lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

6009

PubMed (Gene Name)

Literature evidence

20554106 (RHEB)

Results suggest that Rheb is a critical target for farnesyltransferase inhibitor therapy in non-small cell lung cancer cells.

27034171 (RHEB)

Describe a novel interaction between Rheb and the tumor suppressor RASSF1A. This interaction may allow coordinate upregulation of Hippo while TOR is suppressed to modulate the balance of apoptosis and autophagy in lung tumor cells.