| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7465 |
Name | WEE1 |
Synonym | WEE1A|WEE1hu;WEE1 G2 checkpoint kinase;WEE1;WEE1 G2 checkpoint kinase |
Definition | WEE1 homolog|WEE1+ homolog|wee1-like protein kinase|wee1A kinase |
Position | 11p15.4 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | G2/M Transition;PID Reactome;500378 |
Pathway | G2/M DNA replication checkpoint;PID Reactome;500939 |
Pathway | cell cycle: g2/m checkpoint;PID BioCarta;100159 |
Pathway | Cyclin E associated events during G1/S transition;PID Reactome;500877 |
Pathway | Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex;PID Reactome;500318 |
Pathway | Cell Cycle Checkpoints;Reactome;REACT:1538 |
Pathway | rb tumor suppressor/checkpoint signaling in response to dna damage;PID BioCarta;100046 |
Pathway | Cyclin A:Cdk2-associated events at S phase entry;PID Reactome;500375 |
Pathway | Polo-like kinase mediated events;PID Reactome;500379 |
Pathway | cdc25 and chk1 regulatory pathway in response to dna damage;PID BioCarta;100212 |
Pathway | Cell cycle;KEGG PATHWAY;hsa04110 |
Pathway | Cyclin A/B1 associated events during G2/M transition;PID Reactome;500991 |
Pathway | PLK1 signaling events;PID Curated;200087 |
Pathway | Cell Cycle, Mitotic;Reactome;REACT:152 |
Disease | Chronic fatigue syndrome;FunDO |
Disease | Liver cancer;FunDO |
External Links | |
Links to Entrez Gene | 7465 |
Links to all GeneRIF Items | 7465 |
Links to iHOP | 7465 |
Sequence Information | |
Nucleotide Sequence | >7465 : length: 3374 CTGAGACTGGACCTGAGGAGACCTCAGCCTCGGTGCTCGGGCCGCCCCGCCTCTGCCGGA AAGTCCGCGCCGCCGCTGCCGCCACCGTCCGCAGCCCGAGCGCCCCGGAGCCGCAGGCCG CCGCCGCGCAGAGACGCCGCGGCTGCGACTAGGCGCGCCCAGCCGCACGTGGCGGACCCG CCCCCAGGCCCGCAGTGTCCTGGACCCCGCAGGCCTCCGCTCTCCTGTCCTCGGCCCCGT CCCCAGGGCCGCGATGAGCTTCCTGAGCCGACAGCAGCCGCCGCCACCCCGCCGCGCCGG GGCGGCCTGCACCTTGCGGCAGAAGCTGATCTTCTCGCCCTGCAGCGACTGTGAGGAGGA GGAAGAAGAGGAGGAGGAGGAGGGCAGCGGCCACAGCACCGGGGAGGACTCGGCCTTTCA AGAGCCCGACTCGCCGCTGCCGCCCGCGCGGAGCCCCACGGAGCCCGGGCCCGAGCGCCG CCGCTCGCCCGGGCCGGCCCCCGGCAGCCCCGGCGAGCTGGAGGAGGACCTGTTGCTGCC CGGCGCCTGCCCGGGCGCGGACGAGGCGGGCGGTGGGGCGGAGGGCGACTCGTGGGAGGA GGAGGGCTTCGGCTCCTCGTCGCCGGTCAAGTCGCCGGCGGCCCCCTACTTCCTGGGTAG CTCTTTCTCGCCGGTGCGCTGCGGCGGCCCAGGAGATGCGTCGCCGCGGGGTTGCGGGGC GCGCCGGGCGGGCGAAGGCCGCCGCTCGCCGCGGCCGGACCACCCGGGCACCCCGCCACA CAAGACCTTCCGCAAGCTGCGACTCTTCGACACCCCGCACACGCCCAAGAGTTTGCTCTC CAAAGCTCGGGGAATTGATTCCAGCTCTGTTAAACTCCGGGGTAGTTCTCTCTTCATGGA TACAGAAAAATCAGGAAAAAGGGAATTTGATGTGCGACAGACTCCTCAAGTGAATATTAA TCCTTTTACTCCGGATTCTTTGTTGCTTCATTCCTCAGGACAGTGTCGTCGTAGAAAGAG AACGTATTGGAATGATTCCTGTGGTGAAGACATGGAAGCCAGTGATTATGAGCTTGAAGA TGAAACAAGACCTGCTAAGAGAATTACAATTACTGAAAGCAATATGAAGTCCCGGTATAC AACAGAATTTCATGAGCTAGAGAAAATCGGCTCTGGAGAATTTGGTTCTGTATTTAAGTG TGTGAAGAGGCTGGATGGATGCATTTATGCCATTAAGCGATCAAAAAAGCCATTGGCGGG CTCTGTTGATGAGCAGAACGCTTTGAGAGAAGTATATGCTCATGCAGTGCTTGGACAGCA TTCTCATGTAGTTCGATATTTCTCTGCGTGGGCAGAAGATGATCATATGCTTATACAGAA TGAATATTGTAATGGTGGAAGTTTAGCTGATGCTATAAGTGAAAACTACAGAATCATGAG TTACTTTAAAGAAGCAGAGTTGAAGGATCTCCTTTTGCAAGTTGGCCGAGGCTTGAGGTA TATTCATTCAATGTCTTTGGTTCACATGGATATAAAACCTAGTAATATTTTCATATCTCG AACCTCAATCCCAAATGCTGCCTCTGAAGAAGGAGACGAAGATGATTGGGCATCCAACAA AGTTATGTTTAAAATAGGTGATCTTGGGCATGTAACAAGGATCTCCAGTCCACAAGTTGA AGAGGGCGATAGTCGTTTTCTTGCAAATGAAGTTTTACAGGAGAATTATACCCATCTACC AAAAGCAGATATTTTTGCGCTTGCCCTCACAGTGGTATGTGCTGCTGGTGCTGAACCTCT TCCGAGAAATGGAGATCAATGGCATGAAATCAGACAGGGTAGATTACCTCGGATACCACA AGTGCTTTCCCAAGAATTTACAGAGTTGCTAAAAGTTATGATTCATCCAGATCCAGAGAG AAGACCTTCAGCAATGGCACTGGTAAAGCATTCAGTATTGCTGTCCGCTTCTAGAAAGAG TGCAGAACAATTACGAATAGAATTGAATGCCGAAAAGTTCAAAAATTCACTTTTACAAAA AGAACTCAAGAAAGCACAGATGGCAAAAGCTGCAGCTGAGGAAAGAGCACTCTTCACTGA CCGGATGGCCACTAGGTCCACCACCCAGAGTAATAGAACATCTCGACTTATTGGAAAGAA AATGAACCGCTCTGTCAGCCTTACTATATACTGAGCTACTCCTTTCCCACCTCCCCCTGA ACACTGTGACAAGAGGAAGCTAGGTTGAAATCACTGATAGAATCCAGTTTGCAATTACTT TCTCGATTGGTGTCAGTAGTTTTACTGATTAGGACTTTTATTGTGAATTACAGTTGAAAG CTGTATTTTGATGATTGCTATGTCAGGCTTTCATCTAATCTTACCAGTCTGTCTTCTGTA GGATGTGTCACTGTTGGATGTTACACCAGCCTTTCCAGGGTTAACCACTGTGGTGGTGTG CTGCTTATAGTTTGCTGTTGCATTGTAATAAAAGGTGTCTTTCCCTGTAGTGACCTGTAA AAAGTACTCAAGGGCTTTATTACAGACATACCCTCCCTTTGAAAAGGGACATGCTAAAAG ACTCATTACTACTCAGCCTTCAATGTACCTGTGTGTCCATCTTATATTTCTTTTTTTTTT AATTGTGAATTAGACTTGTATATCCCACTGGGAGCACTTTGTAGGCATTGCATGAACCAT GGGATGATGATTCTGTGGAGGTATTGCCTTGTGAATTTGCTGCTATTTTAGTTTTGTCTT TGCTGTAAACTTGTAGCATTAAACAATCATTGTTGTTAATAGGTCTTCTTTTTGAAACAA TTATGTGAAATGTATAGCTGCTTTTGATGAAAAGCAGCTATTTGCCTTTTTTTTTTTTTC CTTTGAACTTTGAAGCTAGTGCATTGGAAAAATGCACCCTTTCCCTCCTTTGGAATGCTG TATTAATGTAGTATAATAATTACTGGTTTTGTAACTTGTTCTGGTAATGTCCTTCCCGGA CTCTTTTTAAATGTCTCCCCCTAAGTTTTATACTTGATTGTATTATTAGTCTGTTTTTAA ATGTTTTGCCCGGTTTTTCTCTTCAATATTTGTGTATATAAACCGATCTTCGTGATACTG TACATAGCTGTTTGAAATGCCAGAATGACTTCTGACATTCCAAGTTTTTCACAAAATATA TTTTATCTGTGATTAGCCATTTGACTAATAATACTGGCTAACAGATGTTGAAAAAAATTG TCTGTTTGTTTTCTCATTAATTTTGGTCTAAAACATGTTTGCACTTGTCTTTGACTTGTG TTTTATTAACATTGATTGGCATATTAAAAGTCACTCTGAGCTTACCTTAATTGTCTAAAA AAAAAAAAAAAAAA |
Protein Sequence | >7465 : length: 647 MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDS PLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFG SSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFR KLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTP DSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFH ELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVV RYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSM SLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDS RFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQ EFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKK AQMAKAAAEERALFTDRMATRSTTQNDPNFQCKFKGLWSKEKYLCMP |