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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

8434

PubMed (Gene Name)

Literature evidence

12810630 (RECK)

Histone deacetylase inhibition increases RECK expression which inhibits MMP activation and cancer cell invasion. Trichostatin A up-regulated RECK via transcriptional activation in CL-1 human lung cancer cells. This attenuated MMP-2 activity.

17233834 (RECK)

downregulation of the metastasis suppressor RECK is caused by promoter methylation in non-small cell lung cancer

17714826 (RECK)

suppression of RECK expression is involved in the progression of adenocarcinoma of the lung

18194466 (RECK)

The K23 motifs of RECK protein can inhibit MMP-9 secretion and activity and attenuate metastasis of lung cancer cells.

24162673 (RECK)

MiR-92b may promote nonsmall cell lung cancer cell growth and motility partially by inhibiting RECK.

24510537 (RECK)

no association between the RECK polymorphism and chemotherapy response status in non-small-cell lung cancer in Chinese cohort

26026961 (RECK)

A decrease in SPRY2 and RECK expression by nickel-induced miR-21 may promote invasiveness in lung cancer cells.

32138716 (RECK)

LncRNA MAGI2-AS3 is downregulated in non-small cell lung cancer and may be a sponge of miR-25.