQB1 | HPRD; |
interacts with |
IGF1R | HPRD; |
interacts with |
IGFBP7 | BIOGRID; |
interacts with |
IGFBP7 | HPRD; |
interacts with |
INSR | HPRD; |
interacts with |
MLL | BIOGRID; |
interacts with |
NOV | BIOGRID; |
interacts with |
NOV | HPRD; |
interacts with |
RB1 | HPRD; |
interacts with |
SYTL4 | HPRD; |
interacts with |
TXNDC17 | BIOGRID; |
interacts with |
TXNDC17 | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
ATF2 | NCI_NATURE; |
metabolic catalysis |
FOXA1 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
DDOST | REACTOME; |
reacts with |
GRB10 | NCI_NATURE; |
reacts with |
GRB10 | REACTOME; |
reacts with |
GRB14 | NCI_NATURE; |
reacts with |
INPP5D | NCI_NATURE; |
reacts with |
INS | NCI_NATURE; |
reacts with |
INS | REACTOME; |
reacts with |
INSR | NCI_NATURE; |
reacts with |
INSR | REACTOME; |
reacts with |
IRS1 | NCI_NATURE; |
reacts with |
NCK2 | NCI_NATURE; |
reacts with |
PDPK1 | NCI_NATURE; |
reacts with |
PTPN11 | NCI_NATURE; |
reacts with |
PTPN1 | NCI_NATURE; |
reacts with |
RPL10 | REACTOME; |
reacts with |
RPL12 | REACTOME; |
reacts with |
RPL13A | REACTOME; |
reacts with |
RPL13 | REACTOME; |
reacts with |
RPL14 | REACTOME; |
reacts with |
RPL17 | REACTOME; |
reacts with |
RPL18A | REACTOME; |
reacts with |
RPL18 | REACTOME; |
reacts with |
RPL21 | REACTOME; |
reacts with |
RPL22 | REACTOME; |
reacts with |
RPL26L1 | REACTOME; |
reacts with |
RPL27A | REACTOME; |
reacts with |
RPL28 | REACTOME; |
reacts with |
RPL29 | REACTOME; |
reacts with |
RPL34 | REACTOME; |
reacts with |
RPL35A | REACTOME; |
reacts with |
RPL35 | REACTOME; |
reacts with |
RPL36 | REACTOME; |
reacts with |
RPL3 | REACTOME; |
reacts with |
RPL3L | REACTOME; |
reacts with |
RPL4 | REACTOME; |
reacts with |
RPL5 | REACTOME; |
reacts with |
RPL6 | REACTOME; |
reacts with |
RPL7 | REACTOME; |
reacts with |
RPL9 | REACTOME; |
reacts with |
RPLP0 | REACTOME; |
reacts with |
RPLP1 | REACTOME; |
reacts with |
RPLP2 | REACTOME; |
reacts with |
RPN1 | REACTOME; |
reacts with |
RPN2 | REACTOME; |
reacts with |
RPS10 | REACTOME; |
reacts with |
RPS12 | REACTOME; |
reacts with |
RPS17 | REACTOME; |
reacts with |
RPS19 | REACTOME; |
reacts with |
RPS21 | REACTOME; |
reacts with |
RPS27 | REACTOME; |
reacts with |
RPS2 | REACTOME; |
reacts with |
RPS3 | REACTOME; |
reacts with |
RPS4Y1 | REACTOME; |
reacts with |
RPS5 | REACTOME; |
reacts with |
RPS9 | REACTOME; |
reacts with |
RPSA | REACTOME; |
reacts with |
SEC61B | REACTOME; |
reacts with |
SEC61G | REACTOME; |
reacts with |
SHC1 | NCI_NATURE; |
reacts with |
SHC1 | REACTOME; |
reacts with |
SOS1 | NCI_NATURE; |
reacts with |
SRP14 | REACTOME; |
reacts with |
SRP19 | REACTOME; |
reacts with |
SRP54 | REACTOME; |
reacts with |
SRP68 | REACTOME; |
reacts with |
SRP72 | REACTOME; |
reacts with |
SRP9 | REACTOME; |
reacts with |
SRPRB | REACTOME; |
reacts with |
SRPR | REACTOME; |
reacts with |
SSR1 | REACTOME; |
reacts with |
SSR2 | REACTOME; |
reacts with |
SSR3 | REACTOME; |
reacts with |
SSR4 | REACTOME; |
reacts with |
SYT5 | REACTOME; |
reacts with |
TRAM1 | REACTOME; |
reacts with |
VAMP2 | REACTOME; |
state change |
AKT1 | NCI_NATURE; |
state change |
CPE | REACTOME; |
state change |
ERO1L | REACTOME; |
state change |
INS | REACTOME; |
state change |
INSR | REACTOME; |
state change |
MAFA | REACTOME; |
state change |
MYO5A | REACTOME; |
state change |
NKX2-2 | REACTOME; |
state change |
PCSK2 | REACTOME; |
state change |
PDX1 | REACTOME; |
state change |
PTPN1 | NCI_NATURE; |
state change |
PTPRA | NCI_NATURE; |
state change |
SHC1 | REACTOME; |
state change |
SLC30A7 | REACTOME; |
state change |
SRP14 | REACTOME; |
state change |
SRP19 | REACTOME; |
state change |
SRP54 | REACTOME; |
state change |
SRP68 | REACTOME; |
state change |
SRP72 | REACTOME; |
state change |
SRP9 | REACTOME; |
state change |
SRPRB | REACTOME; |
state change |
SRPR | REACTOME; |
state change |
VAMP2 | REACTOME; |