| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5829 |
Name | PXN |
Synonym | paxillin;PXN;paxillin |
Definition | - |
Position | 12q24.31 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | agrin in postsynaptic differentiation;PID BioCarta;100252 |
Pathway | Cell junction organization;Reactome;REACT:20676 |
Pathway | Signaling events regulated by Ret tyrosine kinase;PID Curated;200058 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | Fc-epsilon receptor I signaling in mast cells;PID Curated;200003 |
Pathway | CXCR4-mediated signaling events;PID Curated;200083 |
Pathway | Signaling events mediated by focal adhesion kinase;PID Curated;200192 |
Pathway | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met);PID Curated;200032 |
Pathway | Bacterial invasion of epithelial cells;KEGG PATHWAY;hsa05100 |
Pathway | VEGF signaling pathway;KEGG PATHWAY;hsa04370 |
Pathway | Signaling by EGFR;Reactome;REACT:9417 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | EPHB forward signaling;PID Curated;200041 |
Pathway | Muscle contraction;Reactome;REACT:17044 |
Pathway | Leukocyte transendothelial migration;KEGG PATHWAY;hsa04670 |
Pathway | cell to cell adhesion signaling;PID BioCarta;100208 |
Pathway | LPA receptor mediated events;PID Curated;200011 |
Pathway | Signaling events mediated by VEGFR1 and VEGFR2;PID Curated;200161 |
Pathway | VEGF signaling pathway;PANTHER;P00056 |
Pathway | ucalpain and friends in cell spread;PID BioCarta;100008 |
Pathway | Regulation of cytoskeletal remodeling and cell spreading by IPP complex components;PID Reactome;500125 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | Integrin signalling pathway;PANTHER;P00034 |
Pathway | IGF1 pathway;PID Curated;200084 |
Pathway | Paxillin-independent events mediated by a4b1 and a4b7;PID Curated;200178 |
Pathway | mTOR signaling pathway;PID Curated;200080 |
Pathway | Angiopoietin receptor Tie2-mediated signaling;PID Curated;200066 |
Pathway | Gab1 signalosome;PID Reactome;500514 |
Pathway | Cell-extracellular matrix interactions;PID Reactome;500123 |
Pathway | erk and pi-3 kinase are necessary for collagen binding in corneal epithelia;PID BioCarta;100184 |
Pathway | Integrins in angiogenesis;PID Curated;200109 |
Pathway | integrin signaling pathway;PID BioCarta;100123 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | Arf6 signaling events;PID Curated;200060 |
Pathway | mcalpain and friends in cell motility;PID BioCarta;100111 |
Pathway | vegf hypoxia and angiogenesis;PID BioCarta;100006 |
Pathway | Localization of the PINCH-ILK-PARVIN complex to focal adhesions;PID Reactome;500124 |
Pathway | Paxillin-dependent events mediated by a4b1;PID Curated;200117 |
Disease | Cancer;FunDO |
External Links | |
Links to Entrez Gene | 5829 |
Links to all GeneRIF Items | 5829 |
Links to iHOP | 5829 |
Sequence Information | |
Nucleotide Sequence | >5829 : length: 6323 GTTCCGGGCCGAGGCTCGCGGCGGAAAAGTTGCGGGGCATAGACGAGCGGCCCCGGGACG GGCAGCTAGCGCGACCCTGAGCCGGCGCCCGTGGTCCGGCCATGGACGACCTCGGTTGCC CTTTTCATGGTTTGCTCATATTCTACCCAGAAAAGACTTAGGAGACTTAGAAGAAGTTAG TACTTTGCATCCTACCTACACTGCTCTCCTTGGAGGAAGACCTTATTCTGGATTTTACAG AGCAAATCAGATCTGATGTTTGTAGCTTCCAATGTGCTATGGAGCTTCCTCCTGCAGAGT GACTTGGGTCTGGAGAGCCTGATATTTGCAACTGATGTCTGCAGCTTCCAGTGTACCTGC TAGCCCTTATAAACCTCACACCAGTACTTTGAGGTCAGAGTTATTCAAGAGCTTACTGAG ACAACAGGCCCTGAGAAGCTAAGCGATTTGCCCTGTGGCATGGATGGTAGAGAGGGGAGC TGGCACTTGAACTCAGGTCTGGCTCGACCTCAGAATGAGTGATCTTGTGTCTCTGTGCCC CAGGACTGCATCCTCTCACCAATACTTCACCAGCCTAGGGATCTGTGCTCCCAAGAGCCT GTTGACATTGTAAACCTGAATCCAATCCATAAACCAAAAGCCCAGGCTTAGAATCACATT GTGGTGGAGCGGGTGTTTGGTGGAGTCCCTGATTCAAAATGTTTGACAAGGAAGCCTGAC CATTTGTCTTCTGTTGGGTGTTTGGAGTCCAAGAGACCTGAGATCAGAGTCCAGCATTGT CACTTCATCCAGCCTTGGCAGTGTGGGATGTGACTCTGCCTCTGAACCGCAGTTATACCA TCTGTGCTGGTGGCGTTGTGAGGATGGCAGGTAACAAAGGTGAAGCTCCTGGCCCCAGTG GGCCTTCAAGGATGGCAGCTGCTCCTGCCCCCTACTGGGGTTGCACTCATTCGTTGCCTG CTCTGGGGAGTCCTATGGGGTTTCTTAGCTGGCCCTGCCCATGGTGGAGAAAGAGGGATC CACCCATTGCTGATTGGGCCCAGAGGAAATGAGGACACTGCGTGAAGCCAAGACAGCAGA CGCCCTGCTGGCGGACTTGGAGTCTACCACCTCCCACATCTCCAAACGGCCTGTGTTCTT GTCGGAGGAGACCCCCTACTCATACCCAACTGGAAACCACACATACCAGGAGATTGCCGT GCCACCCCCCGTCCCCCCACCCCCGTCCAGCGAGGCCCTCAATGGCACAATCCTTGACCC CTTAGACCAGTGGCAGCCCAGCAGCTCCCGATTCATCCACCAGCAGCCTCAGTCCTCATC ACCTGTGTACGGCTCCAGTGCCAAAACTTCCAGTGTCTCCAACCCTCAGGACAGTGTTGG CTCTCCGTGCTCCCGAGTGGGTGAGGAGGAGCACGTCTACAGCTTCCCCAACAAGCAGAA ATCAGCTGAGCCTTCACCCACCGTAATGAGCACGTCCCTGGGCAGCAACCTTTCTGAACT CGACCGCCTGCTGCTGGAACTGAACGCTGTACAGCATAACCCGCCAGGCTTCCCTGCAGA TGAGGCCAACTCAAGCCCCCCGCTTCCTGGGGCCCTGAGCCCCCTCTATGGTGTCCCAGA GACTAACAGCCCCTTGGGAGGCAAAGCTGGGCCCCTGACGAAAGAGAAGCCTAAGCGGAA TGGGGGCCGGGGCCTGGAGGACGTGCGGCCCAGTGTGGAGAGTCTCTTGGATGAACTGGA GAGCTCCGTGCCCAGCCCCGTCCCTGCCATCACTGTGAACCAGGGCGAGATGAGCAGCCC GCAGCGCGTCACCTCCACCCAACAGCAGACACGCATCTCGGCCTCCTCTGCCACCAGGGA GCTGGACGAGCTGATGGCTTCGCTGTCGGATTTCAAGACCAGCTCCTCCACTGTGGCTCT GAGTGCCCCGGGGCTGTCCAGCTCTGCTCCGTCCTCATACTGCTCCCTTCCTCCTTCTCC TCCTCCCATGCCATCTGTATTTCTGCCACCCACCACTATACCCTCCCCTCGAGGCCAGGG CCACACTCCGGAGTTCCCTTGTACTGAGCAGAGTGGACGAGGCCTTCTACCTCCTGTAGC CCCCAGCTGGCTTGATTTGGCTGGTCTTGGGGTGATGCCTGACACCTTCAACTCAAGGTC TCCCTCTGTGGAGGGTTCTCTGTGGGCAGTGGGCACAGAGAGTCAGGGTCGAGATTGGAG GCACCTGCCGACCATCACAAGTGAGCTCTCTGGGGCTCCCCGCTGCCACACTGTACCCTG TGCTGGGAGCACAGCTCTCCAAGAGCCTGGGGAGCCCCAGGGGCCACCAGCCAGCCCTTC GTGCCCAGAGGAGGCCTTGGCTGCCACATGGGAGCAGCCATGGGCTTCGGAGGTATTCGG GCCTGAGAGAATGCCCCCCTCTGGAGCTGCTCGAAGCTTCCAAGAAGTAACAGAGCCAGC TGTAGTGGCAGTGGACCGGCAGGCCATCTTCCCAGATACCTGGACTCTCACGGAGGAACA TGGCCTACAGCAGGAGAGGCCAAGGCCAGAGCCAGGGAGGCTGGGAAGCAGCTCCCCTGC CTCAGTTACCACGGAGCAGCTAGGTGCAAAGATGACCGAGAGGGGAAGTGTGGCCAGGCC AACCCAGGGACCTGAAACCCCAAGGAGCCCAGAGGGCACCACGGAAGCTGCCACCCAGGA CGGGAAGGAACAGCCAGAGCTTCCATGTGCCATGGCCATGGGCACACCCAGCACCACGGA GAGGATTTCCACCTCTGGCCAGATCCGATCTGTGATCAGGAGGAGCTGGGAGTCTGGCCA CGCACACCCCATGTCCCGGGAGCCCTCCCCTCGCCGCCGGCTGGACCCTGCCACCTTGAG CAGGACCCCATCCCAGGAACAGCTCATCGCGGAGCTGCAGGGGCGGCTGGGCATCCAGCC TGAGGCAGAGGAGCCGGCGGAGGCGGCGGGGCCCTCTGCCCAGGACTGGCTGACCGAGGG CGTCATCATCACTGTGCAGCCACGTGGGAAGCGGGCCGGGGGGCAGCTCGTAGAGAAGGT TGTCTTCCCTCCTGGCTCTCCCATTCCCCTGAGAAGAACCATCTCTGTCCTGGCTTCTCC TTCTGTCCCTTTGCTCCAGCATCGCACAGACGCCGCGGCCAGCAGCTCTTCTCCCCTGCC CAGCCTGCTCGCCTCCTCCCCCCTGGGGCCCTCAGCTTATACCTGTGGTTCTTCTGGGGT CCAGAGTGCAGGGGAAGAGCCCCATGATGAGGGGGTGCAGGGCCCTGCCCTTCCCATTCC TGCACCCCACACCATGAGGTCCGTGGGCTGCCAGACTGATGAGGACCCGCTCTTCCCCCC GATGCAGATCCAGGGCCTGGAGCAAAGAGCGGATGGGGAGCGGTGCTGGGCGGCCGGCTG GCCTCGGGACGGCGGGCGGAGCAGCCCCGGAGGGCAGGACGAGGGAGGGGGCTCCTGGCC CCTGGAGGAGGTTGTACTTCTTGTCTCCATCAGCTCATCTGTCCAGGAGGGAGAAAAGTA CCCCCATCCCTGTGCTGCCAGACACCGTACCCCGAGCCTCAGGAGTCCTGACCAGCCCCC TCCGTGTCCACAGTTCATGGCCCAGGGGAAGACAGGGAGCAGCTCACCCCCTGGGGGGCC CCCGAAGCCCGGGAGCCAGCTGGACAGCATGCTGGGGAGCCTGCAGTCTGACCTGAACAA GCTGGGGGTCGCCACAGTCGCCAAAGGAGTCTGCGGGGCCTGCAAGAAGCCCATCGCCGG GCAGGTTGTGACCGCCATGGGGAAGACGTGGCACCCCGAGCACTTCGTCTGCACCCACTG CCAGGAGGAGATCGGATCCCGGAACTTCTTCGAGCGGGATGGACAGCCCTACTGTGAAAA GGACTACCACAACCTCTTCTCCCCGCGCTGCTACTACTGCAACGGCCCCATCCTGGATAA AGTGGTGACAGCCCTTGACCGGACGTGGCACCCTGAACACTTCTTCTGTGCACAGTGTGG AGCCTTCTTTGGTCCCGAAGGGTTCCACGAGAAGGACGGCAAGGCCTACTGTCGCAAGGA CTACTTCGACATGTTCGCACCCAAGTGTGGCGGCTGCGCCCGGGCCATCCTGGAGAACTA TATCTCAGCCCTCAACACGCTGTGGCATCCTGAGTGCTTTGTGTGCCGGGAATGCTTCAC GCCATTCGTGAACGGCAGCTTCTTCGAGCACGACGGGCAGCCCTACTGTGAGGTGCACTA CCACGAGCGGCGCGGCTCGCTGTGTTCTGGCTGCCAGAAGCCCATCACCGGCCGCTGCAT CACCGCCATGGCCAAGAAGTTCCACCCCGAGCACTTCGTCTGTGCCTTCTGCCTCAAGCA GCTCAACAAGGGCACCTTCAAGGAGCAGAACGACAAGCCTTACTGTCAGAACTGCTTCCT CAAGCTCTTCTGCTAGGTGCCCTGCCCCTGTCTCTGCCCCCCTTCCCCAGCCAGCATCCC CAACTGCGACTGTGACCTAGAGACTTCACCCGGGGGTGAAGGGGTAAACCCGACTGAAAC TGGAACCCTTGTCCTCCGCTGGTGCGGGATGGACAGAGGGCCGTGAGGGGTCCCCCTGCT TGTCTTCACCCCTGCCAGAGCCTCTGGGCCCCCTCCTCCCTCCTGTAGCTCTCCCTAGGC TGCCCACTCTCCATCCTCCCCAGGGGTAGAGGCTGGGGGCTCCACCCCAGCCCATGTACG TCCCCACGAACTGGCCTGGCCAGCACCCCACACTGGAGCCATCTCTTCCTCATATTTCAG CAGTGCAGCCGGGGGGCAGGGAAGGGCAGGCAGGGTCTGTTGGGGTCTCTTTTTATCCTT ATTCCTCCCCCGACCTAATTGTCTTTGTTCTGTGATTATTGGGGGACACCCGGCTCCCTC CAGACAATGCCAGCATAAATCCATCCATCCAAAGGCAGAGAACCAAAGGGGCCATGGAAG GTTCTCTGTGCTCCTCCTACCCTTCCAGTGCCCTAGGCCTGGCGACTGCCCCTGCCTTTT AGACCCGCCCTCCCCTTTTATACCTGCTCTTGTTCTACTGAGAAAAGCCTCTCCAGCAAT AATGTTTTCTAGTCACTTCCTCCGTCTCCGGGACGGCGTGCCTGGACACTGTACCGACTT TGATAGATTTCTACACTGAGGTTTGAATTCATATCGCCTGAGTTGCTTTTACTTCTCTAT ACAAAATGATTTTGAAGAGATTTTAAAGACGTTCCCTTTTGTATTCTCTTCCTCATCCAC CGCCACTGGGCCTGTCACTGATGGTGGCTCTGGTGTGAAGTTTGCTTTGTACTGAGGGTT GGGGTGGGGAAGCAATTTGTATTTTATTGTTTCTTAGCACAAGCAGGTGAACTGGGAGCA GCTCTGTGACTCCCCCTCTTTCACTTCATAGCTCACCAGGACTGTTTTATAAACTGCTGT ATTTGGAAACCCCTTCTTTACTTCCCAGGCCAGCAAGCTCTTCACTGAAACTGGTTGAAG GGTGTTGCACCCTTTTGGGCCTAGAATTCTGAACTTTATCTGTTCTGTTTCTGTGGGAGG AGAAGGGGAAGTATGTTTTGGGGGGCTGCTTCCTGTCTGAGTAAGCCCTCAGGAGCCTCT GCTCCCCTGTGAACCCACTGAACCTTCTGAGCCCCCACTGCTTCTATGGGGCTCTCTCTT CTGCCTTCTCAGGAAAGCTGGTGTCTGATTTTGGCCATCAGGACTCTGACGTCTCTTTGG TCTTGTTGATTTCCTCTGGGCATATCCCTTCCCCAGATCTGCTCCTCCCCTTTCACAGGT GGGATCGGCACTCAGGGGGTCTGGAAAGAAGGTCATAAGGGAGCATGATAGGATTTGGGG CAGAGGGACAGGCTCCTCTGGGGAAACCCCCCAGAGCTCTTTACCAAGGATGAAAGAGGA GCCAGGCCTTGGGCTCCTGATGAGGAGAAAGGGGCCCCACCGGGGTCTAATGGTGACAGT CCAAACCACTCCACTGGCCTCCTGGCAGAAGCCGAGTGTGCTGGGGTCTCCGAAGAGGGT CCCTCCTTTTTGGGGGAAGGTCAGCCCAGCCCCTCCAAAGGTCTGATGTCTCCACTTTCA CCCGCAGGCCTTACCGCTCTGTTTATAGTGACCCACCCTAGATCTTCCCCAAGAGGGACT GGGGTTTCTGGGGTCCATTCTCTGAGTCAGTGGTTATTTGAAAATTTGATTTTGATTTTA TTTTTTCTCTGTAAACTTCCAAGCTGGCTTTTCCCATTTCAATTCCTGTGATTTATGCCA ATAAAGTTTGCCCATGATTTTCA |
Protein Sequence | >5829 : length: 1135 MRTLREAKTADALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPS SEALNGTILDPLDQWQPSSSRFIHQQPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEE EHVYSFPNKQKSAEPSPTVMSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLP GALSPLYGVPETNSPLGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPA ITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKTSSSTVALSAPGLSSSA PSSYCSLPPSPPPMPSVFLPPTTIPSPRGQGHTPEFPCTEQSGRGLLPPVAPSWLDLAGL GVMPDTFNSRSPSVEGSLWAVGTESQGRDWRHLPTITSELSGAPRCHTVPCAGSTALQEP GEPQGPPASPSCPEEALAATWEQPWASEVFGPERMPPSGAARSFQEVTEPAVVAVDRQAI FPDTWTLTEEHGLQQERPRPEPGRLGSSSPASVTTEQLGAKMTERGSVARPTQGPETPRS PEGTTEAATQDGKEQPELPCAMAMGTPSTTERISTSGQIRSVIRRSWESGHAHPMSREPS PRRRLDPATLSRTPSQEQLIAELQGRLGIQPEAEEPAEAAGPSAQDWLTEGVIITVQPRG KRAGGQLVEKVVFPPGSPIPLRRTISVLASPSVPLLQHRTDAAASSSSPLPSLLASSPLG PSAYTCGSSGVQSAGEEPHDEGVQGPALPIPAPHTMRSVGCQTDEDPLFPPMQIQGLEQR ADGERCWAAGWPRDGGRSSPGGQDEGGGSWPLEEVVLLVSISSSVQEGEKYPHPCAARHR TPSLRSPDQPPPCPQFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKG VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC GGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCS GCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC |