lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

94031

PubMed (Gene Name)

Literature evidence

20068077 (HTRA3)

cigarette smoke-induced methylation of HtrA3 could contribute to the etiology of chemoresistant disease in smoking-related lung cancer.

20154083 (HTRA3)

HtrA3 may be a previously uncharacterized mitochondrial cell death effector whose serine protease function may be crucial to modulating etoposide- and cisplatin-induced cytotoxicity in lung cancer cell lines.

30940659 (HTRA3)

Low HTRA3 expression is associated with Metastasis in Non-Small Cell lung cancer.

31260151 (HTRA3)

HtrA3 isoforms stimulate drug-induced apoptotic death of lung cancer cells via XIAP cleavage.