Links to all GeneRIF Items | 8797 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 19203830 (TNFRSF10A) | Coding polymorphisms in Casp5, Casp8 and DR4 genes may play a role in predisposition to lung cancer. |
| 23661154 (TNFRSF10A) | Investigated the association between G422A, C626G, A683C and A1322G polymorphisms in DR4 gene and lung cancer. |
| 26238205 (TNFRSF10A) | Results showed DR4 promotor methylation and low protein expression level in patients with lung squamous carcinoma which correlated with the prognosis of the disease. |
| 27750195 (TNFRSF10A) | The nanovectorization of TRAIL enhanced its binding to both DR4 and DR5 receptors at 37 degrees C and could potentially sensitized cancer cells to TRAIL induced apoptosis through simultaneous activation of DR4 and DR5 as described in this paper for the non-small lung carcinoma cell line (H1703), the two hepatocarcinoma cell lines (SK-Hep1, HUH) and the colon carcinoma cell line (HCT116WT). |
| 28039489 (TNFRSF10A) | Apoptosis induced by TRAIL is preferentially induced by TRAIL-R1 pathway in breast/lung tumor cells. |