Links to all GeneRIF Items | 6510 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 23213057 (SLC1A5) | SLC1A5 plays a key role in Gln transport controlling lung cancer cells' metabolism, growth, and survival. |
| 29151270 (SLC1A5) | Results provide evidence that ASCT2 enhances glutamine uptake in glycolipid-enriched microdomain/rafts in GD2(+) small-cell lung cancer cells, leading to the enhancement of cell proliferation and migration. |
| 29326164 (SLC1A5) | Data suggest that amino acid uptake via ASCT2/SLC1A5 is required for cell proliferation/tumor growth independently of LAT1/SLC7A5; in part, these studies were conducted in lung and colon adenocarcinoma cell lines and involved gene knockout techniques. (ASCT2/SLC1A5 = solute carrier family-1 member-5; LAT1/SLC7A5 = solute carrier family-7 member-5) |
| 29455869 (SLC1A5) | Our results indicate that overexpression of SLC1a5 is associated with shorter overall survival in non-small cell lung cancer |