lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

8991

PubMed (Gene Name)

Literature evidence

23977169 (SELENBP1)

Decreased SELENBP1 expression is an early event in lung squamous cell cancer tumorigenesis.

26956891 (SELENBP1)

Downregulation of selenium-binding protein 1 is associated with lung squamous cell carcinoma.

30002193 (SELENBP1)

Data demonstrate that Selenbp1 is a direct target of Nkx2-1, which inhibits lung adenocarcinoma growth in vivo. Selenbp1 is an important suppressor of lung tumor growth that functions in a positive feedback loop with Nkx2-1, and whose loss is associated with worse patient outcome.