lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

5740

PubMed (Gene Name)

Literature evidence

17374734 (PTGIS)

PGIS promoter haplotype can play an important role in the predisposition for lung cancer and CpG methylation provides an epigenetic mechanism for the down-regulated PGIS expression.

19138979 (Ptgis)

PGIS/ IP transgenic animals with lung-specific PPARgamma overexpression also developed fewer lung tumors.