lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

5617

PubMed (Gene Name)

Literature evidence

24512221 (PRL)

PRL is ectopically activated in a subset of very aggressive lung tumors, associated with a rapid fatal outcome, in a cohort of 293 lung tumor patients and in an external independent series of patients; analysis of the PRL transcripts in lung tumors and cell lines revealed systematic truncations of their 5' regions, including the signal peptide-encoding portions.