Links to all GeneRIF Items | 5734 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 17611676 (PTGER4) | Results show co-expression of cyclooxygenase-2 and prostaglandin E2 receptors EP1, 2 and 4 in non-small cell lung cancer cells concomitant with the synthesis of PGE2. |
| 20353998 (PTGER4) | Increased expression of PGE2 in the lung tumor microenvironment may initiate a mitogenic signaling cascade composed of EP4, betaArrestin1, and c-Src which mediates cancer cell migration. |
| 27544059 (PTGER4) | High PTGER4 methylation is associated with lung cancer. |
| 31167696 (PTGER4) | SHOX2 and PTGER4 methylation detection in blood plasma has certain value in the early diagnosis of lung cancer |
| 17018624 (Ptger4) | EP4 receptor signaling modulates tumor cell adhesion, migration, invasion, as well as colony formation in lung and colorectal cancer. |