| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5829 |
Name | PXN |
Synonymous | paxillin;PXN;paxillin |
Definition | - |
Position | 12q24.31 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
ARHGEF7 | NCI_NATURE; |
in same component |
BCAR1 | NCI_NATURE; |
in same component |
CALD1 | REACTOME; |
in same component |
CRK | IMID; |
in same component |
CRK | NCI_NATURE; |
in same component |
CSK | REACTOME; |
in same component |
EPHB1 | NCI_NATURE; |
in same component |
FN1 | NCI_NATURE; |
in same component |
GAB1 | IMID; |
in same component |
GIT1 | NCI_NATURE; |
in same component |
GIT2 | NCI_NATURE; |
in same component |
ILK | NCI_NATURE; |
in same component |
ITGA1 | REACTOME; |
in same component |
ITGA2B | NCI_NATURE; |
in same component |
ITGA4 | NCI_NATURE; |
in same component |
ITGA9 | NCI_NATURE; |
in same component |
ITGB1 | NCI_NATURE; |
in same component |
ITGB3 | NCI_NATURE; |
in same component |
ITGB5 | REACTOME; |
in same component |
LIMS1 | NCI_NATURE; |
in same component |
LMOD1 | REACTOME; |
in same component |
PAK1 | IMID; |
in same component |
PAK1 | NCI_NATURE; |
in same component |
PARVA | NCI_NATURE; |
in same component |
PARVA | REACTOME; |
in same component |
PTK2B | NCI_NATURE; |
in same component |
PTK2 | IMID; |
in same component |
PTK2 | NCI_NATURE; |
in same component |
SORBS1 | REACTOME; |
in same component |
SORBS3 | REACTOME; |
in same component |
SRC | NCI_NATURE; |
in same component |
TLN1 | NCI_NATURE; |
in same component |
TLN1 | REACTOME; |
in same component |
TNC | NCI_NATURE; |
in same component |
VCAM1 | NCI_NATURE; |
in same component |
VCL | REACTOME; |
in same component |
YWHAZ | NCI_NATURE; |
interacts with |
APC | MINT; |
interacts with |
ARHGAP5 | BIOGRID; |
interacts with |
ARHGEF7 | HPRD; |
interacts with |
AR | HPRD; |
interacts with |
ASAP1 | BIOGRID; |
interacts with |
ASAP1 | HPRD; |
interacts with |
ASAP1 | MINT; |
interacts with |
ASAP2 | BIOGRID; |
interacts with |
ASAP2 | HPRD; |
interacts with |
BCAR1 | BIOGRID; |
interacts with |
BCL2 | HPRD; |
interacts with |
CASP3 | HPRD; |
interacts with |
CBL | BIOGRID; |
interacts with |
CEACAM1 | BIOGRID; |
interacts with |
CEACAM1 | HPRD; |
interacts with |
CLTC | HPRD; |
interacts with |
CRKL | BIOGRID; |
interacts with |
CRKL | HPRD; |
interacts with |
CRKL | MINT; |
interacts with |
CRK | BIOGRID; |
interacts with |
CRK | HPRD; |
interacts with |
CRK | MINT; |
interacts with |
CSK | BIOGRID; |
interacts with |
CSK | HPRD; |
interacts with |
CSK | MINT; |
interacts with |
DOK2 | HPRD; |
interacts with |
DVL1 | MINT; |
interacts with |
EPHB1 | HPRD; |
interacts with |
FYN | BIOGRID; |
interacts with |
FYN | HPRD; |
interacts with |
GAB1 | MINT; |
interacts with |
Git1 | BIOGRID; |
interacts with |
GIT1 | BIOGRID; |
interacts with |
GIT1 | MINT; |
interacts with |
GIT2 | BIOGRID; |
interacts with |
GIT2 | HPRD; |
interacts with |
GIT2 | MINT; |
interacts with |
GSK3A | HPRD; |
interacts with |
GSK3B | HPRD; |
interacts with |
GSN | BIOGRID; |
interacts with |
IGF1R | BIOGRID; |
interacts with |
ILK | BIOGRID; |
interacts with |
ILK | HPRD; |
interacts with |
ITGA4 | BIOGRID; |
interacts with |
ITGA4 | HPRD; |
interacts with |
ITGA6 | HPRD; |
interacts with |
ITGA9 | HPRD; |
interacts with |
ITGAV | HPRD; |
interacts with |
ITGB1 | BIOGRID; |
interacts with |
ITGB1 | HPRD; |
interacts with |
ITGB3 | BIOGRID; |
interacts with |
ITGB3 | HPRD; |
interacts with |
ITGB5 | HPRD; |
interacts with |
LCK | BIOGRID; |
interacts with |
LCK | HPRD; |
interacts with |
LIMK1 | HPRD; |
interacts with |
MAPK1 | HPRD; |
interacts with |
MAPK3 | HPRD; |
interacts with |
MAPK8 | HPRD; |
interacts with |
MATK | BIOGRID; |
interacts with |
MATK | HPRD; |
interacts with |
NCK1 | BIOGRID; |
interacts with |
NCK1 | HPRD; |
interacts with |
NEDD9 | BIOGRID; |
interacts with |
NEDD9 | HPRD; |
interacts with |
NF2 | BIOGRID; |
interacts with |
NF2 | HPRD; |
interacts with |
PABPC1 | BIOGRID; |
interacts with |
PABPC1 | HPRD; |
interacts with |
PAK1 | HPRD; |
interacts with |
PARVA | HPRD; |
interacts with |
PDPK1 | HPRD; |
interacts with |
PIK3R1 | BIOGRID; |
interacts with |
PKD1 | HPRD; |
interacts with |
PKLR | BIOGRID; |
interacts with |
PPP2CA | BIOGRID; |
interacts with |
PPP2CA | HPRD; |
interacts with |
PTEN | BIOGRID; |
interacts with |
PTEN | HPRD; |
interacts with |
PTK2B | BIOGRID; |
interacts with |
PTK2B | HPRD; |
interacts with |
Ptk2 | BIOGRID; |
interacts with |
PTK2 | BIOGRID; |
interacts with |
PTK2 | INTACT; |
interacts with |
PTPN11 | HPRD; |
interacts with |
PTPN11 | MINT; |
interacts with |
PTPN12 | BIOGRID; |
interacts with |
PTPN12 | HPRD; |
interacts with |
PTPN1 | HPRD; |
interacts with |
PTPRH | BIOGRID; |
interacts with |
PTPRH | HPRD; |
interacts with |
RAB8B | BIOGRID; |
interacts with |
RAC1 | NCI_NATURE; |
interacts with |
RASA1 | BIOGRID; |
interacts with |
RASA1 | HPRD; |
interacts with |
Reps2 | BIOGRID; |
interacts with |
REPS2 | HPRD; |
interacts with |
RHOA | NCI_NATURE; |
interacts with |
RNF5 | HPRD; |
interacts with |
SDC4 | HPRD; |
interacts with |
SELE | BIOGRID; |
interacts with |
SELE | HPRD; |
interacts with |
SORBS1 | HPRD; |
interacts with |
SRC | BIOGRID; |
interacts with |
SRC | HPRD; |
interacts with |
SRC | MINT; |
interacts with |
SYK | BIOGRID; |
interacts with |
SYK | HPRD; |
interacts with |
TGFB1I1 | BIOGRID; |
interacts with |
TLN1 | BIOGRID; |
interacts with |
TLN1 | HPRD; |
interacts with |
TRIP6 | BIOGRID; |
interacts with |
TRIP6 | HPRD; |
interacts with |
TUBA8 | HPRD; |
interacts with |
TUBG1 | BIOGRID; |
interacts with |
TUBG1 | HPRD; |
interacts with |
TUBG2 | HPRD; |
interacts with |
VCL | BIOGRID; |
interacts with |
VCL | HPRD; |
Metabolic Interaction [Top] | ||
There is no record for PXN | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
ARHGEF7 | NCI_NATURE; |
reacts with |
BCAR1 | NCI_NATURE; |
reacts with |
CALD1 | REACTOME; |
reacts with |
CRK | IMID; |
reacts with |
CRK | NCI_NATURE; |
reacts with |
CSK | REACTOME; |
reacts with |
EPHB1 | NCI_NATURE; |
reacts with |
FN1 | NCI_NATURE; |
reacts with |
GAB1 | IMID; |
reacts with |
GIT1 | NCI_NATURE; |
reacts with |
GIT2 | NCI_NATURE; |
reacts with |
ILK | NCI_NATURE; |
reacts with |
ITGA1 | REACTOME; |
reacts with |
ITGA4 | NCI_NATURE; |
reacts with |
ITGA9 | NCI_NATURE; |
reacts with |
ITGB1 | NCI_NATURE; |
reacts with |
ITGB5 | REACTOME; |
reacts with |
ITGB7 | NCI_NATURE; |
reacts with |
LIMS1 | NCI_NATURE; |
reacts with |
LMOD1 | REACTOME; |
reacts with |
PAK1 | IMID; |
reacts with |
PAK1 | NCI_NATURE; |
reacts with |
PARVA | NCI_NATURE; |
reacts with |
PARVA | REACTOME; |
reacts with |
PTK2B | NCI_NATURE; |
reacts with |
PTK2 | IMID; |
reacts with |
PTK2 | NCI_NATURE; |
reacts with |
PXN | IMID; |
reacts with |
PXN | NCI_NATURE; |
reacts with |
PXN | REACTOME; |
reacts with |
SORBS1 | REACTOME; |
reacts with |
SORBS3 | REACTOME; |
reacts with |
SRC | NCI_NATURE; |
reacts with |
TLN1 | NCI_NATURE; |
reacts with |
TLN1 | REACTOME; |
reacts with |
TNC | NCI_NATURE; |
reacts with |
TRIP6 | NCI_NATURE; |
reacts with |
VCAM1 | NCI_NATURE; |
reacts with |
VCL | REACTOME; |
reacts with |
YWHAZ | NCI_NATURE; |
state change |
CSK | IMID; |
state change |
CXCL12 | NCI_NATURE; |
state change |
CXCR4 | NCI_NATURE; |
state change |
EGF | REACTOME; |
state change |
EGFR | REACTOME; |
state change |
GAB1 | REACTOME; |
state change |
GDNF | NCI_NATURE; |
state change |
GFRA1 | NCI_NATURE; |
state change |
GNG2 | NCI_NATURE; |
state change |
IGF1 | NCI_NATURE; |
state change |
IGF1R | NCI_NATURE; |
state change |
IRS1 | NCI_NATURE; |
state change |
JAK2 | NCI_NATURE; |
state change |
PIK3CA | NCI_NATURE; |
state change |
PIK3R1 | NCI_NATURE; |
state change |
PRKACA | NCI_NATURE; |
state change |
PRKACB | NCI_NATURE; |
state change |
PRKAR1A | NCI_NATURE; |
state change |
PRKAR1B | NCI_NATURE; |
state change |
PTK2B | NCI_NATURE; |
state change |
PTPN11 | CELL_MAP; |
state change |
PTPN11 | IMID; |
state change |
PTPN11 | REACTOME; |
state change |
RAP1B | NCI_NATURE; |
state change |
RGS1 | NCI_NATURE; |
state change |
RPS6KB1 | NCI_NATURE; |
state change |
SRC | NCI_NATURE; |