| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5590 |
Name | PRKCZ |
Synonym | PKC-ZETA|PKC2;protein kinase C, zeta;PRKCZ;protein kinase C, zeta |
Definition | nPKC-zeta|protein kinase C zeta type |
Position | 1p36.33-p36.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway;PANTHER;P00027 |
Pathway | p75(NTR)-mediated signaling;PID Curated;200103 |
Pathway | ErbB1 downstream signaling;PID Curated;200113 |
Pathway | 5HT2 type receptor mediated signaling pathway;PANTHER;P04374 |
Pathway | RhoA signaling pathway;PID Curated;200007 |
Pathway | CXCR4-mediated signaling events;PID Curated;200083 |
Pathway | GPVI-mediated activation cascade;PID Reactome;500294 |
Pathway | Thyrotropin-releasing hormone receptor signaling pathway;PANTHER;P04394 |
Pathway | FGF signaling pathway;PANTHER;P00021 |
Pathway | TNF receptor signaling pathway;PID Curated;200086 |
Pathway | Endothelin signaling pathway;PANTHER;P00019 |
Pathway | Neurotrophic factor-mediated Trk receptor signaling;PID Curated;200128 |
Pathway | EGF receptor signaling pathway;PANTHER;P00018 |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | CDC42 signaling events;PID Curated;200057 |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | Insulin Pathway;PID Curated;200012 |
Pathway | Histamine H1 receptor mediated signaling pathway;PANTHER;P04385 |
Pathway | VEGF signaling pathway;PANTHER;P00056 |
Pathway | phosphoinositides and their downstream targets;PID BioCarta;100059 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Thromboxane A2 receptor signaling;PID Curated;200069 |
Pathway | Noncanonical Wnt signaling pathway;PID Curated;200016 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | IGF1 pathway;PID Curated;200084 |
Pathway | IL1-mediated signaling events;PID Curated;200075 |
Pathway | Alzheimer disease-amyloid secretase pathway;PANTHER;P00003 |
Pathway | Oxytocin receptor mediated signaling pathway;PANTHER;P04391 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Role of Calcineurin-dependent NFAT signaling in lymphocytes;PID Curated;200076 |
Pathway | Insulin-mediated glucose transport;PID Curated;200168 |
Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway;PANTHER;P00042 |
Pathway | Ceramide signaling pathway;PID Curated;200100 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | Tight junction;KEGG PATHWAY;hsa04530 |
Pathway | IL2 signaling events mediated by PI3K;PID Curated;200099 |
Pathway | Type II diabetes mellitus;KEGG PATHWAY;hsa04930 |
Pathway | amb2 Integrin signaling;PID Curated;200108 |
Disease | diabetes, type 2;GAD |
Disease | METABOLIC;GAD |
External Links | |
Links to Entrez Gene | 5590 |
Links to all GeneRIF Items | 5590 |
Links to iHOP | 5590 |
Sequence Information | |
Nucleotide Sequence | >5590 : length: 3125 CGCGCGCCGCCGGAGTTCCGCGGAGTTGACCGGGTCGGCGCCGTCGGTCCTGAGCGCTGC CTTCCGCGTTCCGCCGCGGCCCCACCTGGAGCCCCCGCCCCGCGCCATGGCCGGAGCTCC CGGGGCGCAGCGCTGACGGCGGCGGGGGGAGCGCGCCATGCCCAGCAGGACCGGCCCCAA GATGGAAGGGAGCGGCGGCCGCGTCCGCCTCAAGGCGCATTACGGGGGGGACATCTTCAT CACCAGCGTGGACGCCGCCACGACCTTCGAGGAGCTCTGTGAGGAAGTGAGAGACATGTG TCGTCTGCACCAGCAGCACCCGCTCACCCTCAAGTGGGTGGACAGCGAAGGTGACCCTTG CACGGTGTCCTCCCAGATGGAGCTGGAAGAGGCTTTCCGCCTGGCCCGTCAGTGCAGGGA TGAAGGCCTCATCATTCATGTTTTCCCGAGCACCCCTGAGCAGCCTGGCCTGCCATGTCC GGGAGAAGACAAATCTATCTACCGCCGGGGAGCCAGAAGATGGAGGAAGCTGTACCGTGC CAACGGCCACCTCTTCCAAGCCAAGCGCTTTAACAGGAGAGCGTACTGCGGTCAGTGCAG CGAGAGGATATGGGGCCTCGCGAGGCAAGGCTACAGGTGCATCAACTGCAAACTGCTGGT CCATAAGCGCTGCCACGGCCTCGTCCCGCTGACCTGCAGGAAGCATATGGATTCTGTCAT GCCTTCCCAAGAGCCTCCAGTAGACGACAAGAACGAGGACGCCGACCTTCCTTCCGAGGA GACAGATGGAATTGCTTACATTTCCTCATCCCGGAAGCATGACAGCATTAAAGACGACTC GGAGGACCTTAAGCCAGTTATCGATGGGATGGATGGAATCAAAATCTCTCAGGGGCTTGG GCTGCAGGACTTTGACCTAATCAGAGTCATCGGGCGCGGGAGCTACGCCAAGGTTCTCCT GGTGCGGTTGAAGAAGAATGACCAAATTTACGCCATGAAAGTGGTGAAGAAAGAGCTGGT GCATGATGACGAGGATATTGACTGGGTACAGACAGAGAAGCACGTGTTTGAGCAGGCATC CAGCAACCCCTTCCTGGTCGGATTACACTCCTGCTTCCAGACGACAAGTCGGTTGTTCCT GGTCATTGAGTACGTCAACGGCGGGGACCTGATGTTCCACATGCAGAGGCAGAGGAAGCT CCCTGAGGAGCACGCCAGGTTCTACGCGGCCGAGATCTGCATCGCCCTCAACTTCCTGCA CGAGAGGGGGATCATCTACAGGGACCTGAAGCTGGACAACGTCCTCCTGGATGCGGACGG GCACATCAAGCTCACAGACTACGGCATGTGCAAGGAAGGCCTGGGCCCTGGTGACACAAC GAGCACTTTCTGCGGAACCCCGAATTACATCGCCCCCGAAATCCTGCGGGGAGAGGAGTA CGGGTTCAGCGTGGACTGGTGGGCGCTGGGAGTCCTCATGTTTGAGATGATGGCCGGGCG CTCCCCGTTCGACATCATCACCGACAACCCGGACATGAACACAGAGGACTACCTTTTCCA AGTGATCCTGGAGAAGCCCATCCGGATCCCCCGGTTCCTGTCCGTCAAAGCCTCCCATGT TTTAAAAGGATTTTTAAATAAGGACCCCAAAGAGAGGCTCGGCTGCCGGCCACAGACTGG ATTTTCTGACATCAAGTCCCACGCGTTCTTCCGCAGCATAGACTGGGACTTGATGCACAG ACAACTCAGATGCACAGACGCCCGGACGACGTGGACACCCAGACGATGTGGACGCACAGA CGACATGGACGCACAGACGATGTGGATGCACGGACGACGTAGACACACGGATGACTCATC CACAGATGACTCAGATGCACGGACACCCAGACGACGCGGACGCACAGACGACGCGGACGC ACAGATGACGTGGACGCACAGATGACGTGGACGCACGGACGACGTGGATGCATGGACGAC GTGGACGCACAGATGACCTGGACGCACGGACGACGTGGACGCACGGATGACTCAGATCCC CAGACGACTCAGATGCACGGACACCCAGATGACATGGATGCACGGACGACTCAGATCCAC AGATGACTCAAACGCACAGATGACTGGGATGCTCAGATGACCGCTGCTGTGCTGCCACCC CAGGGCTCTCTGGGCGTTTCCTGTGGTTTGGGCACCAGGAGCCTGGGAGTCCCATGCTGC CCCCAGGGCACTACCTCCTGGGCCCAGCCCTGCATCCGGTGGCAGGGCTCACCGTCATCA CCCCAACAGTGCAGGGTGGTCTCAGGGACCTCCTCTCATCATTGCCAAGAACTGGCTCCA GGATGTTTCCATGTGGCCGGCTAGTATGGCCAAAGTGGACCCTGGCGTGCTGTCCCCTTG GACGCCTCCAGGCCCTGCCCAGCACGTGGGGCTCGTCCATTCTGTGCCTGACCATGCTCT GCCATGCGGGGCCTAGCCCAGCCCCCCAGCCCTGCTGCTTCTCCCCACCCCACCCCCGCC ACCTCCACCAAGCCACCAGCATCCTGCCTGGCCCTACGGACAGCAGGGTCGTCCTGTGTC CAAAAGCCTCCTCCCCCTCAGCCCCTTCACTCGGGTCTCATGGGGCCCCTCTGTGGCCCC CAGCGCACAAGGCACACACCCACTATGGGGCCTTTGCACAGCTGTGCCCTCCCCAGGCTC CAGCCCTCACCTCCCCCAGGCTATTTCTCAGATGTCCCTTCAGAACTAGAGCCCTTGGGC CCCCAGCCCCATTGACACGGAACGGGCCCCCTGTTGTATCTCAGGTCACTGCTGTGGTTG CAGCCACAGGGGCAACACCTGTTACTGCCACAGCGTCCGACCTGGGGCCAGCGTGCATTC AAACGCACTGCTCTGAGAGGCCAGGACGTCCATGGGTTGGGCGCAGGGGGCGGCGGTGGG AAAAGGTGTCAGGCACCATGGGTCCCGACCTGGAGCCCACGTGCCAGCTGCAGAGATGGG CACTGAAGGCTTTTGAGCAAGAGGAGGAGGTAACGCTGGCCCCTGGGGATGCTGTCAGGG AAACTGAGGCAATCTTGAGCCCTCGGAGCAGAGAACGGGCTGGGCCAGGGGCTGGAGGAC CCTGG |
Protein Sequence | >5590 : length: 595 MPSRTGPKMEGSGGRVRLKAHYGGDIFITSVDAATTFEELCEEVRDMCRLHQQHPLTLKW VDSEGDPCTVSSQMELEEAFRLARQCRDEGLIIHVFPSTPEQPGLPCPGEDKSIYRRGAR RWRKLYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTC RKHMDSVMPSQEPPVDDKNEDADLPSEETDGIAYISSSRKHDSIKDDSEDLKPVIDGMDG IKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTE KHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEI CIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAP EILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRF LSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLMHRQLRCTDARTTWT PRRCGRTDDMDAQTMWMHGRRRHTDDSSTDDSDARTPRRRGRTDDADAQMTWTHR |