Cancer metastasis database

Annotation category 5

Gene information

Gene ID 6510
Symbol

SLC1A5

Synonymous

AAAT|ASCT2|ATBO|M7V1|M7VS1|R16|RDRC

Full name

solute carrier family 1 (neutral amino acid transporter), member 5

Gene description

ATB(0)|RD114 virus receptor|RD114/simian type D retrovirus receptor|baboon M7 virus receptor|neutral amino acid transporter B|neutral amino acid transporter B(0)|sodium-dependent neutral amino acid transporter type 2|solute carrier family 1 member 5

Cytoband

19q13.3

Gene type

protein-coding

Synonymous

MIM:109190; HGNC:HGNC:10943; Ensembl:ENSG00000105281; HPRD:00173; Vega:OTTHUMG00000183434

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1294C>T; p.P432S; 19:46777069-46777069

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1245C>T; p.I415I; 19:46777219-46777219

 skinmalignant_melanomaSubstitution - coding silent

c.1021G>C; p.V341L; 19:46778712-46778712

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.1066A>G; p.T356A; 19:46777398-46777398

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1368C>T; p.I456I; 19:46776995-46776995

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1401T>A; p.C467*; 19:46775735-46775735

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Nonsense

c.901C>T; p.R301C; 19:46778832-46778832

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.241T>C; p.L81L; 19:46787725-46787725

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1254-1G>A; p.?; 19:46777110-46777110

 skinmalignant_melanomaUnknown

c.1025C>T; p.T342M; 19:46778708-46778708

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.1025C>T; p.T342M; 19:46778708-46778708

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1130T>C; p.F377S; 19:46777334-46777334

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.1143C>T; p.I381I; 19:46777321-46777321

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.604C>T; p.R202C; 19:46784522-46784522

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.930G>A; p.L310L; 19:46778803-46778803

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.604C>T; p.R202C; 19:46784522-46784522

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.902G>A; p.R301H; 19:46778831-46778831

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.758A>G; p.E253G; 19:46782449-46782449

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.826T>C; p.Y276H; 19:46778907-46778907

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1463G>A; p.R488H; 19:46775673-46775673

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1463G>A; p.R488H; 19:46775673-46775673

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1478G>T; p.S493I; 19:46775658-46775658

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.1169C>T; p.A390V; 19:46777295-46777295

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.768C>T; p.I256I; 19:46782439-46782439

 skinmalignant_melanomaSubstitution - coding silent

c.737G>A; p.R246Q; 19:46782470-46782470

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1254-2A>T; p.?; 19:46777111-46777111

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.1106G>A; p.G369D; 19:46777358-46777358

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1560C>G; p.L520L; 19:46775576-46775576

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.673G>A; p.E225K; 19:46782534-46782534

 skinmalignant_melanomaSubstitution - Missense

c.768C>A; p.I256I; 19:46782439-46782439

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.673G>A; p.E225K; 19:46782534-46782534

 skinmalignant_melanomaSubstitution - Missense

c.528_529insC; p.S177fs*33; 19:46787437-46787438

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.506C>A; p.A169E; 19:46787460-46787460

 livercarcinomaSubstitution - Missense

c.1185C>T; p.C395C; 19:46777279-46777279

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1185C>T; p.C395C; 19:46777279-46777279

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1286C>T; p.A429V; 19:46777077-46777077

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1266A>T; p.T422T; 19:46777097-46777097

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1067C>T; p.T356M; 19:46777397-46777397

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.817A>G; p.I273V; 19:46782390-46782390

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.477C>T; p.S159S; 19:46787489-46787489

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1397C>T; p.S466F; 19:46775739-46775739

 skinmalignant_melanomaSubstitution - Missense

c.782C>T; p.S261F; 19:46782425-46782425

 skinmalignant_melanomaSubstitution - Missense

c.782C>T; p.S261F; 19:46782425-46782425

 skinmalignant_melanomaSubstitution - Missense

c.1144G>A; p.G382S; 19:46777320-46777320

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1604C>T; p.S535F; 19:46775532-46775532

 skinmalignant_melanomaSubstitution - Missense

c.1144G>A; p.G382S; 19:46777320-46777320

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1426G>A; p.A476T; 19:46775710-46775710

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.567-8C>T; p.?; 19:46784567-46784567

 pancreascarcinomaUnknown

c.625G>A; p.E209K; 19:46784129-46784129

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.996C>A; p.N332K; 19:46778737-46778737

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1293_1294CC>TT; p.P432S; 19:46777069-46777070

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1565A>G; p.K522R; 19:46775571-46775571

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; essential_thrombocythaemiaSubstitution - Missense

c.1306G>T; p.V436F; 19:46777057-46777057

 pancreascarcinomaSubstitution - Missense

c.1306G>T; p.V436F; 19:46777057-46777057

 pancreascarcinomaSubstitution - Missense

c.1369C>T; p.L457L; 19:46776994-46776994

 skinmalignant_melanomaSubstitution - coding silent

c.828C>T; p.Y276Y; 19:46778905-46778905

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.828C>T; p.Y276Y; 19:46778905-46778905

 thyroidother; neoplasmSubstitution - coding silent

c.379C>T; p.L127L; 19:46787587-46787587

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - coding silent

c.717C>T; p.I239I; 19:46782490-46782490

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.995A>T; p.N332I; 19:46778738-46778738

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.959T>C; p.V320A; 19:46778774-46778774

 skinmalignant_melanomaSubstitution - Missense

c.919C>A; p.L307M; 19:46778814-46778814

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.770G>A; p.R257H; 19:46782437-46782437

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.49C>G; p.P17A; 19:46787917-46787917

 thyroidother; neoplasmSubstitution - Missense

c.989G>A; p.R330H; 19:46778744-46778744

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.989G>A; p.R330H; 19:46778744-46778744

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1578G>A; p.G526G; 19:46775558-46775558

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.358G>A; p.D120N; 19:46787608-46787608

 livercarcinomaSubstitution - Missense

c.358G>A; p.D120N; 19:46787608-46787608

 livercarcinomaSubstitution - Missense

c.1496T>A; p.I499K; 19:46775640-46775640

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.999C>T; p.P333P; 19:46778734-46778734

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1473G>A; p.S491S; 19:46775663-46775663

 oesophaguscarcinomaSubstitution - coding silent

c.1002C>T; p.Y334Y; 19:46778731-46778731

 thyroidcarcinomaSubstitution - coding silent

c.1233C>T; p.F411F; 19:46777231-46777231

 skinmalignant_melanomaSubstitution - coding silent

c.1410C>T; p.L470L; 19:46775726-46775726

 skinmalignant_melanomaSubstitution - coding silent

c.1171G>A; p.A391T; 19:46777293-46777293

 stomachcarcinoma; adenocarcinomaSubstitution - Missense