lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

7066

PubMed (Gene Name)

Literature evidence

14689068 (THPO)

Increased serum TPO levels in patients with thrombocytosis in lung cancer which may be related to the activity of neoplasms.

32337844 (THPO)

Endogenous thrombopoietin promotes non-small-cell lung carcinoma cell proliferation and migration by regulating EGFR signalling.

31301081 (Thpo)

Study of hepatocarcinogenesis induced by diethylnitrosamine in B6C3F1 mice, the BrafV637E mutation, corresponding to the human BRAFV600E mutation, suggested that the TPO-mediated macroenvironmental changes involving the liver and bone marrow may promote proliferation of the BRAFV600E-mutated hepatocytes, but cause hematological, renal, and pulmonary disorders that lead to death.