Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

3561

Name

IL2RG

Synonymous

interleukin 2 receptor, gamma;IL2RG;interleukin 2 receptor, gamma

Definition

CD132 antigen|IL-2 receptor subunit gamma|IL-2R subunit gamma|common cytokine receptor gamma chain|cytokine receptor common subunit gamma|gammaC

Position

Xq13.1

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.511G>T; p.E171*; 23:71110239-71110239

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.665G>A; p.R222H; 23:71109320-71109320

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.9G>T; p.K3N; 23:71111531-71111531

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.176A>T; p.E59V; 23:71110990-71110990

 livercarcinomaSubstitution - Missense

c.970G>C; p.D324H; 23:71107876-71107876

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.763C>T; p.P255S; 23:71108690-71108690

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.176A>T; p.E59V; 23:71110990-71110990

 livercarcinomaSubstitution - Missense

c.359delA; p.K120fs*27; 23:71110599-71110599

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1082_1083insC; p.C362fs*7; 23:71107763-71107764

 large_intestinecarcinoma; adenocarcinomaInsertion - Frameshift

c.1082_1083insC; p.C362fs*7; 23:71107763-71107764

 large_intestinecarcinoma; adenocarcinomaInsertion - Frameshift

c.1082_1083insC; p.C362fs*7; 23:71107763-71107764

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.100G>T; p.E34*; 23:71111440-71111440

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.364A>T; p.I122F; 23:71110594-71110594

 bonechondrosarcomaSubstitution - Missense

c.100G>T; p.E34*; 23:71111440-71111440

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.757G>A; p.E253K; 23:71109228-71109228

 skinmalignant_melanomaSubstitution - Missense

c.306C>A; p.C102*; 23:71110652-71110652

 skinmalignant_melanomaSubstitution - Nonsense

c.1000G>C; p.E334Q; 23:71107846-71107846

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1098G>A; p.K366K; 23:71107748-71107748

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1098G>A; p.K366K; 23:71107748-71107748

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1098G>A; p.K366K; 23:71107748-71107748

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.95G>T; p.G32V; 23:71111445-71111445

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.831C>T; p.L277L; 23:71108622-71108622

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1081C>T; p.P361S; 23:71107765-71107765

 thyroidcarcinomaSubstitution - Missense

c.915G>A; p.G305G; 23:71108286-71108286

 skinmalignant_melanomaSubstitution - coding silent

c.624C>T; p.F208F; 23:71109361-71109361

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.351G>A; p.L117L; 23:71110607-71110607

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.172C>A; p.P58T; 23:71110994-71110994

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.652C>T; p.R218C; 23:71109333-71109333

 pancreasNSSubstitution - Missense

c.1075G>C; p.A359P; 23:71107771-71107771

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.925G>T; p.A309S; 23:71107921-71107921

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.266A>T; p.Y89F; 23:71110900-71110900

 breastcarcinomaSubstitution - Missense

c.850G>T; p.E284*; 23:71108603-71108603

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.994G>A; p.V332I; 23:71107852-71107852

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1044C>T; p.A348A; 23:71107802-71107802

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - coding silent

c.621G>A; p.K207K; 23:71109364-71109364

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.866G>A; p.R289Q; 23:71108335-71108335

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.854+2T>G; p.?; 23:71108597-71108597

 lungcarcinoma; squamous_cell_carcinomaUnknown

c.221_222GG>TA; p.W74>?; 23:71110944-71110945

 lungcarcinoma; adenocarcinomaComplex

c.857C>A; p.T286K; 23:71108344-71108344

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.733C>T; p.H245Y; 23:71109252-71109252

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.149T>A; p.L50H; 23:71111017-71111017

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.372C>T; p.L124L; 23:71110586-71110586

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.432G>T; p.Q144H; 23:71110526-71110526

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.670C>T; p.R224W; 23:71109315-71109315

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.82C>G; p.L28V; 23:71111458-71111458

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.597A>T; p.E199D; 23:71109388-71109388

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.923C>T; p.S308L; 23:71108278-71108278

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.570G>T; p.R190R; 23:71110180-71110180

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.923C>T; p.S308L; 23:71108278-71108278

 endometriumcarcinoma; serous_carcinomaSubstitution - Missense

c.267T>C; p.Y89Y; 23:71110899-71110899

 skinmalignant_melanomaSubstitution - coding silent

c.53T>C; p.L18P; 23:71111487-71111487

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.1082delC; p.P361fs*5; 23:71107764-71107764

 pancreascarcinoma; acinar_carcinomaDeletion - Frameshift

c.1082delC; p.P361fs*5; 23:71107764-71107764

 large_intestine; rectumcarcinoma; adenocarcinomaDeletion - Frameshift

c.1082delC; p.P361fs*5; 23:71107764-71107764

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1082delC; p.P361fs*5; 23:71107764-71107764

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1082delC; p.P361fs*5; 23:71107764-71107764

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.1082delC; p.P361fs*5; 23:71107764-71107764

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1082delC; p.P361fs*5; 23:71107764-71107764

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.1082delC; p.P361fs*5; 23:71107764-71107764

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1082delC; p.P361fs*5; 23:71107764-71107764

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.858G>A; p.T286T; 23:71108343-71108343

 prostatecarcinomaSubstitution - coding silent

c.858G>A; p.T286T; 23:71108343-71108343

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.727C>T; p.P243S; 23:71109258-71109258

 skinmalignant_melanomaSubstitution - Missense

c.59G>C; p.G20A; 23:71111481-71111481

 skinmalignant_melanomaSubstitution - Missense

c.995T>C; p.V332A; 23:71107851-71107851

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1036C>T; p.P346S; 23:71107810-71107810

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.438A>G; p.L146L; 23:71110520-71110520

 skinmalignant_melanomaSubstitution - coding silent

c.501A>T; p.E167D; 23:71110249-71110249

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.316C>A; p.L106I; 23:71110642-71110642

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.276G>T; p.K92N; 23:71110682-71110682

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.685C>T; p.P229S; 23:71109300-71109300

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.643G>A; p.G215R; 23:71109342-71109342

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.841T>G; p.F281V; 23:71108612-71108612

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.727C>A; p.P243T; 23:71109258-71109258

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.238C>T; p.P80S; 23:71110928-71110928

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.795C>A; p.I265I; 23:71108658-71108658

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.577T>A; p.W193R; 23:71110173-71110173

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1043C>A; p.A348D; 23:71107803-71107803

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1010delC; p.P337fs*29; 23:71107836-71107836

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.448A>C; p.N150H; 23:71110510-71110510

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1010delC; p.P337fs*29; 23:71107836-71107836

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.210G>A; p.M70I; 23:71110956-71110956

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.178G>A; p.V60I; 23:71110988-71110988

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.6G>A; p.L2L; 23:71111534-71111534

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.614G>T; p.R205I; 23:71109371-71109371

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.788T>C; p.V263A; 23:71108665-71108665

 breastcarcinomaSubstitution - Missense