lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

7150

PubMed (Gene Name)

Literature evidence

11844605 (TOP1)

Point mutations in the topoisomerase I gene in patients with non-small cell lung cancer treated with irinotecan

24327519 (TOP1)

Collectively, these findings suggest that the combinatorial inhibition of MET and Top1 is a potentially efficacious treatment strategy for Small cell lung cancer .

25987486 (TOP1)

both TOP1 and TDP1 were upregulated in the tumor tissue compared to the adjacent non-tumor tissue in non-small cell lung cancer tissue