Protein phosphatase 2A was not associated with carcinoma progression of lung neoplasms.

EphB3 suppresses non-small-cell lung cancer metastasis via a PP2A/RACK1/Akt signalling complex

Results suggest that Tgase-2/PP2A/JNK might be a novel axis that affects N-cadherin switching in the epithelial-mesenchymal-transition (EMT) of A549 lung cancer cells.

Data show that protein phosphatase-2A (PP2A) was upregulated in lung adenocarcinoma cell lines that were transfected with midline 1 E3 ubiquitin-protein ligase (MID1)-siRNA, suggesting MID1 negatively regulates PP2A in lung adenocarcinoma.

PP2A overexpression is associated with lung metastasis in colorectal cancer .

Down-regulation of Protein phosphatase-2A leads to Down-regulation of Shp-2 tyrosine phosphatase in Lewis lung carcinoma tumor variants

We found that the cancer-associated A-alpha mutations increased the incidence of cancer by 50 to 60% in lungs of FVB mice treated with benzopyrene, demonstrating that PP2A acts as a tumor suppressor.