Links to all GeneRIF Items | 8795 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 17548900 (TNFRSF10B) | Quercetin increases expression of death receptor (DR) 5, but has no effect on that of other components of the death-inducing signaling complex in lung in non-small cell lung cancer cells. |
| 19243385 (TNFRSF10B) | inhibition of c-FLIP(L) expression might be a potential strategy for lung cancer therapy, especially for those lung cancers resistant to the agonistic antibody against death receptors |
| 19661294 (TNFRSF10B) | Low DR5 is associated with non-small cell lung cancer. |
| 20422457 (TNFRSF10B) | Single-nucleotide polymorphisms in TNFRSF10B gene is associated with early-stage non-small-cell lung cancer. |
| 20450916 (TNFRSF10B) | Inhibition of tissue transglutaminase 2 sensitizes TRAIL-resistant lung cancer cells through upregulation of death receptor 5. |
| 23608376 (TNFRSF10B) | Assessed if casticin induces caspase-mediated apoptosis via activation of mitochondrial pathway and upregulation of DR5 in human lung cancer cells. |
| 23839018 (TNFRSF10B) | TNFRSF10B polymorphisms and haplotypes are associated with increased risk of non-small cell lung cancer. |
| 25917567 (TNFRSF10B) | Taken together, our results strongly suggest that FLLL12 induces apoptosis of lung cancer cell lines by posttranscriptional regulation of DR5 through activation of protein tyrosine phosphatase(s). |
| 27129166 (TNFRSF10B) | The oncogene-like extracellular miR-1246 could act as a signaling messenger between irradiated and non-irradiated lung cancer cells, more importantly, it contributes to cell radioresistance by directly suppressing the DR5 gene. |
| 27750195 (TNFRSF10B) | The nanovectorization of TRAIL enhanced its binding to both DR4 and DR5 receptors at 37 degrees C and could potentially sensitized cancer cells to TRAIL induced apoptosis through simultaneous activation of DR4 and DR5 as described in this paper for the non-small lung carcinoma cell line (H1703), the two hepatocarcinoma cell lines (SK-Hep1, HUH) and the colon carcinoma cell line (HCT116WT). |
| 30911274 (TNFRSF10B) | Serum soluble DR5 levels association with survival in the small-cell lung cancer patients.Upregulation of serum soluble DR5 level in the small-cell lung cancer patients in comparison with healthy controls. |
| 31638235 (TNFRSF10B) | High DR5 expression is associated with lung adenocarcinoma. |
| 32777260 (TNFRSF10B) | Luteolin enhances TRAIL sensitivity in non-small cell lung cancer cells through increasing DR5 expression and Drp1-mediated mitochondrial fission. |