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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

6470

PubMed (Gene Name)

Literature evidence

17420066 (SHMT1)

Subjects carrying the combined 3+ risk variant genotypes of SHMT1 had an increased risk of lung cancer.

25412303 (SHMT1)

SHMT1 knockdown in lung cancer cells leads to cell cycle arrest and to p53-dependent apoptosis.

26553359 (SHMT1)

we identified SHMT1 as a target gene of miR-198. In conclusion, miR-198 suppressed proliferation of lung adenocarcinoma cells both in vitro and in vivo by directly targeting SHMT1.

31124332 (SHMT1)

miR-218-5p suppresses the killing effect of natural killer cells to lung adenocarcinoma cells by targeting SHMT1.