| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3561 |
Name | IL2RG |
Synonymous | interleukin 2 receptor, gamma;IL2RG;interleukin 2 receptor, gamma |
Definition | CD132 antigen|IL-2 receptor subunit gamma|IL-2R subunit gamma|common cytokine receptor gamma chain|cytokine receptor common subunit gamma|gammaC |
Position | Xq13.1 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
DOK2 | NCI_NATURE; |
in same component |
FES | NCI_NATURE; |
in same component |
FYN | NCI_NATURE; |
in same component |
GAB2 | NCI_NATURE; |
in same component |
IL2 | NCI_NATURE; |
in same component |
IL2 | REACTOME; |
in same component |
IL2RA | NCI_NATURE; |
in same component |
IL2RA | REACTOME; |
in same component |
IL2RB | NCI_NATURE; |
in same component |
IL2RB | REACTOME; |
in same component |
IL4 | NCI_NATURE; |
in same component |
IL4R | NCI_NATURE; |
in same component |
INPP5D | NCI_NATURE; |
in same component |
IRS1 | NCI_NATURE; |
in same component |
IRS2 | NCI_NATURE; |
in same component |
JAK1 | NCI_NATURE; |
in same component |
JAK1 | REACTOME; |
in same component |
JAK3 | NCI_NATURE; |
in same component |
JAK3 | REACTOME; |
in same component |
LCK | NCI_NATURE; |
in same component |
PIK3CA | NCI_NATURE; |
in same component |
PIK3R1 | NCI_NATURE; |
in same component |
PTK2B | NCI_NATURE; |
in same component |
PTPN11 | NCI_NATURE; |
in same component |
PTPN6 | NCI_NATURE; |
in same component |
SHC1 | NCI_NATURE; |
in same component |
SHC1 | REACTOME; |
in same component |
SOCS1 | NCI_NATURE; |
in same component |
SOS1 | NCI_NATURE; |
in same component |
SYK | NCI_NATURE; |
in same component |
SYK | REACTOME; |
interacts with |
AXL | HPRD; |
interacts with |
CAPNS1 | BIOGRID; |
interacts with |
CAPNS1 | HPRD; |
interacts with |
ICAM1 | HPRD; |
interacts with |
IL15 | HPRD; |
interacts with |
IL15RA | HPRD; |
interacts with |
IL2 | HPRD; |
interacts with |
IL2RB | HPRD; |
interacts with |
IL4 | HPRD; |
interacts with |
IL4R | HPRD; |
interacts with |
IL7 | HPRD; |
interacts with |
IL7R | HPRD; |
interacts with |
IL9R | HPRD; |
interacts with |
JAK1 | HPRD; |
interacts with |
JAK3 | BIOGRID; |
interacts with |
JAK3 | HPRD; |
interacts with |
SHB | BIOGRID; |
interacts with |
SHB | HPRD; |
interacts with |
SHC1 | BIOGRID; |
interacts with |
SHC1 | HPRD; |
interacts with |
STAT1 | HPRD; |
interacts with |
STAT5A | HPRD; |
interacts with |
WWP1 | HPRD; |
interacts with |
WWP2 | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
IL2 | NCI_NATURE; |
metabolic catalysis |
IL2RA | NCI_NATURE; |
metabolic catalysis |
IL2RB | NCI_NATURE; |
metabolic catalysis |
IL2RG | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
DOK2 | NCI_NATURE; |
reacts with |
FES | NCI_NATURE; |
reacts with |
FYN | NCI_NATURE; |
reacts with |
GAB2 | NCI_NATURE; |
reacts with |
IL2 | NCI_NATURE; |
reacts with |
IL2 | REACTOME; |
reacts with |
IL2RA | NCI_NATURE; |
reacts with |
IL2RA | REACTOME; |
reacts with |
IL2RB | NCI_NATURE; |
reacts with |
IL2RB | REACTOME; |
reacts with |
IL2RG | NCI_NATURE; |
reacts with |
IL2RG | REACTOME; |
reacts with |
IL4 | NCI_NATURE; |
reacts with |
IL4R | NCI_NATURE; |
reacts with |
INPP5D | NCI_NATURE; |
reacts with |
IRS1 | NCI_NATURE; |
reacts with |
IRS2 | NCI_NATURE; |
reacts with |
JAK1 | NCI_NATURE; |
reacts with |
JAK1 | REACTOME; |
reacts with |
JAK3 | NCI_NATURE; |
reacts with |
JAK3 | REACTOME; |
reacts with |
LCK | NCI_NATURE; |
reacts with |
PIK3CA | NCI_NATURE; |
reacts with |
PIK3R1 | NCI_NATURE; |
reacts with |
PTK2B | NCI_NATURE; |
reacts with |
PTPN11 | NCI_NATURE; |
reacts with |
PTPN6 | NCI_NATURE; |
reacts with |
SHC1 | NCI_NATURE; |
reacts with |
SHC1 | REACTOME; |
reacts with |
SOS1 | NCI_NATURE; |
reacts with |
SYK | NCI_NATURE; |
reacts with |
SYK | REACTOME; |
state change |
B2M | NCI_NATURE; |
state change |
CD247 | NCI_NATURE; |
state change |
CD3D | NCI_NATURE; |
state change |
CD3E | NCI_NATURE; |
state change |
CD3G | NCI_NATURE; |
state change |
CD8A | NCI_NATURE; |
state change |
CD8B | NCI_NATURE; |
state change |
CISH | NCI_NATURE; |
state change |
HLA-A | NCI_NATURE; |
state change |
IL2 | REACTOME; |
state change |
IL2RA | REACTOME; |
state change |
IL2RB | NCI_NATURE; |
state change |
IL2RB | REACTOME; |
state change |
IL2RG | NCI_NATURE; |
state change |
IL2RG | REACTOME; |
state change |
JAK1 | NCI_NATURE; |
state change |
JAK1 | REACTOME; |
state change |
JAK3 | NCI_NATURE; |
state change |
JAK3 | REACTOME; |
state change |
LCK | NCI_NATURE; |
state change |
RHOA | NCI_NATURE; |
state change |
SOCS1 | NCI_NATURE; |
state change |
SOCS3 | NCI_NATURE; |
state change |
SOCS5 | NCI_NATURE; |
state change |
SYK | REACTOME; |