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Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

3689

Name

ITGB2

Synonymous

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit);ITGB2;integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

Definition

cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor)|complement receptor C3 beta-subunit|integrin beta chain, beta 2|integrin beta-2|leukocyte cell adhesion molecule CD18|leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C

Position

21q22.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 AGERNCI_NATURE;

in same component

 AMICA1REACTOME;

in same component

 APOBNCI_NATURE;

in same component

 C3NCI_NATURE;

in same component

 CD40LGNCI_NATURE;

in same component

 CTGFNCI_NATURE;

in same component

 CYR61NCI_NATURE;

in same component

 F10NCI_NATURE;

in same component

 F11RNCI_NATURE;

in same component

 F11RREACTOME;

in same component

 FCGR2ANCI_NATURE;

in same component

 FGANCI_NATURE;

in same component

 FGAREACTOME;

in same component

 FGBNCI_NATURE;

in same component

 FGBREACTOME;

in same component

 FGGNCI_NATURE;

in same component

 FGGREACTOME;

in same component

 GP1BANCI_NATURE;

in same component

 HCKNCI_NATURE;

in same component

 HMGB1NCI_NATURE;

in same component

 ICAM1NCI_NATURE;

in same component

 ICAM2NCI_NATURE;

in same component

 ICAM3NCI_NATURE;

in same component

 ICAM4NCI_NATURE;

in same component

 ITGADNCI_NATURE;

in same component

 ITGADREACTOME;

in same component

 ITGALNCI_NATURE;

in same component

 ITGALREACTOME;

in same component

 ITGAMNCI_NATURE;

in same component

 ITGAMREACTOME;

in same component

 ITGAXNCI_NATURE;

in same component

 ITGAXREACTOME;

in same component

 JAM3NCI_NATURE;

in same component

 JAM3REACTOME;

in same component

 KNG1NCI_NATURE;

in same component

 LPANCI_NATURE;

in same component

 LRP1NCI_NATURE;

in same component

 MMP2NCI_NATURE;

in same component

 MMP9NCI_NATURE;

in same component

 PLATNCI_NATURE;

in same component

 PLAUNCI_NATURE;

in same component

 PLAURNCI_NATURE;

in same component

 PLGNCI_NATURE;

in same component

 PROCNCI_NATURE;

in same component

 SELPNCI_NATURE;

in same component

 SELPLGNCI_NATURE;

in same component

 SPON2NCI_NATURE;

in same component

 TGFBINCI_NATURE;

in same component

 THY1NCI_NATURE;

in same component

 TLN1NCI_NATURE;

in same component

 VCAM1NCI_NATURE;

interacts with

 ABL1MINT;

interacts with

 AKT1NCI_NATURE;

interacts with

 ANKS1BMINT;

interacts with

 CD14HPRD;

interacts with

 CD226BIOGRID;

interacts with

 CD226HPRD;

interacts with

 CD63HPRD;

interacts with

 CD82HPRD;

interacts with

 COPS3HPRD;

interacts with

 COPS3MINT;

interacts with

 CYTH1BIOGRID;

interacts with

 CYTH1HPRD;

interacts with

 CYTH1MINT;

interacts with

 CYTH2HPRD;

interacts with

 DAB1HPRD;

interacts with

 Dab1MINT;

interacts with

 DOK1HPRD;

interacts with

 Dok1MINT;

interacts with

 EPS8MINT;

interacts with

 ESM1HPRD;

interacts with

 FCER2HPRD;

interacts with

 FHL2BIOGRID;

interacts with

 FHL2HPRD;

interacts with

 FUT4HPRD;

interacts with

 GULP1MINT;

interacts with

 HPHPRD;

interacts with

 ICAM1BIOGRID;

interacts with

 ICAM1HPRD;

interacts with

 ICAM2HPRD;

interacts with

 ICAM3HPRD;

interacts with

 ICAM4HPRD;

interacts with

 ICAM5HPRD;

interacts with

 ILKHPRD;

interacts with

 Irs1MINT;

interacts with

 ITGADBIOGRID;

interacts with

 ITGALBIOGRID;

interacts with

 ITGAMHPRD;

interacts with

 ITGAXHPRD;

interacts with

 KNG1BIOGRID;

interacts with

 MAPK8IP1MINT;

interacts with

 NUMBHPRD;

interacts with

 NumbMINT;

interacts with

 P2rx7BIOGRID;

interacts with

 PLAURBIOGRID;

interacts with

 PRKCAHPRD;

interacts with

 PRKCBHPRD;

interacts with

 PRKCDHPRD;

interacts with

 PRKCHHPRD;

interacts with

 PRKCZNCI_NATURE;

interacts with

 PRTN3HPRD;

interacts with

 PTK2BBIOGRID;

interacts with

 PTK2BHPRD;

interacts with

 RABGAP1MINT;

interacts with

 RANBP9HPRD;

interacts with

 RANBP9MINT;

interacts with

 RDXHPRD;

interacts with

 RDXMINT;

interacts with

 Shc1MINT;

interacts with

 SYKBIOGRID;

interacts with

 SYKHPRD;

interacts with

 TLN1HPRD;

interacts with

 Tln1MINT;

interacts with

 TLN2MINT;

interacts with

 VAV1MINT;

interacts with

 VNN2BIOGRID;

interacts with

 VNN2HPRD;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 ARNTNCI_NATURE;

metabolic catalysis

 HIF1ANCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 AGERNCI_NATURE;

reacts with

 AMICA1REACTOME;

reacts with

 APOBNCI_NATURE;

reacts with

 C3NCI_NATURE;

reacts with

 CD40LGNCI_NATURE;

reacts with

 CTGFNCI_NATURE;

reacts with

 CYR61NCI_NATURE;

reacts with

 F10NCI_NATURE;

reacts with

 F11RNCI_NATURE;

reacts with

 F11RREACTOME;

reacts with

 FCGR2ANCI_NATURE;

reacts with

 FGANCI_NATURE;

reacts with

 FGAREACTOME;

reacts with

 FGBNCI_NATURE;

reacts with

 FGBREACTOME;

reacts with

 FGGNCI_NATURE;

reacts with

 FGGREACTOME;

reacts with

 GP1BANCI_NATURE;

reacts with

 HCKNCI_NATURE;

reacts with

 HMGB1NCI_NATURE;

reacts with

 ICAM1NCI_NATURE;

reacts with

 ICAM2NCI_NATURE;

reacts with

 ICAM3NCI_NATURE;

reacts with

 ICAM4NCI_NATURE;

reacts with

 ITGADNCI_NATURE;

reacts with

 ITGADREACTOME;

reacts with

 ITGALNCI_NATURE;

reacts with

 ITGALREACTOME;

reacts with

 ITGAMNCI_NATURE;

reacts with

 ITGAMREACTOME;

reacts with

 ITGAXNCI_NATURE;

reacts with

 ITGAXREACTOME;

reacts with

 ITGB2NCI_NATURE;

reacts with

 ITGB2REACTOME;

reacts with

 JAM2NCI_NATURE;

reacts with

 JAM3NCI_NATURE;

reacts with

 JAM3REACTOME;

reacts with

 KNG1NCI_NATURE;

reacts with

 LPANCI_NATURE;

reacts with

 LRP1NCI_NATURE;

reacts with

 MMP2NCI_NATURE;

reacts with

 MMP9NCI_NATURE;

reacts with

 PLATNCI_NATURE;

reacts with

 PLAUNCI_NATURE;

reacts with

 PLAURNCI_NATURE;

reacts with

 PLGNCI_NATURE;

reacts with

 PROCNCI_NATURE;

reacts with

 SELPNCI_NATURE;

reacts with

 SELPLGNCI_NATURE;

reacts with

 SPON2NCI_NATURE;

reacts with

 TGFBINCI_NATURE;

reacts with

 THY1NCI_NATURE;

reacts with

 TLN1NCI_NATURE;

reacts with

 VCAM1NCI_NATURE;

state change

 MST1NCI_NATURE;

state change

 MST1RNCI_NATURE;