Cancer metastasis database

Annotation category 5

Gene information

Gene ID 6009
Symbol

RHEB

Synonymous

RHEB2

Full name

Ras homolog enriched in brain

Gene description

GTP-binding protein Rheb|Ras homolog enriched in brain 2

Cytoband

7q36

Gene type

protein-coding

Synonymous

MIM:601293; HGNC:HGNC:10011; Ensembl:ENSG00000106615; HPRD:03188; Vega:OTTHUMG00000157330

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.146T>A; p.V49E; 7:151484783-151484783

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.118G>A; p.E40K; 7:151490949-151490949

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.118G>A; p.E40K; 7:151490949-151490949

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.503A>G; p.E168G; 7:151467171-151467171

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.118G>A; p.E40K; 7:151490949-151490949

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.193-1_193GG>TC; p.?; 7:151477415-151477416

 lungcarcinoma; adenocarcinomaUnknown

c.411G>C; p.L137F; 7:151470622-151470622

 skinmalignant_melanomaSubstitution - Missense

c.411G>C; p.L137F; 7:151470622-151470622

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.68C>A; p.T23K; 7:151490999-151490999

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.70A>G; p.I24V; 7:151490997-151490997

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.223T>G; p.S75A; 7:151477385-151477385

 parathyroidcarcinomaSubstitution - Missense

c.103T>C; p.Y35H; 7:151490964-151490964

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.125C>A; p.T42N; 7:151484804-151484804

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.310T>C; p.L104L; 7:151471571-151471571

 skinmalignant_melanomaSubstitution - coding silent

c.236A>G; p.N79S; 7:151477372-151477372

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.178G>C; p.D60H; 7:151484751-151484751

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.173T>G; p.L58R; 7:151484756-151484756

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.415G>A; p.E139K; 7:151470618-151470618

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.417A>T; p.E139D; 7:151470616-151470616

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.68C>T; p.T23M; 7:151490999-151490999

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.68C>T; p.T23M; 7:151490999-151490999

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.416A>G; p.E139G; 7:151470617-151470617

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.214C>G; p.Q72E; 7:151477394-151477394

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.180C>T; p.D60D; 7:151484749-151484749

 stomachadenocarcinomaSubstitution - coding silent

c.333-7C>T; p.?; 7:151471448-151471448

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaUnknown

c.62C>T; p.S21L; 7:151491005-151491005

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.187G>T; p.G63W; 7:151484742-151484742

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.159A>T; p.E53D; 7:151484770-151484770

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.103T>A; p.Y35N; 7:151490964-151490964

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.103T>A; p.Y35N; 7:151490964-151490964

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.103T>A; p.Y35N; 7:151490964-151490964

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.103T>A; p.Y35N; 7:151490964-151490964

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.103T>A; p.Y35N; 7:151490964-151490964

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.415G>T; p.E139*; 7:151470618-151470618

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.415G>T; p.E139*; 7:151470618-151470618

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.193-9delT; p.?; 7:151477424-151477424

 stomachadenocarcinomaUnknown

c.85G>A; p.G29S; 7:151490982-151490982

 breastcarcinomaSubstitution - Missense

c.118G>C; p.E40Q; 7:151490949-151490949

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.513C>T; p.D171D; 7:151467161-151467161

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.104A>G; p.Y35C; 7:151490963-151490963

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.104A>G; p.Y35C; 7:151490963-151490963

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.332+6T>A; p.?; 7:151471543-151471543

 stomachadenocarcinomaUnknown

c.74A>G; p.Q25R; 7:151490993-151490993

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.196G>T; p.E66*; 7:151477412-151477412

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.348G>A; p.L116L; 7:151471426-151471426

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.529G>T; p.G177C; 7:151467145-151467145

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.517G>A; p.A173T; 7:151467157-151467157

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.125C>T; p.T42I; 7:151484804-151484804

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense