lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

912

PubMed (Gene Name)

Literature evidence

21258883 (CD1D)

CD1d gene polymorphisms are associated with breast, colorectal and lung cancers.

30864713 (CD1D)

In samples from lung cancer patients, the antitumor activities of all the T cells were enhanced with the increase of CD1D+DCs. Analysis of The cancer Genome Atlas data revealed that high levels of CD1D indicated better outcomes for patients. Collectively, CD1D enhanced DCbased antitumor immunity, not only by targeting NKT, but also by activating CD4+T and CD8+T cells.