Links to all GeneRIF Items | 8678 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 18184459 (BECN1) | The positive rates of Beclin1 and MAPLC3 were significantly lower in non-small cell lung cancer tissues than in adjacent non-cancerous tissues and normal tissues. |
| 21556768 (BECN1) | Both mRNA and protein levels of Beclin-1 and LC3-II were significantly decreased in lung cancer tissues which suggested that autophagy may be involved in the pathogenesis of lung cancer. |
| 21777947 (BECN1) | A progressively reduced Beclin-1 expression is correlated with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. |
| 23216071 (BECN1) | The accelerated autophagic status in non-small cell lung carcinoma is unrelated to Beclin 1 and BNIP3 expression, but does show significant association with Bcl-2 reactivity. |
| 24755562 (BECN1) | Our results indicated that paclitaxel resistance of lung cancer is associated with downregulation of miR-17-5p expression which might cause upregulation of BECN1 expression. |
| 24760274 (BECN1) | our results suggest that the activated Stat3 may represent an important mechanism for Beclin 1 downregulation in nonsmall cell lung cancer development |
| 25175672 (BECN1) | Study demonstrated that expression of LKB1 and Beclin1 was reduced in non-small cell lung cancer (NSCLC) tissues, and the reduced expression of these proteins, is an independent indicator for the overall survival of NSCLC patients. |
| 26617774 (BECN1) | Suggest that Beclin 1 and p62 could serve as potential indicators for the prognosis of patients with non-small cell lung cancer. |
| 27175789 (BECN1) | the overexpression of Beclin 1 promoted apoptosis and decreased invasion by upregulating the expression of ECRG4 in A549 lung adenocarcinoma cells. Therefore, the selection of Beclin l as a target for gene therapy represents a more effective method for the treatment of lung cancer. |
| 28558758 (BECN1) | High levels of Beclin1 is associated with non-small cell lung cancer. |
| 29545906 (BECN1) | The results suggest that autophagy-associated proteins LC3A, LC3B, and Beclin-1 might be potential biomarkers for subclassification, differentiation, and local metastasis in primary lung tumor. |
| 30184615 (BECN1) | high expression predicts longer survival in locally advanced non-small cell lung cancer |
| 30362635 (BECN1) | Low beclin 1 expression is associated with lung cancer. |
| 31272261 (BECN1) | The studies here revealed an oncosupportive role of BECN1 in the migration of non-small cell lung cancer cells through regulating the ubiquitination of Vimentin. |
| 22843615 (Becn1) | Aerosol delivery of beclin1 enhanced the anti-tumor effect of radiation in the lungs of K-rasLA1 mice |