lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	8991
Symbol	SELENBP1
Synonymous	HEL-S-134P\|LPSB\|SBP56\|SP56\|hSBP
Full name	selenium binding protein 1
Gene description	56 kDa selenium-binding protein\|epididymis secretory sperm binding protein Li 134P\|selenium-binding protein 1
Cytoband	1q21.3
Gene type	protein-coding
Synonymous	MIM:604188; HGNC:HGNC:10719; Ensembl:ENSG00000143416; HPRD:05007; Vega:OTTHUMG00000012498

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1058G>A; p.G353D; 1:151365268-151365268	oesophagus; upper_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1146G>A; p.R382R; 1:151365036-151365036	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.555G>A; p.P185P; 1:151366831-151366831	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.192C>T; p.P64P; 1:151369172-151369172	skin	malignant_melanoma	Substitution - coding silent
c.1317C>G; p.N439K; 1:151364645-151364645	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.584G>A; p.R195Q; 1:151366802-151366802	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.584G>A; p.R195Q; 1:151366802-151366802	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.584G>A; p.R195Q; 1:151366802-151366802	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1362C>T; p.A454A; 1:151364600-151364600	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.340C>T; p.R114W; 1:151369024-151369024	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1357C>T; p.P453S; 1:151364605-151364605	skin	malignant_melanoma	Substitution - Missense
c.6T>G; p.A2A; 1:151369768-151369768	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.715G>T; p.V239L; 1:151366403-151366403	breast	carcinoma	Substitution - Missense
c.1341G>A; p.G447G; 1:151364621-151364621	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.381C>T; p.I127I; 1:151368299-151368299	skin	malignant_melanoma	Substitution - coding silent
c.748C>T; p.P250S; 1:151366370-151366370	skin	malignant_melanoma	Substitution - Missense
c.748C>T; p.P250S; 1:151366370-151366370	skin	malignant_melanoma	Substitution - Missense
c.1255A>G; p.R419G; 1:151364927-151364927	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.879G>A; p.V293V; 1:151365811-151365811	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.131T>A; p.L44Q; 1:151369485-151369485	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1387G>A; p.G463R; 1:151364575-151364575	NS	malignant_melanoma	Substitution - Missense
c.1387G>A; p.G463R; 1:151364575-151364575	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.1387G>A; p.G463R; 1:151364575-151364575	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.882C>T; p.P294P; 1:151365808-151365808	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1374G>A; p.E458E; 1:151364588-151364588	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.410A>C; p.H137P; 1:151368270-151368270	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1145G>A; p.R382Q; 1:151365037-151365037	skin	malignant_melanoma	Substitution - Missense
c.1249C>G; p.L417V; 1:151364933-151364933	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.696C>T; p.D232D; 1:151366422-151366422	central_nervous_system; brain	glioma	Substitution - coding silent
c.1144C>T; p.R382W; 1:151365038-151365038	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.297C>A; p.L99L; 1:151369067-151369067	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.184C>T; p.R62W; 1:151369180-151369180	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1173G>C; p.Q391H; 1:151365009-151365009	urinary_tract; bladder	carcinoma	Substitution - Missense
c.453C>T; p.S151S; 1:151368227-151368227	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.704G>A; p.R235H; 1:151366414-151366414	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1165A>G; p.M389V; 1:151365017-151365017	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.157T>C; p.S53P; 1:151369459-151369459	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.870G>A; p.V290V; 1:151365820-151365820	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1032C>T; p.R344R; 1:151365575-151365575	skin	malignant_melanoma	Substitution - coding silent
c.1099G>A; p.E367K; 1:151365227-151365227	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1110G>C; p.K370N; 1:151365216-151365216	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.710A>G; p.E237G; 1:151366408-151366408	skin	malignant_melanoma	Substitution - Missense
c.642C>T; p.F214F; 1:151366744-151366744	skin	malignant_melanoma	Substitution - coding silent
c.642C>T; p.F214F; 1:151366744-151366744	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.552A>G; p.A184A; 1:151366834-151366834	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.933C>T; p.T311T; 1:151365674-151365674	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.761G>A; p.R254H; 1:151366357-151366357	liver	carcinoma	Substitution - Missense
c.779A>T; p.D260V; 1:151366339-151366339	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.761G>A; p.R254H; 1:151366357-151366357	liver	carcinoma	Substitution - Missense
c.1031G>A; p.R344H; 1:151365576-151365576	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.899G>A; p.G300D; 1:151365791-151365791	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.827G>T; p.R276L; 1:151366291-151366291	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.954C>T; p.D318D; 1:151365653-151365653	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1258G>A; p.E420K; 1:151364704-151364704	skin	malignant_melanoma	Substitution - Missense
c.110G>A; p.G37D; 1:151369506-151369506	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.910C>G; p.P304A; 1:151365780-151365780	central_nervous_system; brain	glioma	Substitution - Missense
c.1408A>C; p.I470L; 1:151364554-151364554	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1232A>C; p.K411T; 1:151364950-151364950	kidney	other; neoplasm	Substitution - Missense
c.252C>T; p.F84F; 1:151369112-151369112	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.9G>A; p.T3T; 1:151369765-151369765	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.412A>C; p.T138P; 1:151368268-151368268	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.412A>C; p.T138P; 1:151368268-151368268	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.884C>T; p.P295L; 1:151365806-151365806	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.688G>A; p.V230I; 1:151366430-151366430	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1193G>A; p.R398H; 1:151364989-151364989	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1193G>A; p.R398H; 1:151364989-151364989	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.913G>A; p.E305K; 1:151365777-151365777	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1193G>A; p.R398H; 1:151364989-151364989	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1193G>A; p.R398H; 1:151364989-151364989	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.433G>T; p.G145W; 1:151368247-151368247	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1061G>T; p.S354I; 1:151365265-151365265	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.588C>T; p.H196H; 1:151366798-151366798	stomach	adenocarcinoma	Substitution - coding silent
c.1332G>A; p.V444V; 1:151364630-151364630	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.990G>T; p.G330G; 1:151365617-151365617	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.486T>G; p.G162G; 1:151366900-151366900	pancreas	carcinoma	Substitution - coding silent
c.302C>T; p.S101F; 1:151369062-151369062	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1303G>T; p.G435W; 1:151364659-151364659	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.805G>A; p.A269T; 1:151366313-151366313	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.805G>A; p.A269T; 1:151366313-151366313	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1265C>T; p.S422F; 1:151364697-151364697	skin	malignant_melanoma	Substitution - Missense
c.1317_1318insGTTGAAC; p.P440fs*21; 1:151364644-151364645	lung	carcinoma; adenocarcinoma	Insertion - Frameshift
c.341G>T; p.R114L; 1:151369023-151369023	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.482G>C; p.G161A; 1:151366904-151366904	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.30C>G; p.P10P; 1:151369744-151369744	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1093G>T; p.E365*; 1:151365233-151365233	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1407C>A; p.D469E; 1:151364555-151364555	urinary_tract; bladder	carcinoma	Substitution - Missense
c.760C>T; p.R254C; 1:151366358-151366358	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.614C>A; p.A205E; 1:151366772-151366772	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.220C>G; p.H74D; 1:151369144-151369144	urinary_tract; bladder	carcinoma	Substitution - Missense
c.742C>T; p.L248F; 1:151366376-151366376	skin	malignant_melanoma	Substitution - Missense
c.827G>A; p.R276H; 1:151366291-151366291	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5-4A>T; p.?; 1:151369773-151369773	thyroid	other; neoplasm	Unknown
c.338C>T; p.P113L; 1:151369026-151369026	skin	malignant_melanoma	Substitution - Missense
c.1338C>T; p.F446F; 1:151364624-151364624	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation