| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7410 |
Name | VAV2 |
Synonymous | vav 2 guanine nucleotide exchange factor;VAV2;vav 2 guanine nucleotide exchange factor |
Definition | guanine nucleotide exchange factor VAV2|vav 2 oncogene |
Position | 9q34.1 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
SH2B2 | IMID; |
in same component |
SIAH2 | IMID; |
in same component |
TEC | NCI_NATURE; |
in same component |
ZAP70 | IMID; |
interacts with |
ABI1 | MINT; |
interacts with |
CBL | HPRD; |
interacts with |
CBL | MINT; |
interacts with |
CD19 | BIOGRID; |
interacts with |
CD19 | HPRD; |
interacts with |
CD44 | BIOGRID; |
interacts with |
CD44 | HPRD; |
interacts with |
EGFR | BIOGRID; |
interacts with |
EGFR | HPRD; |
interacts with |
EGFR | MINT; |
interacts with |
EPHB2 | HPRD; |
interacts with |
ERBB2 | MINT; |
interacts with |
ERBB3 | MINT; |
interacts with |
NEK3 | HPRD; |
interacts with |
PDGFRB | BIOGRID; |
interacts with |
PRLR | HPRD; |
interacts with |
RAC1 | HPRD; |
interacts with |
RHOA | HPRD; |
interacts with |
SH3BP2 | HPRD; |
interacts with |
SH3BP2 | MINT; |
interacts with |
SOCS1 | BIOGRID; |
interacts with |
SOCS1 | CELL_MAP; |
interacts with |
SOCS1 | HPRD; |
interacts with |
SYK | HPRD; |
interacts with |
SYK | MINT; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
sequential catalysis |
VAV2 | IMID; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
SH2B2 | IMID; |
reacts with |
SIAH2 | IMID; |
reacts with |
TEC | NCI_NATURE; |
reacts with |
VAV2 | IMID; |
reacts with |
VAV2 | NCI_NATURE; |
reacts with |
ZAP70 | IMID; |
state change |
ABL1 | IMID; |
state change |
BLNK | NCI_NATURE; |
state change |
CBLB | IMID; |
state change |
CD19 | NCI_NATURE; |
state change |
CD79A | NCI_NATURE; |
state change |
CD79B | NCI_NATURE; |
state change |
CDC42 | NCI_NATURE; |
state change |
EPOR | NCI_NATURE; |
state change |
EPO | NCI_NATURE; |
state change |
IGF1R | IMID; |
state change |
JAK2 | NCI_NATURE; |
state change |
LCK | IMID; |
state change |
LYN | NCI_NATURE; |
state change |
PIK3CA | NCI_NATURE; |
state change |
PIK3R1 | NCI_NATURE; |
state change |
SRC | IMID; |
state change |
SRC | NCI_NATURE; |
state change |
SYK | NCI_NATURE; |