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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

9046

PubMed (Gene Name)

Literature evidence

20139980 (DOK2)

Identification of DOK genes as lung tumor suppressors.

24255704 (DOK2)

DOK2 as a tumor suppressor in EGFR-mutant lung adenocarcinoma

30475228 (Dok2)

compound-heterozygous deletion of Dok2 and Dusp4 in mice resulted in lung tumorigenesis with short latency and high incidence, and that their co-deletion synergistically activated MAPK signaling and promoted cell proliferation.