| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3561 |
Name | IL2RG |
Synonym | CD132|CIDX|IL-2RG|IMD4|P64|SCIDX|SCIDX1;interleukin 2 receptor, gamma;IL2RG;interleukin 2 receptor, gamma |
Definition | CD132 antigen|IL-2 receptor subunit gamma|IL-2R subunit gamma|common cytokine receptor gamma chain|cytokine receptor common subunit gamma|gammaC |
Position | Xq13.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | IL2 signaling events mediated by STAT5;PID Curated;200158 |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | IL4-mediated signaling events;PID Curated;200018 |
Pathway | il-2 receptor beta chain in t cell activation;PID BioCarta;100129 |
Pathway | il 4 signaling pathway;PID BioCarta;100127 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | Downstream signaling in naive CD8+ T cells;PID Curated;200184 |
Pathway | il-7 signal transduction;PID BioCarta;100125 |
Pathway | Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630 |
Pathway | IL2 signaling events mediated by PI3K;PID Curated;200099 |
Pathway | IL2-mediated signaling events;PID Curated;200082 |
Pathway | IL12-mediated signaling events;PID Curated;200034 |
Pathway | il 2 signaling pathway;PID BioCarta;100130 |
Pathway | Primary immunodeficiency;KEGG PATHWAY;hsa05340 |
Disease | Embryoma;FunDO |
Disease | Combined immunodeficiency, X-linked, moderate;OMIM |
Disease | Severe combined immunodeficiency, X-linked;OMIM |
Disease | Immune system diseases;KEGG DISEASE |
Disease | T-B+ Severe combined immunodeficiencies;KEGG DISEASE;H00091 |
Disease | Leukemia;FunDO |
Disease | Primary immunodeficiency;KEGG DISEASE |
Disease | Immunologic deficiency syndrome;FunDO |
External Links | |
Links to Entrez Gene | 3561 |
Links to all GeneRIF Items | 3561 |
Links to iHOP | 3561 |
Sequence Information | |
Nucleotide Sequence | >3561 : length: 1560 AGAGGAAACGTGTGGGTGGGGAGGGGTAGTGGGTGAGGGACCCAGGTTCCTGACACAGAC AGACTACACCCAGGGAATGAAGAGCAAGCGCCATGTTGAAGCCATCATTACCATTCACAT CCCTCTTATTCCTGCAGCTGCCCCTGCTGGGAGTGGGGCTGAACACGACAATTCTGACGC CCAATGGGAATGAAGACACCACAGCTGATTTCTTCCTGACCACTATGCCCACTGACTCCC TCAGTGTTTCCACTCTGCCCCTCCCAGAGGTTCAGTGTTTTGTGTTCAATGTCGAGTACA TGAATTGCACTTGGAACAGCAGCTCTGAGCCCCAGCCTACCAACCTCACTCTGCATTATT GGTACAAGAACTCGGATAATGATAAAGTCCAGAAGTGCAGCCACTATCTATTCTCTGAAG AAATCACTTCTGGCTGTCAGTTGCAAAAAAAGGAGATCCACCTCTACCAAACATTTGTTG TTCAGCTCCAGGACCCACGGGAACCCAGGAGACAGGCCACACAGATGCTAAAACTGCAGA ATCTGGTGATCCCCTGGGCTCCAGAGAACCTAACACTTCACAAACTGAGTGAATCCCAGC TAGAACTGAACTGGAACAACAGATTCTTGAACCACTGTTTGGAGCACTTGGTGCAGTACC GGACTGACTGGGACCACAGCTGGACTGAACAATCAGTGGATTATAGACATAAGTTCTCCT TGCCTAGTGTGGATGGGCAGAAACGCTACACGTTTCGTGTTCGGAGCCGCTTTAACCCAC TCTGTGGAAGTGCTCAGCATTGGAGTGAATGGAGCCACCCAATCCACTGGGGGAGCAATA CTTCAAAAGAGAATCCTTTCCTGTTTGCATTGGAAGCCGTGGTTATCTCTGTTGGCTCCA TGGGATTGATTATCAGCCTTCTCTGTGTGTATTTCTGGCTGGAACGGACGATGCCCCGAA TTCCCACCCTGAAGAACCTAGAGGATCTTGTTACTGAATACCACGGGAACTTTTCGGCCT GGAGTGGTGTGTCTAAGGGACTGGCTGAGAGTCTGCAGCCAGACTACAGTGAACGACTCT GCCTCGTCAGTGAGATTCCCCCAAAAGGAGGGGCCCTTGGGGAGGGGCCTGGGGCCTCCC CATGCAACCAGCATAGCCCCTACTGGGCCCCCCCATGTTACACCCTAAAGCCTGAAACCT GAACCCCAATCCTCTGACAGAAGAACCCCAGGGTCCTGTAGCCCTAAGTGGTACTAACTT TCCTTCATTCAACCCACCTGCGTCTCATACTCACCTCACCCCACTGTGGCTGATTTGGAA TTTTGTGCCCCCATGTAAGCACCCCTTCATTTGGCATTCCCCACTTGAGAATTACCCTTT TGCCCCGAACATGTTTTTCTTCTCCCTCAGTCTGGCCCTTCCTTTTCGCAGGATTCTTCC TCCCTCCCTCTTTCCCTCCCTTCCTCTTTCCATCTACCCTCCGATTGTTCCTGAACCGAT GAGAAATAAAGTTTCTGTTGATAATCATCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
Protein Sequence | >3561 : length: 369 MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPEV QCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKK EIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLN HCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEW SHPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLV TEYHGNFSAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAP PCYTLKPET |