lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

54345

PubMed (Gene Name)

Literature evidence

22018271 (SOX18)

Heterogeneous methylation in the promoter region of SOX18 was associated with cancer progression in non-small cell lung cancer.

25310193 (SOX18)

SOX18 may be involved in the progression of Non small cell lung cancer.

29115529 (SOX18)

Results showed that on the contrary of the mRNA level, the protein levels of SOX18 were higher in lung adenocarcinoma (AC) cases compared to levels noted in the non-malignant lung tissues (NMLTs). The disparity between the mRNA and protein levels of the SOX18 transcription factor was caused by miR-7a and miR-24-3p, although the mechanism through which lung cancer cells downregulate miRNA molecule levels is still unclear.