lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	912
Symbol	CD1D
Synonymous	CD1A\|R3
Full name	CD1d molecule
Gene description	CD1D antigen, d polypeptide\|HMC class I antigen-like glycoprotein CD1D\|R3G1\|T-cell surface glycoprotein CD1d\|antigen-presenting glycoprotein CD1d\|differentiation antigen CD1-alpha-3\|thymocyte antigen CD1D
Cytoband	1q23.1
Gene type	protein-coding
Synonymous	MIM:188410; HGNC:HGNC:1637; Ensembl:ENSG00000158473; HPRD:01780; Vega:OTTHUMG00000022436

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.63C>G; p.V21V; 1:158181456-158181456	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.999C>T; p.G333G; 1:158184141-158184141	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.74delT; p.F26fs*43; 1:158181467-158181467	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.805G>A; p.V269M; 1:158183075-158183075	breast	carcinoma	Substitution - Missense
c.27C>T; p.L9L; 1:158181128-158181128	breast	carcinoma	Substitution - coding silent
c.364G>T; p.V122L; 1:158182067-158182067	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.571C>A; p.L191I; 1:158182274-158182274	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.423C>T; p.I141I; 1:158182126-158182126	skin	malignant_melanoma	Substitution - coding silent
c.996G>C; p.Q332H; 1:158184138-158184138	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.933G>A; p.A311A; 1:158183982-158183982	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.753G>A; p.G251G; 1:158183023-158183023	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.295G>A; p.V99M; 1:158181688-158181688	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.332C>T; p.P111L; 1:158182035-158182035	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.986+1G>A; p.?; 1:158184036-158184036	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Unknown
c.332C>T; p.P111L; 1:158182035-158182035	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.332C>T; p.P111L; 1:158182035-158182035	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.332C>T; p.P111L; 1:158182035-158182035	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.336G>A; p.L112L; 1:158182039-158182039	skin	malignant_melanoma	Substitution - coding silent
c.295G>A; p.V99M; 1:158181688-158181688	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.986+1G>A; p.?; 1:158184036-158184036	prostate	carcinoma	Unknown
c.951C>A; p.L317L; 1:158184000-158184000	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.566G>A; p.S189N; 1:158182269-158182269	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.154G>A; p.E52K; 1:158181547-158181547	skin	malignant_melanoma	Substitution - Missense
c.63C>T; p.V21V; 1:158181456-158181456	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.689A>G; p.Y230C; 1:158182959-158182959	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.88T>G; p.C30G; 1:158181481-158181481	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.411A>T; p.Q137H; 1:158182114-158182114	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.481T>G; p.L161V; 1:158182184-158182184	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.787C>T; p.L263F; 1:158183057-158183057	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.481T>G; p.L161V; 1:158182184-158182184	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.155A>G; p.E52G; 1:158181548-158181548	urinary_tract; bladder	carcinoma	Substitution - Missense
c.704G>A; p.W235*; 1:158182974-158182974	skin	malignant_melanoma	Substitution - Nonsense
c.265C>A; p.R89R; 1:158181658-158181658	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.326C>G; p.S109C; 1:158181719-158181719	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.185C>T; p.S62L; 1:158181578-158181578	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.495G>T; p.V165V; 1:158182198-158182198	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.621C>T; p.A207A; 1:158182891-158182891	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.764C>A; p.P255H; 1:158183034-158183034	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.409C>T; p.Q137*; 1:158182112-158182112	skin	malignant_melanoma	Substitution - Nonsense
c.619G>A; p.A207T; 1:158182889-158182889	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.793G>A; p.A265T; 1:158183063-158183063	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.775G>A; p.E259K; 1:158183045-158183045	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.470T>C; p.L157P; 1:158182173-158182173	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.265C>T; p.R89W; 1:158181658-158181658	breast	carcinoma	Substitution - Missense
c.327C>T; p.S109S; 1:158181720-158181720	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.989C>T; p.S330F; 1:158184131-158184131	skin	malignant_melanoma	Substitution - Missense
c.834C>T; p.S278S; 1:158183104-158183104	skin	malignant_melanoma	Substitution - coding silent
c.681A>T; p.S227S; 1:158182951-158182951	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.740G>A; p.G247D; 1:158183010-158183010	skin	malignant_melanoma	Substitution - Missense
c.144G>A; p.A48A; 1:158181537-158181537	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.252G>A; p.L84L; 1:158181645-158181645	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.252G>A; p.L84L; 1:158181645-158181645	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.268G>A; p.V90I; 1:158181661-158181661	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.379G>A; p.A127T; 1:158182082-158182082	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.252G>A; p.L84L; 1:158181645-158181645	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.142G>T; p.A48S; 1:158181535-158181535	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.347T>C; p.V116A; 1:158182050-158182050	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.142G>T; p.A48S; 1:158181535-158181535	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.306C>T; p.F102F; 1:158181699-158181699	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.164C>T; p.T55M; 1:158181557-158181557	prostate	carcinoma	Substitution - Missense
c.107T>A; p.F36Y; 1:158181500-158181500	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.986C>T; p.T329I; 1:158184035-158184035	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.165G>A; p.T55T; 1:158181558-158181558	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.412G>T; p.G138*; 1:158182115-158182115	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.635G>T; p.G212V; 1:158182905-158182905	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.393C>T; p.F131F; 1:158182096-158182096	skin	malignant_melanoma	Substitution - coding silent
c.777G>T; p.E259D; 1:158183047-158183047	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.653G>A; p.G218D; 1:158182923-158182923	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.655C>T; p.R219C; 1:158182925-158182925	salivary_gland	carcinoma; adenoid_cystic_carcinoma	Substitution - Missense
c.815G>T; p.G272V; 1:158183085-158183085	urinary_tract; bladder	carcinoma	Substitution - Missense
c.618G>T; p.K206N; 1:158182888-158182888	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.454A>G; p.T152A; 1:158182157-158182157	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.111C>T; p.A37A; 1:158181504-158181504	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.186G>A; p.S62S; 1:158181579-158181579	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.512G>A; p.W171*; 1:158182215-158182215	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.748C>G; p.P250A; 1:158183018-158183018	liver	carcinoma	Substitution - Missense
c.990C>T; p.S330S; 1:158184132-158184132	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.87C>T; p.R29R; 1:158181480-158181480	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.772G>A; p.D258N; 1:158183042-158183042	skin	malignant_melanoma	Substitution - Missense
c.197G>A; p.R66H; 1:158181590-158181590	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.197G>A; p.R66H; 1:158181590-158181590	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.574C>T; p.L192F; 1:158182277-158182277	skin	malignant_melanoma	Substitution - Missense
c.448G>A; p.E150K; 1:158182151-158182151	liver	carcinoma	Substitution - Missense
c.448G>A; p.E150K; 1:158182151-158182151	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.448G>A; p.E150K; 1:158182151-158182151	liver	carcinoma	Substitution - Missense
c.254A>G; p.Q85R; 1:158181647-158181647	liver	carcinoma	Substitution - Missense
c.549C>T; p.T183T; 1:158182252-158182252	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.294C>T; p.D98D; 1:158181687-158181687	pancreas	carcinoma	Substitution - coding silent
c.80C>T; p.P27L; 1:158181473-158181473	skin	malignant_melanoma	Substitution - Missense
c.418G>A; p.D140N; 1:158182121-158182121	skin	malignant_melanoma	Substitution - Missense
c.127C>T; p.R43C; 1:158181520-158181520	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.450G>T; p.E150D; 1:158182153-158182153	liver	carcinoma	Substitution - Missense
c.450G>T; p.E150D; 1:158182153-158182153	liver	carcinoma	Substitution - Missense
c.450G>T; p.E150D; 1:158182153-158182153	liver	carcinoma	Substitution - Missense
c.515C>T; p.T172M; 1:158182218-158182218	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.608-1G>A; p.?; 1:158182877-158182877	autonomic_ganglia	neuroblastoma	Unknown
c.831G>T; p.L277L; 1:158183101-158183101	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.787C>A; p.L263I; 1:158183057-158183057	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.791G>T; p.R264L; 1:158183061-158183061	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.665T>G; p.L222R; 1:158182935-158182935	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.548C>T; p.T183I; 1:158182251-158182251	skin	malignant_melanoma	Substitution - Missense
c.126G>A; p.T42T; 1:158181519-158181519	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1000G>A; p.V334I; 1:158184142-158184142	liver	carcinoma	Substitution - Missense
c.1000G>A; p.V334I; 1:158184142-158184142	liver	carcinoma	Substitution - Missense
c.225G>A; p.T75T; 1:158181618-158181618	liver	carcinoma	Substitution - coding silent
c.225G>A; p.T75T; 1:158181618-158181618	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.248C>T; p.T83M; 1:158181641-158181641	pancreas	carcinoma	Substitution - Missense
c.515C>A; p.T172K; 1:158182218-158182218	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.125C>A; p.T42K; 1:158181518-158181518	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.77T>C; p.F26S; 1:158181470-158181470	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Substitution - Missense
c.579G>T; p.E193D; 1:158182282-158182282	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.954T>C; p.I318I; 1:158184003-158184003	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.266G>A; p.R89Q; 1:158181659-158181659	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.774C>T; p.D258D; 1:158183044-158183044	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.948C>T; p.L316L; 1:158183997-158183997	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.774C>T; p.D258D; 1:158183044-158183044	prostate	carcinoma	Substitution - coding silent
c.693A>T; p.P231P; 1:158182963-158182963	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.784T>C; p.Y262H; 1:158183054-158183054	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.675T>C; p.H225H; 1:158182945-158182945	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.393C>G; p.F131L; 1:158182096-158182096	urinary_tract; bladder	carcinoma	Substitution - Missense
c.585G>A; p.G195G; 1:158182288-158182288	skin	malignant_melanoma	Substitution - coding silent
c.481T>C; p.L161L; 1:158182184-158182184	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.328+2T>C; p.?; 1:158181723-158181723	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.275G>A; p.R92Q; 1:158181668-158181668	breast	carcinoma	Substitution - Missense
c.790C>T; p.R264*; 1:158183060-158183060	breast	carcinoma	Substitution - Nonsense
c.4G>A; p.G2R; 1:158181105-158181105	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.843G>A; p.V281V; 1:158183113-158183113	skin	malignant_melanoma	Substitution - coding silent
c.134A>G; p.D45G; 1:158181527-158181527	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.378C>T; p.N126N; 1:158182081-158182081	skin	malignant_melanoma	Substitution - coding silent
c.732G>A; p.E244E; 1:158183002-158183002	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.636C>T; p.G212G; 1:158182906-158182906	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.700G>T; p.V234L; 1:158182970-158182970	lung	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation